Patents by Inventor Dominique Joubert

Dominique Joubert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180022802
    Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
    Type: Application
    Filed: March 6, 2017
    Publication date: January 25, 2018
    Inventors: Julie PANNEQUIN, Laure Boudier, Dominique Joubert, Frédéric Hollande
  • Publication number: 20170306011
    Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
    Type: Application
    Filed: March 6, 2017
    Publication date: October 26, 2017
    Inventors: Julie PANNEQUIN, Laure Boudier, Dominique Joubert, Frédéric Hollande
  • Publication number: 20170306012
    Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
    Type: Application
    Filed: March 6, 2017
    Publication date: October 26, 2017
    Inventors: Julie PANNEQUIN, Laure Boudier, Dominique Joubert, Frédéric Hollande
  • Publication number: 20170233469
    Abstract: The present disclosure provides methods and compositions useful for preventing gastrointestinal and/or colorectal cancer in animals, including humans, having pre-cancerous adenomatous polyps. The present disclosure provides compositions comprising anti-PG antibodies suitable for use in the methods of the disclosure. The present disclosure also provides methods and compositions useful for monitoring the efficacy of anti-PG treatment in subjects with pre-cancerous polyps.
    Type: Application
    Filed: September 28, 2016
    Publication date: August 17, 2017
    Inventors: Leila HOUHOU, Mathieu PETREMANN, Dominique JOUBERT, Frédéric HOLLANDE
  • Publication number: 20170174761
    Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
    Type: Application
    Filed: March 6, 2017
    Publication date: June 22, 2017
    Inventors: Julie PANNEQUIN, Laure BOU DIER, Dominique JOUBERT, Frédéric HOLLANDE
  • Patent number: 9611320
    Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: April 4, 2017
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), LES LABORATOIRES SERVIER
    Inventors: Julie Pannequin, Laure Boudier, Dominique Joubert, Frédéric Hollande
  • Patent number: 9487582
    Abstract: The present disclosure is directed to methods of treating pancreatic cancer in subject using cancer with antibodies that specifically bind to progastrin.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: November 8, 2016
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), LES LABORATORIES SERVIER
    Inventors: Leïla Houhou, Dominique Joubert, Frédéric Hollande
  • Patent number: 9217032
    Abstract: The present disclosure is directed to methods of treating and preventing colorectal cancer metastasis or recurrence of colorectal cancer with compositions comprising anti-progastrin antibodies.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: December 22, 2015
    Assignee: LES LABORATOIRES SERVIER
    Inventors: Julie Pannequin, Leïla Houhou, Bérénice Framery, Nejla Erkilic, Dominique Joubert, Frédéric Hollande
  • Publication number: 20150071912
    Abstract: The present disclosure provides methods and compositions useful for preventing gastrointestinal and/or colorectal cancer in animals, including humans, having pre-cancerous adenomatous polyps. The present disclosure provides compositions comprising anti-PG antibodies suitable for use in the methods of the disclosure. The present disclosure also provides methods and compositions useful for monitoring the efficacy of anti-PG treatment in subjects with pre-cancerous polyps.
    Type: Application
    Filed: March 23, 2011
    Publication date: March 12, 2015
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Lelïa Houhou, Mathieu Petremann, Dominique Joubert, Frédéric Hollande
  • Publication number: 20150038357
    Abstract: Disclosed is a method of determining the survival prognosis of a patient afflicted by a glioma. The method includes assessing the level of expression of one or more specific gene in cells of the glioma.
    Type: Application
    Filed: October 1, 2012
    Publication date: February 5, 2015
    Inventors: Dominique Joubert, Luc Bauchet, Jean-Philippe Hugnot, Ivan Bieche, Rosette Lidereau, Thierry Reme, Hugues Duffau, Valerie Rigau
  • Patent number: 8900588
    Abstract: The present disclosure is directed to methods of treating and preventing breast cancer or recurrence of breast cancer with compositions comprising anti-progastrin antibodies.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: December 2, 2014
    Assignees: Les Laboratories Servier, Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS)
    Inventors: Jean-François Floch, Leïla Houhou, Françoise Cailler, Dominique Joubert, Frédéric Hollande
  • Publication number: 20140005249
    Abstract: The present invention relates to NKX2.2 inhibitors such as shRNAs for treating pathologies.
    Type: Application
    Filed: July 21, 2011
    Publication date: January 2, 2014
    Applicants: UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER, INSTITUT CURIE
    Inventors: Jean-Philippe Hugnot, Pierre-Olivier Guichet, Marisa Teigell, Ivan Bieche, Rosette Lidereau, Dominique Joubert, Luc Bauchet, Valerie Rigau
  • Publication number: 20120020961
    Abstract: The present disclosure provides methods of treating liver cancer and preventing liver cancer recurrence with anti-progastrin antibodies, methods of monitoring treatment efficacy of anti-progastrin therapy for liver cancer, and compositions useful therefore.
    Type: Application
    Filed: July 22, 2011
    Publication date: January 26, 2012
    Inventors: Leila Houhou, Anne-Sophie Dumé, Dominique Joubert, Frédéric Hollande
  • Publication number: 20110177062
    Abstract: The present disclosure is directed to methods of treating and preventing breast cancer or recurrence of breast cancer with compositions comprising anti-progastrin antibodies.
    Type: Application
    Filed: January 4, 2011
    Publication date: July 21, 2011
    Inventors: Jean-François Floch, Leïla Houhou, Françoise Cailler, Dominique Joubert, Frédéric Hollande
  • Publication number: 20110177063
    Abstract: The present disclosure is directed to methods of treating and preventing colorectal cancer metastasis or recurrence of colorectal cancer with compositions comprising anti-progastrin antibodies.
    Type: Application
    Filed: January 4, 2011
    Publication date: July 21, 2011
    Applicants: BIOREALITES, S.A.S., INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Julie Pannequin, Leïla Houhou, Bérénice Framery, Nejla Erkilic, Dominique Joubert, Frédéric Hollande
  • Publication number: 20110171213
    Abstract: The present disclosure is directed to methods of treating pancreatic cancer in subject using cancer with antibodies that specifically bind to progastrin.
    Type: Application
    Filed: January 4, 2011
    Publication date: July 14, 2011
    Inventors: Leïla Houhou, Dominique Joubert, Frédéric Hollande
  • Publication number: 20110117086
    Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
    Type: Application
    Filed: October 15, 2010
    Publication date: May 19, 2011
    Applicants: BIORÉALITÉS S.A.S., INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: JULIE PANNEQUIN, LAURE BOUDIER, DOMINIQUE JOUBERT, FRÉDÉRIC HOLLANDE
  • Publication number: 20100209426
    Abstract: The present invention relates to inhibitors of progastrin induced repression of ICAT for treating and/or preventing colorectal cancer, adenomatous polyposis or metastasis displaying progastrin-secreting cells and cells in which the beta-catenin/Tcf-4-mediated transcriptional pathway is constitutively active.
    Type: Application
    Filed: May 21, 2007
    Publication date: August 19, 2010
    Applicants: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA REC HERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERECHE SCIENTIFIQUE- CNRS, UNIVERSITE DE MONTPELLIER 1
    Inventors: Frederic Hollande, Dominique Joubert, Philippe Jay, Julie Pannequin, Nathalie Delaunay, Jean-Francois Bourgaux
  • Patent number: 5685975
    Abstract: A water softening device includes a cylindrical housing with an inlet formed at one end for admitting water to be treated. A filtering material is located in an upstream zone adjacent the inlet. A plate is positioned in relative spaced relation to an opposite end of the housing. A downstream zone, free of filtering material, is located between the plate and the opposite end. Openings are formed in the plate to allow passage of softened water to flow between the upstream and downstream zones. A conduit is axially located in the housing and has a first open end communicating with the downstream zone. A second end of the conduit forms an outlet of the device. A check valve is located at the first end of the conduit for allowing unidirectional flow of water undergoing softening from the downstream zone to the conduit, the check valve restricting flow between the zones during brine regeneration.
    Type: Grant
    Filed: September 11, 1996
    Date of Patent: November 11, 1997
    Assignee: BWT France
    Inventors: Dominique Joubert, Michel Pecolatto, Martial Sabatier, Veronique Tharreau, Jean Michel Arribard