Abstract: The invention provides methods for the diagnosis and treatment of musculoskeletal disorders relating to the Hedgehog pathway, including but not limited to muscular dystrophy (e.g., Duchenne Muscular Dystrophy) using agents that agonize Sonic Hedgehog (shh), and thereby, the Hedgehog signaling pathway. Said agonizing agents include, e.g., the compounds of the invention (e.g., a compound of Formula I). The invention also provides methods of screening for agents that are capable of increasing the proliferation of muscle and/or muscle precursor cells.

Abstract: An apparatus, program product and method effectively virtualize a hardware device shared between multiple processors by a file accessible by a processor such that access to the hardware device may be controlled via a lock associated with the file. By doing so, file-based locking, e.g., as provided by a file locking facility in an operating system running on a processor, may be used to control access to the hardware device on behalf of the processor.

Abstract: The aspects of the present invention provide a computer implemented method, an apparatus, and a computer usable program code for identifying a service processor with current setting information. First stored information for a service processor is retrieved from a first memory in the first service processor. Second stored information for the service processor is retrieved from a second memory in a data processing system to which the service processor is connected. The first stored information is compared with the second stored information to form a comparison as to whether the service processor was previously connected to the data processing system and to determine whether the service processor was a last service processor to fully communicate with system firmware in the data processing system. The service processor has current setting information if the service processor was previously connected to the data processing system and was the last service processor to fully communicate with the system firmware.

Abstract: The present disclosure concerns specific Pseudomonas fluorescens and Pseudomonas putida strains, specific genes and their corresponding specific gene products, the specific bioherbicide molecules whose synthesis or secretion is controlled by those genes and gene products, and methods of using these molecules to control deleterious weeds.

Abstract: The present disclosure concerns specific Pseudomonas fluorescens and Pseudomonas putida strains, specific genes and their corresponding specific gene products, the specific bioherbicide molecules whose synthesis or secretion is controlled by those genes and gene products, and methods of using these molecules to control deleterious weeds.

Abstract: A product branding apparatus and methods as disclosed relate to a branding element having indicia configured in the shape of a desired design to be branded onto a product and a heating conductor for transferring heat from a heating apparatus to the branding element.

Abstract: A concise linked document language, a computer network client interpreting the concise linked document language, and exemplary applications using the concise linked document language. The concise linked document language incorporates features which allow presentation, acquisition, and document links using a distributed client composed of a computer network device linked via a communications link to an information device. The distributed client can be used to access servers located on a computer network from almost any information device creating a pervasive computer networking environment. The features of the concise linked document language allow rapid construction and deployment of Internet based applications which are extended by existing communications links such as a voice/email system where the native email documents may be presented as either text or voice depending on the presentation capabilities of the information device.

Abstract: A concise linked document language, a computer network client interpreting the concise linked document language, and exemplary applications using the concise linked document language. The concise linked document language incorporates features which allow presentation, acquisition, and document links using a distributed client composed of a computer network device linked via a communications link to an information device. The distributed client can be used to access servers located on a computer network from almost any information device creating a pervasive computer networking environment. The features of the concise linked document language allow rapid construction and deployment of Internet based applications which are extended by existing communications links such as a voice/email system where the native email documents may be presented as either text or voice depending on the presentation capabilities of the information device.

Abstract: The present invention provides a method for determining the amount of HIV-1 p24 antigen or anti-HIV-1 p24 antibody present in a suitable bodily fluid sample from an HIV-1-infected subject. This invention also provides a kit for determining the amount of HIV-1 p24 antigen or anti-HIV-1 p24 antibody present in an HIV-1-infected subject.

Abstract: Pneumocystis carinii pneumonia may be prevented in a subject susceptible to infection by Pneumocystis carinii by administering to the subject an amount of a pentamidine in aerosol form effective to prevent infection by Pneumocystis carinii and thus prevent Pneumocystis carinii pneumonia. Also, this invention provides a composition for the prevention of Pneumocystis carinii pneumonia which comprises an amount of a pentamidine effective to prevent infection by Pneumocystis carinii and thus prevent Pneumocystis carinii pneumonia in aerosol form and a pharmaceutically acceptable carrier.

Abstract: This invention concerns a method of preventing a pulmonary infection by a fungus in a subject susceptible to infection by the fungus comprising administering to the subject an amount per dose in an aerosol spray of a polyene or a pharmaceutically acceptable derivative thereof, effective to prevent pulmonary infection by the fungus. This invention further discloses a method of treating pulmonary aspergillosis in a subject comprising administering to the subject an amount per dose in an aerosol spray of a polyene, e.g., amphotericin B or pimaricin, or a pharmaceutically acceptable derivative thereof effective to treat aspergillosis.

Abstract: A "passive interrogator label system" (PILS) is disclosed with passive, SAW transponders which are capable of receiving an interrogation signal, processing this signal and transmitting a reply signal that is derived from the interrogation signal and contains encoded information. The SAW transducers employed in the transponders are operated at their third harmonic and comprise split fingers which reduce SAW reflections. These transducers are also shaped to increase their bandwidth and to reduce their capacitance. The bus bars connecting the transducers are formed of double thickness to reduce ohmic resistance losses and these bus bars as well as the transponder phase delay pads have two levels of serrations on their edges to substantially cancel reflections. SAW reflectors in the transponder are provided with shorts between successive fingers to reduce ohmic resistance losses and to render them less susceptible to fabrication errors.

Abstract: A "passive interrogator label system" (PILS) comprises an interrogator for transmitting an interrogation signal, one or more "labels" or passive transponders which produce a reply signal containing coded information in response to the interrogation signal, and a receiver and decoder for receiving the reply signal and decoding the information contained in it. The frequency of the interrogation signal assumes a plurality of frequency values within a prescribed frequency range. The decoder includes a mixer (4 quadrant multiplexer) for mixing together the interrogation and reply signals (or signals derived therefrom) to produce a further signal containing frequencies which are the sum and difference of the interrogation and reply signals. A signal processor, responsive to this further signal produced by the mixer, detects at least some of the frequencies contained in this further signal and determines the informational code associted with the transponder.