Patents by Inventor Devin V. McAllister

Devin V. McAllister has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180133447
    Abstract: The devices 400, 500 include microneedles 450, 550 that may be separable from the drug delivery devices, control drug release rate and/or direction, or a combination thereof. When the microneedles are separable, a force applied to the drug delivery devices may be effective to penetrate a biological tissue with the microneedles and then to separate the microneedles from the drug delivery devices. The drug delivery devices may be capable of achieving discrete periods of drug release.
    Type: Application
    Filed: April 18, 2016
    Publication date: May 17, 2018
    Inventors: Devin V. McALLISTER, Mark R. PRAUSNITZ, Sebastien HENRY
  • Publication number: 20170035966
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Application
    Filed: October 21, 2016
    Publication date: February 9, 2017
    Applicant: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Patent number: 9561042
    Abstract: The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: February 7, 2017
    Assignee: Valeritas, Inc.
    Inventors: Devin V. McAllister, Ciro DiMeglio
  • Patent number: 9511187
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: December 6, 2016
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Patent number: 9415198
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: August 16, 2016
    Assignee: Valeritas, Inc.
    Inventor: Devin V. McAllister
  • Publication number: 20160101272
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Application
    Filed: October 9, 2015
    Publication date: April 14, 2016
    Inventor: Devin V. McAllister
  • Publication number: 20150328400
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Application
    Filed: July 27, 2015
    Publication date: November 19, 2015
    Applicant: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Patent number: 9155875
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: October 13, 2015
    Assignee: Valeritas, Inc.
    Inventor: Devin V. McAllister
  • Patent number: 9125983
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Grant
    Filed: April 17, 2010
    Date of Patent: September 8, 2015
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Patent number: 9072828
    Abstract: Presently disclosed is a hydraulic pump device and its use thereof, especially in a fluid delivery system. In one embodiment, the fluid delivery system is an inexpensive, single-use device for slow dosing medicament applications. The fluid delivery system may employ a spring-compressed bellows crank or other combination of simple mechanisms operating according to the well-known peristaltic principle to force a volume of ultrapure bio-inert hydraulic fluid through an aperture, thereby expanding one chamber of a two chamber hydraulic cylinder. The second, fluid storage chamber, containing the medicament, is emptied through a conventional orifice in response to the expansion of the pump chamber. The medicament may then flow through any suitable infusion set into a patient removeably attached thereto.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: July 7, 2015
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Patent number: 9011392
    Abstract: The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: April 21, 2015
    Assignee: Valeritas, Inc.
    Inventors: Devin V. McAllister, Ciro DiMeglio
  • Publication number: 20150000788
    Abstract: A vented needle comprises a distal end configured to pierce a seal of a first container having a top and a bottom surface and a seal of a second container having a top and a bottom surface. An interior lumen is configured to fluidly couple the first container and a fluid transfer device and the second container and the fluid transfer device. A middle portion is configured to engage the seals of the first container and the second container and having one or more axially extending vents. At least one of the one or more vents is configured to extend axially past the top and bottom surfaces of the seal of the first container and configured to fluidly couple the first container and ambient air outside the first container. None of the one or more vents are configured to extend axially past top and bottom surfaces of the seal of the second container.
    Type: Application
    Filed: December 12, 2012
    Publication date: January 1, 2015
    Applicant: Valeritas, Inc.
    Inventors: Devin V. McAllister, Daniel W. Connors
  • Patent number: 8734395
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: May 27, 2014
    Assignee: Valeritas, Inc.
    Inventor: Devin V. McAllister
  • Patent number: 8708966
    Abstract: Microneedle devices are provided for transport of molecules across tissue barriers and for use as microflameholders. In a preferred embodiment for transport across tissue, the microneedles are formed of a biodegradable polymer. Methods of making these devices, which can include hollow and/or porous microneedles, are also provided. A preferred method for making a microneedle includes forming a micromold having sidewalls which define the outer surface of the microneedle, electroplating the sidewalls to form the hollow microneedle, and then removing the micromold from the microneedle. In a preferred method of use, the microneedle device is used to deliver material into or across a biological barrier from chambers in connection with at least one of the microneedles. The device preferably further includes a means for controlling the flow of material through the microneedles. Representative examples of these means include the use of permeable membranes, fracturable impermeable membranes, valves, and pumps.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: April 29, 2014
    Assignee: Georgia Tech Research Corporation
    Inventors: Mark G. Allen, Mark R. Prausnitz, Devin V. McAllister, Florent Paul Marcel Cros
  • Publication number: 20130338596
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Application
    Filed: August 21, 2013
    Publication date: December 19, 2013
    Applicant: Valeritas, Inc.
    Inventor: Devin V. McAllister
  • Publication number: 20130338597
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Application
    Filed: August 21, 2013
    Publication date: December 19, 2013
    Applicant: Valeritas, Inc.
    Inventor: Devin V. McAllister
  • Patent number: 8540672
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: September 24, 2013
    Assignee: Valeritas, Inc.
    Inventor: Devin V. McAllister
  • Publication number: 20120184906
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Application
    Filed: December 20, 2011
    Publication date: July 19, 2012
    Inventor: Devin V. McAllister
  • Patent number: 8162901
    Abstract: Microneedle devices for transport of molecules, including drugs and biological molecules, across tissue, are provided. The microneedle devices permit drug delivery or removal of body fluids at clinically relevant rates across skin or other tissue barriers, with minimal or no damage, pain, or irritation to the tissue. Microneedles can be formed of biodegradable or non-biodegradable polymeric materials or metals. In a preferred embodiment, a microneedle device includes a plugging element comprising a platform including a plurality of microneedle plugs for preventing skin or other tissue barriers from entering the hollow microneedles. In another preferred embodiment, a microneedle device includes a plurality of bioerodible elements for temporarily plugging the hollow microneedles, thereby preventing skin or other tissue barriers from entering the hollow microneedles.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: April 24, 2012
    Assignee: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Devin V. McAllister
  • Patent number: 8070726
    Abstract: Presently disclosed is a hydraulic pump device and its use thereof, especially in a fluid delivery system. In one embodiment, the fluid delivery system is an inexpensive, single-use device for slow dosing medicament applications. The fluid delivery system may employ a spring-compressed bellows crank or other combination of simple mechanisms operating according to the well-known peristaltic principle to force a volume of ultrapure bio-inert hydraulic fluid through an aperture, thereby expanding one chamber of a two chamber hydraulic cylinder. The second, fluid storage chamber, containing the medicament, is emptied through a conventional orifice in response to the expansion of the pump chamber. The medicament may thence flow through any suitable infusion set into a patient removeably attached thereto.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: December 6, 2011
    Assignee: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque