Patents by Inventor Dieter Jaworek

Dieter Jaworek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4367072
    Abstract: Method for the determination of a component in a liquid which component is selected from ions, polar substances lipophilic substances, which comprises contacting a liquid sample containing said component with, and allowing same to act upon, a complex ligand or host molecule which is selective toward the component, said complex ligand or host molecule being bonded to a chromophore material, and measuring the change of extinction or the wavelength displacement of the resulting mixture as a measure of the initial content of said component; corresponding reagent test kits are also provided. The complex ligands or host molecules include cyclodextrins, cyclophanes, crown ethers, cryptands, podands valinomycin, gramacidin and monactin.
    Type: Grant
    Filed: September 25, 1979
    Date of Patent: January 4, 1983
    Assignee: Boehringer Mannheim GmbH
    Inventors: Friedrich Vogtle, Johannes P. Dix, Dieter Jaworek
  • Patent number: 4119589
    Abstract: Biologically active proteins are immobilized onto a carrier by reacting a compound containing at least two secondary amino groups at a temperature of from to C with a chlorination agent with the conversion of the secondary amino groups into iminochloride groups of the formula ##STR1## in which R and R.sub.1, which can be the same or different, are aliphatic, aromatic or aliphatic-aromatic radicals, and reacting the carrier material product thus obtained(a) directly with a biologically-active protein, in an aqueous solvent, or(b) with a bifunctional compound containing at least one primary amino group, optionally in an aqueous or organic solvent, and reacting the product thereby obtained containing groups of the formula ##STR2## in which R.sub.2 is an alkylene radical, an .alpha.,.omega.
    Type: Grant
    Filed: January 18, 1977
    Date of Patent: October 10, 1978
    Assignee: Boehringer Mannheim GmbH
    Inventors: Jurgen Horn, Hans-Georg Batz, Dieter Jaworek
  • Patent number: 4081329
    Abstract: Carrier-bound macromolecular compounds, especially bioactive macromolecular compounds, are produced by reacting a macromolecular compound A with a coupling compound B containing at least one reactive function capable of coupling with compound A and at least one further reactive function capable of polymerization, adding to the resulting coupled reaction product AB an unswollen molecular sieve material having cross-linking sufficient to exclude penetration by compound A, and polymerizing the polymerizable group of the coupled product AB in the molecular sieve material to form a polymer body in the molecular sieve material and fix compound A on the surface of the molecular sieve material. Compound A can be, e.g., an enzyme, antibody or hormone, and coupling compound B typically contains, as the coupable function, an alkylation or acylation group such as oxirane, ethyleneimine, halide, acid halide, azide or anhydride groups, and, as the polymerizable function, a carbon-carbon or carbon-oxygen double bond.
    Type: Grant
    Filed: February 5, 1976
    Date of Patent: March 28, 1978
    Assignee: Boehringer Mannheim GmbH
    Inventors: Dieter Jaworek, Karl-Heinz Botsch, Gunter Weimann, Michael Nelbock-Hochstetter, Helmut Determann
  • Patent number: 4038140
    Abstract: Biologically active proteins are bound onto an insoluble carrier by reacting such protein in an aqueous phase with a carrier comprising an activated polysaccharide having a hydrophilic graft co-polmyer grafted thereinto.
    Type: Grant
    Filed: May 30, 1975
    Date of Patent: July 26, 1977
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Dieter Jaworek, Joseph Maier, Michael Nelbock-Hochstetter
  • Patent number: 3969287
    Abstract: Carrier-bound proteins are prepared by reacting a protein in aqueous solution with a coupling compound having at least one group capable of acylating or alkylating proteins and at least one additional group capable of producing a bond with a carrier material, and reacting the resulting product with a carrier material, optionally forming the carrier material in situ by polymerization of a monomer or monomer mixture in the presence of said product.
    Type: Grant
    Filed: November 30, 1973
    Date of Patent: July 13, 1976
    Assignee: Boehringer Mannheim GmbH
    Inventors: Dieter Jaworek, Michael Nelbock-Hochstetter, Klaus Beaucamp, Hans Ulrich Bergmeyer, Karl-Heinz Botsch
  • Patent number: 3935071
    Abstract: Glucose is converted into gluconic acid by oxidation with oxygen in aqueous solution, by a process comprising passing a glucose containing aqueous solution over a catalyst which contains glucose oxidase and catalase, bound to an appropriate carrier, in immediate proximity to one another. The process avoids the disadvantage of previous catalytic processes depending on catalysts which rapidly lose their activity and is adapted to large-scale operation.
    Type: Grant
    Filed: March 13, 1973
    Date of Patent: January 27, 1976
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Hans Ulrich Bergmeyer, Dieter Jaworek