Abstract: Isolated, substantially pure natural or synthetic polypeptides comprising cathepsin L type cysteine proteases, or polypeptide fragments or polypeptide admixtures obtained via proteolysis thereof, are useful for reducing intercorneocyte cohesion and, thus, for promoting desquamation.

Abstract: 2-oxothiazolidine-4-carboxylic acid compounds having the structural formula (I): 1

Abstract: Aminosulfonic acid compounds having the structural formula (I): 1

Abstract: The invention relates to compounds corresponding to formula (I) below: 1

Abstract: The present invention concerns compositions suitable for topical application, comprising glucosylated hydroxystilbenes. It also concerns a method for slowly releasing hydroxystilbenes into the stratum corneum, by applying a composition comprising glucosylated hydroxystilbenes as a precursor. Finally, it concerns the use of glucosylated hydroxystilbenes to combat signs of cutaneous and hair follicle ageing, to improve the radiance of the skin, to smooth the skin of the face, to treat or prevent wrinkles and fine lines in the skin or to stimulate the epidermal renewal process.

Abstract: The invention relates to a cored wire for introducing additives into a molten metal bath comprising a metallic sheath (5) containing an additive (6), which metallic sheath is covered by a wrapping (7) which, being combustible without leaving harmful residues, momentarily retards the propagation of heat to the core of the cored wire, this cored wire being characterized in that on top of this combustible wrapping, a protective metallic casing encloses the assembly thus constituted by the additive, the metallic sheath and the combustible wrapping.

Abstract: Isolated, substantially pure natural or synthetic polypeptides comprising cathepsin L type cysteine proteases, or polypeptide fragments or polypeptide admixtures obtained via proteolysis thereof, are useful for reducing intercorneocyte cohesion and, thus, for promoting desquamation.

Abstract: A cathepsin L type cysteine protease has been isolated from the healthy stratum corneum of human skin. The protease has a pH optimum of 5 to 5.5 and mass of about 28 kDa.

Abstract: A stabilized composition capable of releasing an active agent in contact with the skin, contains at least two precursors of this same active agent, capable of simultaneously releasing this active agent by at least two different specific enzymatic reactions in order to release a large amount of active agent at a faster rate than the sum of the rates of the first enzymatic reaction and of the second enzymatic reaction taken separately, the first precursor being chosen from active agent monosaccharide derivatives and active agent amides. The composition is useful for dermatological and/or cosmetic treatments applied topically.

Abstract: The invention relates to a stabilized, cosmetically and/or dermatologically acceptable emulsion intended to moisturize the skin. This emulsion contains a fatty phase, an aqueous phase, at least one emulsifying agent and at least one moisturizing agent. The aqueous phase contains at least one phosphated compound capable of releasing, via an enzymatic reaction when it is in contact with the skin, an active agent other than the moisturizing agent, which promotes moisturization of the skin, and the fatty phase contains at least one silicone-containing gum and/or one perfluoro oil. The emulsion according to the invention makes it possible to combat ageing of the skin, acne, pigmentation of the skin and/or hair loss.

Abstract: This biosensor comprises a membrane (8), in which an enzyme catalyzing the transformation of a substrate used in the cutaneous metabolism is immobilized, means for detecting and measuring a phenomenon caused by said transformation, which is representative of the concentration of the substrate to be measured, with said substrate being brought into contact with the enzymatic membrane (8), and a measuring cell (13), a wall area of which is formed by the membrane (8) and which is capable of being closed, during the measurement, by a cutaneous covering area (15), with the cell (13) being combined with means for making circulate therein a liquid for placing in solution the substrate to be measured. For the measurement, the biosensor is applied to the skin, the buffer is injected into the cell and, once said cell is filled, the detection and the measurement are carried out, then the buffer is again made to circulate in order to remove the solubilized substrate.