Patents by Inventor Derek Saunders

Derek Saunders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-Phenyl-2-DimethylaminomethylCyclohexane Compounds and Therapies for Depressive Symptoms, Pain and Incontinence
    Publication number: 20110263699
    Abstract: Metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for producing a medicament used for treating depression, and related methods of treating depression, pain and urinary incontinence.
    Type: Application
    Filed: July 1, 2011
    Publication date: October 27, 2011
    Applicant: GRUENENTHAL GmbH
    Inventors: Elmar Friderichs, Wolfgang Strassburger, Ulrich Jahnel, Derek Saunders, Hagen-Heinrich Hennies, Werner Englberger, Helmut Buschmann, Joerg Holenz, Oswald Zimmer
  • Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions
    Publication number: 20110184020
    Abstract: Vanilloid receptor ligand compounds corresponding to formula I: a process for producing such compounds, pharmaceutical compositions containing them, and the use of such compounds to treat pain and various other vanilloid receptor mediated conditions.
    Type: Application
    Filed: March 31, 2011
    Publication date: July 28, 2011
    Applicant: Gruenenthal GmbH
    Inventors: Robert FRANK, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Michael Przewosny, Bernd Sundermann, Jeewoo Lee
  • Spirocyclic cyclohexane compounds
    Patent number: 7960404
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I in which R1 and R2 form a pyrrolidine ring or an azetidine ring and which exhibit increased metabolic stability, a process for producing such spirocyclic cyclohexane compounds, pharmaceutical compositions containing such spirocyclic cyclohexane compounds, and the use of such spirocyclic cyclohexane compounds to treat or inhibit pain and/or other disorders.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: June 14, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Schunk, Derek Saunders, Stephanie Harlfinger, Sonja Steufmehl
  • Spirocyclic Cyclohexane Compounds
    Publication number: 20100048554
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I In which R1, R2, R3 and R5 through R10 and X have defined meanings, a process for their preparation, pharmaceutical compositions containing such compounds, and the use of such spirocyclic cyclohexane compounds in the treatment and/or inhibition of pain and other conditions mediated by the ORL-1 or the ?-opioid receptor.
    Type: Application
    Filed: August 21, 2009
    Publication date: February 25, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Saskia Zemolka, Derek Saunders, Michael Gruss, Heinz Graubaum
  • Spirocyclic Cyclohexane Compounds
    Publication number: 20100048553
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I in which R1 and R2 form a pyrrolidine ring or an azetidine ring and which exhibit increased metabolic stability, a process for producing such spirocyclic cyclohexane compounds, pharmaceutical compositions containing such spirocyclic cyclohexane compounds, and the use of such spirocyclic cyclohexane compounds to treat or inhibit pain and/or other disorders.
    Type: Application
    Filed: August 21, 2009
    Publication date: February 25, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan SCHUNK, Derek SAUNDERS, Stephanie HARLFINGER, Sonja STEUFMEHL
  • VR1 Receptor Ligands and u-Opioid Receptor Ligands for the Treatment of Pain
    Publication number: 20090286831
    Abstract: A pharmaceutical composition comprising i) at least one composition that has affinity to the ?-opioid receptor, and at least one compound that has affinity to the VR1 receptor, or ii) at least one compound, in particular at least one compound corresponding to formula (I), (II), (III), (IV) or (V), that has affinity to the ?-opioid receptor and to the VR1 receptor, and also to the use of the pharmaceutical compositions i) and ii) for the production of a drug for the treatment of pain.
    Type: Application
    Filed: April 17, 2009
    Publication date: November 19, 2009
    Applicant: Gruenenthal GMBH
    Inventors: Babette-Yvonne KOEGEL, Thomas CHRISTOPH, Gregor BAHRENBERG, Robert FRANK, Wolfgang SCHROEDER, Jean DE VRY, Eric-Paul PAQUES, Derek SAUNDERS, Klaus SCHIENE, Bernd SUNDERMANN, Jeewoo LEE, Hyung-Chul RYU
  • Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process for Making Them, and Use Thereof for Treating Pain and Other Conditions
    Publication number: 20090156590
    Abstract: Vanilloid receptor ligand compounds corresponding to formula I: pharmaceutical compositions containing such compounds, a process for producing such compounds, and methods of using such compounds for treating or inhibiting pain and various other disorders or conditions.
    Type: Application
    Filed: April 15, 2008
    Publication date: June 18, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Robert FRANK, Gregor BAHRENBERG, Thomas CHRISTOPH, Klaus SCHIENE, Jean DE VRY, Derek SAUNDERS, Bernd SUNDERMANN, Jeewoo LEE
  • Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position
    Publication number: 20080293749
    Abstract: Pyrrolidine(thi)one compounds substituted by heterocyclic substituents in the 3-position, their preparation and use in pharmaceutical compositions, in particular as immunomodulators for treatment and/or inhibition of inflammatory and autoimmune diseases and haematological-oncological diseases.
    Type: Application
    Filed: June 2, 2008
    Publication date: November 27, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Sven FRORMANN, Stefanie FROSCH, Carsten GRIEBEL, Derek SAUNDERS, Fritz THEIL, Heinz GRAUBAUM
  • Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions
    Publication number: 20080275044
    Abstract: Compounds corresponding to formula I: which act as vanilloid receptor ligands, pharmaceutical compositions containing such compounds, a process for the producing such compounds, and the use thereof to treat or inhibit pain and/or various other disorders or conditions.
    Type: Application
    Filed: April 11, 2008
    Publication date: November 6, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Robert Frank, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Bernd Sundermann, Jeewoo Lee
  • Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions
    Publication number: 20080269289
    Abstract: Compounds corresponding to formula I: which act as vanilloid receptor ligands, pharmaceutical composition s containing such compounds, a method for producing the compounds, and the use of such compounds to treat pain and various other conditions.
    Type: Application
    Filed: April 11, 2008
    Publication date: October 30, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Robert Frank, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Jeewoo Lee
  • Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions
    Publication number: 20080262039
    Abstract: Vanilloid receptor ligand compounds corresponding to formula I: a process for producing such compounds, pharmaceutical compositions containing them, and the use of such compounds to treat pain and various other vanilloid receptor mediated conditions.
    Type: Application
    Filed: April 15, 2008
    Publication date: October 23, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Robert FRANK, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek Saunders, Michael Przewosny, Bernd Sundermann, Jewoo Lee
  • Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants
    Patent number: 7384961
    Abstract: Saturated and unsaturated heteroarylcycloalkylmethyl-amine compounds corresponding to formula I, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of saturated and unsaturated heteroarylcycloalkylmethyl-amines for the preparation of pharmaceutical formulations. pharmaceutical formulations and related methods of treatment or prophylaxis of certain condition, especially depression and/or pain, are also disclosed.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: June 10, 2008
    Assignee: Gruenenthal GmbH
    Inventors: Petra Bloms-Funke, Claudia Puetz, Ivars Graudums, Achim Kless, Carsten Griebel, Hagen-Heinrich Hennies, Dagmar Kaulartz, Sabine Reinardy, Derek Saunders, Klaus Schiene, Bernd Sundermann, Werner Englberger, Oswald Zimmer
  • Spirocyclic cyclohexane compounds
    Patent number: 7332519
    Abstract: Spirocyclic cyclohexane compounds, methods for their production, pharmaceutical compositions containing these compounds, and the use of these spirocyclic cyclohexane compounds for treating conditions associated with the nociceptin/ORL1 receptor system, e.g. pain, drug withdrawal, anxiety, etc.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: February 19, 2008
    Assignee: Gruenenthal GmbH
    Inventors: Claudia Hinze, Bernd Sundermann, Stefan Oberboersch, Werner Englberger, Elmark Friderichs, Sven Frormann, Babette-Yvonne Koegel, Klaus Linz, Beatrix Merla, Derek Saunders, Wolfgang Schroeder, Hans Schick, Birgitta Henkel, Helmut Sonnenschein
  • Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines for use in treating pain, depression and/or anxiety
    Publication number: 20070203192
    Abstract: Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines=compounds corresponding to formula (I), wherein the various substituents have the meaning provided in the description, and pharmaceutical formulations containing these compounds and methods for producing these compounds and related pharmaceutical formulation, and to methods for treating or inhibiting pain, depression and/or anxiety states.
    Type: Application
    Filed: December 22, 2006
    Publication date: August 30, 2007
    Inventors: Bernd Sundermann, Hagen-Heinrich Hennies, Klaus Schiene, Petra Bloms-Funke, Werner Englberger, Sven Frormann, Derek Saunders
  • NOVEL VANILLOID RECEPTOR LIGANDS AND USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS
    Publication number: 20070105861
    Abstract: The present invention relates to novel vanilloid receptor ligands, to a process for the production thereof, to pharmaceutical preparations containing these compounds and to the use of these compounds for the production of pharmaceutical preparations.
    Type: Application
    Filed: October 19, 2006
    Publication date: May 10, 2007
    Applicant: GRUENENTHAL GMBH
    Inventors: Jeewoo Lee, Hyung Ryu, Robert Frank, Gregor Bahrenberg, Jean De Vry, Thomas Christoph, Derek Saunders, Klaus Schiene, Bernd Sundermann
  • Pharmaceutical compositions containing aryl or heteroaryl azolylcarbinol compounds
    Publication number: 20060194860
    Abstract: Pharmaceutical formulations are provided and comprise compounds corresponding to formula I, wherein R1, R2, R3 and R4 have the meanings given in the description. Related methods of treating or inhibiting pain and other conditions or disorders are also provided.
    Type: Application
    Filed: January 31, 2006
    Publication date: August 31, 2006
    Applicant: GRUENENTHAL GMBH
    Inventors: Clemens Gillen, Thomas Christoph, Klaus Schiene, Derek Saunders, Hagen-Heinrich Hennies, Carsten Griebel
  • Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants
    Publication number: 20060025456
    Abstract: Saturated and unsaturated heteroarylcycloalkylmethyl-amine compounds corresponding to formula I, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of saturated and unsaturated heteroarylcycloalkylmethyl-amines for the preparation of pharmaceutical formulations. pharmaceutical formulations and related methods of treatment or prophylaxis of certain condition, especially depression and/or pain, are also disclosed.
    Type: Application
    Filed: June 20, 2005
    Publication date: February 2, 2006
    Applicant: Gruenenthal GmbH
    Inventors: Petra Bloms-Funke, Claudia Puetz, Ivars Graudums, Achim Kless, Carsten Griebel, Hagen-Heinrich Hennies, Dagmar Kaulartz, Sabine Reinardy, Derek Saunders, Klaus Schiene, Bernd Sundermann, Werner Englberger, Oswald Zimmer
  • Spirocyclic cyclohexane compounds
    Publication number: 20050192333
    Abstract: Spirocyclic cyclohexane compounds, methods for their production, pharmaceutical compositions containing these compounds, and the use of these spirocyclic cyclohexane compounds for treating conditions associated with the nociceptin/ORL1 receptor system, e.g. pain, drug withdrawal, anxiety, etc.
    Type: Application
    Filed: December 23, 2004
    Publication date: September 1, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Claudia Hinze, Bernd Sundermann, Stefan Oberboersch, Werner Englberger, Elmark Friderichs, Sven Frormann, Babette-Yvonne Koegel, Klaus Linz, Beatrix Merla, Derek Saunders, Wolfgang Schroeder, Hans Schick, Birgitta Henkel, Helmut Sonnenschein
  • 1-Phenyl-2-dimethylaminomethyl cyclohexane compounds and therapies for depressive symptoms, pain and incontinence
    Publication number: 20050182131
    Abstract: The invention relates to metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for producing a medicament used for treating depression, and related methods of treating depression.
    Type: Application
    Filed: January 19, 2005
    Publication date: August 18, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Elmar Friderichs, Wolfgang Strassburger, Ulrich Jahnel, Derek Saunders, Hagen-Heinrich Hennies, Werner Englberger, Helmut Buschmann, Joerg Holenz, Oswald Zimmer