Patents by Inventor Donald E. Kuhla

Donald E. Kuhla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic benzenoid alkylene amino thieno[3,4-d]isothiazole ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4699906
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: May 23, 1986
    Date of Patent: October 13, 1987
    Assignee: Rorer Pharmaceutical Corporation
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4692445
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: November 12, 1986
    Date of Patent: September 8, 1987
    Assignee: Rorer Pharmaceutical Corporation
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Heterocyclic guanidines for treating gastrointestinal motility dysfunction
    Patent number: 4689335
    Abstract: A method for treating gastrointestinal motility dysfunctions using phenylheterocyclic guanidines and novel heterocyclic guanidine compounds.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: August 25, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
  • Bicycle benzo-oxy heterocyclic ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4668673
    Abstract: A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: July 2, 1986
    Date of Patent: May 26, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt, Kent W. Neuenschwander
  • Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4647559
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: May 23, 1986
    Date of Patent: March 3, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Benzocyclobutene aminoalkylene ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4639442
    Abstract: A class of benzocyclobutene aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: November 1, 1985
    Date of Patent: January 27, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4638001
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: April 27, 1984
    Date of Patent: January 20, 1987
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
    Patent number: 4632927
    Abstract: A class of bicyclic nitrogen heterocyclic ether and thioether compounds exhibiting pharmacological activity including cytoprotective, H.sub.2 -antagonist, anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
    Type: Grant
    Filed: March 20, 1984
    Date of Patent: December 30, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Henry F. Campbell, Donald E. Kuhla, William L. Studt, Stuart A. Dodson
  • Antisecretory bicyclic benzo-oxy heterocyclic ethers and thioethers
    Patent number: 4612309
    Abstract: A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastro-intestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: October 23, 1984
    Date of Patent: September 16, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt, Kent W. Neuenschwander
  • 3- and 5-[bicyclic ether or bicyclic alkylene thioether]alkylene amino thiatriazines, and their pharmaceutical uses
    Patent number: 4595683
    Abstract: A class of 3- and 5-amino thiatriazine compounds exhibiting pharmacological activity, including gastrointestinal anti-ulcerogenic and cytoprotective activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: October 23, 1984
    Date of Patent: June 17, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt, Stuart A. Dodson
  • Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4588719
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
    Type: Grant
    Filed: October 24, 1984
    Date of Patent: May 13, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: William L. Studt, Donald E. Kuhla, Henry F. Campbell
  • Quinoline and quinazoline derivatives for treating gastrointestinal motility dysfunctions
    Patent number: 4563460
    Abstract: A method for treating gastrointestinal motility dysfunctions using 2-amino-quinoline and -quinazoline derivatives.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: January 7, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
  • 1,2,4-Triazines for treating gastrointestinal motility dysfunction
    Patent number: 4563456
    Abstract: Method for treating gastrointestinal motility dysfunctions using 1,2,4-triazines.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: January 7, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
  • Guanidine derivatives for treating gastrointestinal motility dysfunction
    Patent number: 4563475
    Abstract: A method for the treatment of a gastrointestinal motility dysfunction using a nitrogen containing heterocyclyl substituted acetylguanidine.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: January 7, 1986
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
  • Triazinones for treating irritable bowel syndrome
    Patent number: 4562188
    Abstract: A method for the treatment of irritable bowel syndrome using a 1,3,5-triazin-2-one and a class of 6-amino and 6-mercaptyl-1,3,5-triazin-2-one compounds.
    Type: Grant
    Filed: January 13, 1984
    Date of Patent: December 31, 1985
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
  • Process for preparing 2-methyl-2-hydroxypropyl piperazine-1-carboxylate compounds
    Patent number: 4550164
    Abstract: Isobutylene carbonate and certain 1-substituted piperazine compounds are reacted in a process that forms 2-methyl-2-hydroxypropyl 4-substituted piperazine-1-carboxylate compounds which are medicinal agents or synthetic intermediates for such agents. The features of the process allow the preparation of an essentially pure 2-methyl-2-hydroxypropyl carboxylate compound.
    Type: Grant
    Filed: April 24, 1981
    Date of Patent: October 29, 1985
    Assignee: Pfizer Inc.
    Inventors: Irving M. Goldman, Donald E. Kuhla, Constantine Sklavounos
  • Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses
    Patent number: 4543352
    Abstract: A class of naphthalene aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
    Type: Grant
    Filed: April 29, 1983
    Date of Patent: September 24, 1985
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
    Patent number: 4529723
    Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
    Type: Grant
    Filed: April 29, 1983
    Date of Patent: July 16, 1985
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
    Patent number: 4520025
    Abstract: A class of bicyclic nitrogen heterocyclic ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
    Type: Grant
    Filed: July 21, 1982
    Date of Patent: May 28, 1985
    Assignee: William H. Rorer, Inc.
    Inventors: Henry F. Campbell, Donald E. Kuhla, William L. Studt, Stuart A. Dodson
  • Treatment of coccidiosis
    Patent number: 4486439
    Abstract: A method for the preventive and curative treatment of coccidial infections in humans and other animals comprising the administration thereto of an amidinourea of amidinothiourea.
    Type: Grant
    Filed: September 16, 1982
    Date of Patent: December 4, 1984
    Assignee: William H. Rorer, Inc.
    Inventors: William L. Studt, Donald E. Kuhla, Billy J. Chou, John Yelnosky