Patents by Inventor Donald L. Herber

Donald L. Herber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing suspensions of low-solubility materials
    Patent number: 9775802
    Abstract: A process for producing a pharmaceutical suspension that comprises an active pharmaceutical ingredient (“API”) having low solubility, the process comprises: (a) preparing a first solution comprising a carboxy-containing vinyl polymer and a solvent; and (b) adding a compound of the API to said first solution under conditions of high-shear mixing for a time from about 5 minutes to about 5 hours, said compound being soluble in said solvent, thereby producing a suspension of particles of said API in a composition comprising said carboxy-containing vinyl polymer; wherein a concentration of said API in said suspension is higher than a solubility of said API in said solvent. The present invention also provides a suspension produced by such process.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: October 3, 2017
    Assignee: Bausch & Lomb Incorporated
    Inventors: Steven K. MacLeod, Daniel J. Stein, James Donald Hayes, Donald L. Herber
  • METHOD FOR PREPARING SUSPENSIONS OF LOW-SOLUBILITY MATERIALS
    Publication number: 20150038439
    Abstract: A process for producing a pharmaceutical suspension that comprises an active pharmaceutical ingredient (“API”) having low solubility, the process comprises: (a) preparing a first solution comprising a carboxy-containing vinyl polymer and a solvent; and (b) adding a compound of the API to said first solution under conditions of high-shear mixing for a time from about 5 minutes to about 5 hours, said compound being soluble in said solvent, thereby producing a suspension of particles of said API in a composition comprising said carboxy-containing vinyl polymer; wherein a concentration of said API in said suspension is higher than a solubility of said API in said solvent. The present invention also provides a suspension produced by such process.
    Type: Application
    Filed: October 21, 2014
    Publication date: February 5, 2015
    Inventors: Steven K. MacLeod, Daniel J. Stein, James Donald Hayes, Donald L. Herber
  • Method for Preparing Suspensions of Low-Solubility Materials
    Publication number: 20100247666
    Abstract: A process for producing a pharmaceutical suspension that comprises an active pharmaceutical ingredient (“API”) having low solubility, the process comprises: (a) preparing a first solution comprising a carboxy-containing vinyl polymer and a solvent; and (b) adding a compound of the API to said first solution under conditions of high-shear mixing for a time from about 5 minutes to about 5 hours, said compound being soluble in said solvent, thereby producing a suspension of particles of said API in a composition comprising said carboxy-containing vinyl polymer; wherein a concentration of said API in said suspension is higher than a solubility of said API in said solvent. The present invention also provides a suspension produced by such process.
    Type: Application
    Filed: March 1, 2010
    Publication date: September 30, 2010
    Inventors: Steven K. MacLeod, Daniel J. Stein, James Donald Hayes, Donald L. Herber