Patents by Inventor Donald D. Muccio

Donald D. Muccio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL REXINOID COMPOUNDS AND METHODS OF USING REXINOID COMPOUNDS FOR TREATING METABOLIC DISORDERS AND CANCER
    Publication number: 20210101861
    Abstract: Novel rexinoid compounds are provided herein. Also provided herein are methods of using the compounds to treat disorders, such as metabolic disorders, diabetes, insulin resistance, glucose intolerance, obesity, steatosis, inflammation, and/or cancer.
    Type: Application
    Filed: September 18, 2020
    Publication date: April 8, 2021
    Applicant: THE UAB RESEARCH FOUNDATION
    Inventors: Donald D. Muccio, Venkatram Reddy Atigadda, Wayne J. Brouillette, Clinton J. Grubbs, Jeonga Kim
  • Rexinoid compounds and methods of using rexinoid compounds for treating metabolic disorders and cancer
    Patent number: 10800726
    Abstract: Novel rexinoid compounds are provided herein. Also provided herein are methods of using the compounds to treat disorders, such as metabolic disorders, diabetes, insulin resistance, glucose intolerance, obesity, steatosis, inflammation, and/or cancer.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: October 13, 2020
    Assignee: THE UAB RESEARCH FOUNDATION
    Inventors: Donald D. Muccio, Venkatram Reddy Atigadda, Wayne J. Brouillette, Clinton J. Grubbs, Jeonga Kim
  • NOVEL REXINOID COMPOUNDS AND METHODS OF USING REXINOID COMPOUNDS FOR TREATING METABOLIC DISORDERS AND CANCER
    Publication number: 20180201565
    Abstract: Novel rexinoid compounds are provided herein. Also provided herein are methods of using the compounds to treat disorders, such as metabolic disorders, diabetes, insulin resistance, glucose intolerance, obesity, steatosis, inflammation, and/or cancer.
    Type: Application
    Filed: June 30, 2015
    Publication date: July 19, 2018
    Applicant: THE UAB RESEARCH FOUNDATION
    Inventors: Donald D. Muccio, Venkatram Reddy Atigadda, Wayne J. Brouillette, Clinton J. Grubbs, Jeonga Kim
  • METHODS FOR MAKING RETINOIDS AND USES THEREOF
    Publication number: 20160106697
    Abstract: Described herein are methods for making retinoids. Also described herein are retinoids and methods of use thereof.
    Type: Application
    Filed: September 21, 2015
    Publication date: April 21, 2016
    Applicant: THE UAB RESEARCH FOUNDATION
    Inventors: Wayne J. Brouillette, Donald D. Muccio, Venkatram Reddy Atigadda, John M. Ruppert, Susan M. Lobo Ruppert
  • Methods for making retinoids and uses thereof
    Patent number: 9169190
    Abstract: Described herein are methods for making retinoids. Also described herein are retinoids and methods of use thereof.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: October 27, 2015
    Assignee: The UAB Research Foundation
    Inventors: Wayne J. Brouillette, Donald D. Muccio, Venkatram Reddy Atigadda, John M. Ruppert, Susan M. Lobo Ruppert
  • RETINOIDS AND USE THEREOF
    Publication number: 20150202174
    Abstract: The present invention provides new retinoid compounds and uses of the compounds in humans and animals for non-neoplastic dermal or inflammatory conditions or disorders.
    Type: Application
    Filed: July 1, 2013
    Publication date: July 23, 2015
    Inventors: Wayne J. Brouillette, Donald D. Muccio, Venkatram Reddy Atigadda, John M. Ruppert, Susan M. Lobo Ruppert
  • RETINOIDS AND USE THEREOF
    Publication number: 20140057982
    Abstract: The present invention provides new retinoid compounds and uses of the compounds in humans and animals for non-neoplastic dermal or inflammatory conditions or disorders.
    Type: Application
    Filed: July 1, 2013
    Publication date: February 27, 2014
    Applicant: THE UAB RESEARCH FOUNDATION
    Inventors: Wayne J. Brouillette, Donald D. Muccio, Venkatram Reddy Atigadda, John M. Ruppert, Susan M. Ruppert
  • METHODS FOR MAKING RETINOIDS AND USES THEREOF
    Publication number: 20130317106
    Abstract: Described herein are methods for making retinoids. Also described herein are retinoids and methods of use thereof.
    Type: Application
    Filed: April 4, 2013
    Publication date: November 28, 2013
    Applicant: The UAB Research Foundation
    Inventors: Wayne J. Brouillette, Donald D. Muccio, Venkatram Reddy Atigadda, John M. Ruppert, Susan M. Lobo Ruppert
  • Retinoids and use thereof
    Patent number: 8475775
    Abstract: The present invention provides new retinoid compounds and uses of the compounds in humans and animals for non-neoplastic dermal or inflammatory conditions or disorders.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: July 2, 2013
    Assignee: The UAB Research Foundation
    Inventors: Wayne J. Brouillette, Donald D. Muccio, Venkatram Reddy Atigadda, John M. Ruppert, Susan M. Ruppert
  • Retinoids and use thereof
    Patent number: 6172112
    Abstract: The present invention provides new retinoid compounds and uses of the compounds in humans and animals for chemoprevention of skin and/or breast cancer and for therapy of leukemia.
    Type: Grant
    Filed: April 6, 1999
    Date of Patent: January 9, 2001
    Assignee: UAB Research Foundation
    Inventors: Wayne J. Brouillette, Donald D. Muccio
  • Retinoid compounds
    Patent number: 5094783
    Abstract: Retinoid compounds with bioactive properties and their synthesis are described. The compounds are useful as chemopreventive or cancer-treating agents and dermatological agents. The novel retinoids are members of either of the two general structures: ##STR1## wherein X is CO.sub.2 H or CH.sub.2 OH; and in formula (I), R.sub.1 and R.sub.2 are each hydrogen, a C.sub.1-4 alkyl, a C.sub.1-4 alkoxy, or R.sub.1 and R.sub.2 taken together form a 5- to 7-membered cycloalkyl or cycloalkenyl ring; and in formula (II), R.sub.1 and R.sub.2 are each hydrogen, a C.sub.1-4 alkyl, a C.sub.1-4 alkenyl or a C.sub.1-4 alkoxy, or R.sub.2 and R.sub.3 taken together form a 5- to 7-membered cycloalkyl or cycloalkenyl with R.sub.1 and R.sub.4 being a hydrogen atom, a C.sub.1-4 alkyl, a C.sub.1-4 alkenyl or a C.sub.1-4 alkoxy.
    Type: Grant
    Filed: June 29, 1990
    Date of Patent: March 10, 1992
    Assignee: UAB Research Foundation
    Inventors: Donald D. Muccio, Wayne J. Brouillette