Patents by Inventor Donald F. Worth

Donald F. Worth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4604390
    Abstract: Substituted 2H-[1]benzopyrano[4,3,2-cd]indazoles, 2H-[1]benzothiopyrano[4,3,2-cd]indazoles, and 2H-[1]benzoselenino[4,3,2-cd]indazoles have demonstrated pharmacological activity against a broad spectrum of Gram-positive and Gram-negative bacteria, yeasts, and fungi, as well as activity against the L1210 and P388 murine leukemia cells lines.Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating bacterial or fungal infections and of inhibiting the growth of neoplasms in mammals are also disclosed.
    Type: Grant
    Filed: May 24, 1985
    Date of Patent: August 5, 1986
    Assignee: Warner-Lambert Company
    Inventors: Edward F. Elslager, Leslie M. Werbel, Daniel F. Ortwine, Donald F. Worth, Howard D. H. Showalter, David B. Capps, Ellen M. Berman, Vlad E. Gregor, Anthony D. Sercel
  • Patent number: 4582851
    Abstract: 1,4-Aminoalkylamino-9H-thioxanthen-9-ones have antimicrobial activity and activity against leukemic cells. Methods for their preparation, use and pharmaceutical compositions are described.
    Type: Grant
    Filed: January 10, 1985
    Date of Patent: April 15, 1986
    Assignee: Warner-Lambert Company
    Inventor: Donald F. Worth
  • Patent number: 4515793
    Abstract: A compound of the formula ##STR1## in which A is ##STR2## n is 1, 2 or 3, and R is phenyl optionally substituted with halogen, alkyl, phenyl, cyano, hydroxy, alkoxy, mercapto, sulfinyl, sulfonyl, amino, nitro, trifluoromethyl and/or naphthyl radicals; or a furan, thiophene, pyridine, benzofuran, dibenzothiophene or thianthrene radical,or a pharmacologically acceptable salt thereof, for treating schistosomiasis.
    Type: Grant
    Filed: July 27, 1983
    Date of Patent: May 7, 1985
    Assignee: Edna McConnell Clark Foundation
    Inventors: Leslie M. Werbel, Norman Colbry, William Turner, Donald F. Worth
  • Patent number: 4234583
    Abstract: 2-Chloro-4-(4-lower alkyl-1-piperazinyl)benzenemethanol, N.sup..omega. -oxides and their acid addition salts. These compounds are prepared by oxidizing the corresponding 2-chloro-4-(4-lower alkyl-1-piperazinyl)benzenemethanol. In addition, pharmaceutical compositions comprising said N-oxides and methods for treating schistosomiasis are disclosed.
    Type: Grant
    Filed: November 30, 1978
    Date of Patent: November 18, 1980
    Assignee: Edna McConnell Clark Foundation
    Inventors: Ernest Bueding, Leslie M. Werbel, Donald F. Worth