Patents by Inventor Donald R. James
Donald R. James has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8791155Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondria) disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.Type: GrantFiled: September 26, 2011Date of Patent: July 29, 2014Assignee: Edison Pharmaceuticals, Inc.Inventors: Bing Wang, Gail Walkinshaw, Donald R. James
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Publication number: 20120178754Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.Type: ApplicationFiled: March 22, 2012Publication date: July 12, 2012Applicant: Compass Pharmaceuticals LLCInventors: Paul W. Baures, Donald R. James, Richard D. Gless, Thuy Tran, Herman J. Verheij, Jan C.C. Schultz
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Publication number: 20120088783Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondria) disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.Type: ApplicationFiled: September 26, 2011Publication date: April 12, 2012Applicant: Ampere Life Sciences, Inc.Inventors: Bing WANG, Gail Walkinshaw, Donald R. James
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Publication number: 20120071513Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.Type: ApplicationFiled: November 28, 2011Publication date: March 22, 2012Applicant: COMPASS PHARMACEUTICALS LLCInventors: David Kanne, John Ward, Gary Look, X. Michael Wang, Diva Chan, Tina Lee, Donald R. James, Richard Gless, John Schullek, Charles Vacin
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Publication number: 20110178087Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.Type: ApplicationFiled: March 30, 2011Publication date: July 21, 2011Applicant: Compass Pharmaceuticals LLC.Inventors: David Kanne, John Ward, Gary Look, X. Michael Wang, Diva Chan, Tina Lee, Donald R. James, Richard Gless, John Schullek, Charles Vacin
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Publication number: 20100222356Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.Type: ApplicationFiled: May 10, 2010Publication date: September 2, 2010Applicant: Compass Pharmaceuticals LLCInventors: Paul W. Baures, Donald R. James, Richard D. Gless, Thuy Tran, Herman J. Verheij, Jan C.C. Schultz
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Patent number: 7576094Abstract: The present invention is concerned with certain novel spiro substituted heterocylic ring derivatives. These compounds may be useful in the manufacture of pharmaceutical compositions for treating disorders mediated by lipoxygenases. They may also be useful in the manufacture of pharmaceutical formulations for the treatment of lipoxygenase-mediated disorders.Type: GrantFiled: December 9, 2005Date of Patent: August 18, 2009Assignee: Eli Lilly and CompanyInventors: Daniel T. W. Chu, Jian Chen, Wei Zhang, Xianfeng Li, Jiangao Song, Bing Wang, Qiang Cong, Donald R. James
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Publication number: 20090143411Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.Type: ApplicationFiled: October 18, 2005Publication date: June 4, 2009Applicant: COMPASS PHARMACEUTICALS LLCInventors: John Ward, Rama Jain, Donald R. James, Herman J. Verheij, Jan C.C. Schultz
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Publication number: 20090131445Abstract: The present invention provides novel compounds of the formula (I) and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.Type: ApplicationFiled: October 12, 2005Publication date: May 21, 2009Applicant: COMPASS PHARMACEUTICALS LLCInventors: Paul W. Baures, Donald R. James, Richard D. Gless, Thuy Tran, Jan C.C. Schultz
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Patent number: 7514461Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.Type: GrantFiled: September 15, 2004Date of Patent: April 7, 2009Assignee: Edison Pharmaceuticals, Inc.Inventors: Bing Wang, Gail Walkinshaw, Sekhar Boddupalli, Arkadij M. Elizarov, Xianming Jin, Xianfeng Li, Donald R. James, Jiangao Song, Jian Chen, Wei Zhang
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Publication number: 20090018145Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreating carcinomas) and mesotheliomas.Type: ApplicationFiled: October 18, 2005Publication date: January 15, 2009Applicant: Compass Pharmaceuticals LLCInventors: David Kanne, John Ward, Gary Look, X. Michael Wang, Diva Chan, Tina Lee, Donald R. James, Richard Gless, John Schullek, Charles Vacin
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Publication number: 20080207588Abstract: The present invention is concerned with certain novel derivatives of Formula I, wherein R, R1 to R10 are as described in the specification, and at least one CR5R6, or CR7R8, or CR9R10 is a an optionally substituted azetidine ring or an optionally substituted oxetan ring, which may be useful in the manufacture of pharmaceutical compositions for treating disorders mediated by lipoxygenases. They may also be useful in the manufacture of pharmaceutical formulations for the treatment of lipoxygenase mediated disorders.Type: ApplicationFiled: December 9, 2005Publication date: August 28, 2008Inventors: Daniel T. W. Chu, Donald R James, Bing Wang
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Patent number: 6109685Abstract: The present invention is a lounge chair that may be used by a person to comfortably lie on her back or stomach while supporting her arms and/or hands. In one embodiment, the lounge chair comprises a median member having a first end portion and a second end portion. The lounge chair further comprises a lower member and an upper member rotatably engaged with the first and second end portions of the median member, respectively. The lounge chair further comprises an arm support member rotatably engaged with the upper member. The arm support member comprises first and second arm portions disposed at opposite ends of the upper member.Type: GrantFiled: October 20, 1999Date of Patent: August 29, 2000Inventors: Donna L. Lindsey, Donald R. James
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Patent number: 6046136Abstract: This invention relates to novel optionally substituted heterocyclic N-oxide compounds of formula (I): ##STR1## wherein: R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, A, X, Z and m are defined herein. In other aspects, this invention relates to herbicidal compositions containing a optionally substituted heterocyclic N-oxide compound or derivative thereof and an agriculturally acceptable carrier and to a method of controlling undesirable vegetation by applying to an area where control is desired an herbicidally effective amount of an optionally substituted heterocyclic N-oxide compound or derivative thereof.Type: GrantFiled: June 24, 1997Date of Patent: April 4, 2000Assignee: Zeneca LimitedInventors: Donald R. James, Christopher J. Mathews
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Patent number: 5928998Abstract: Substituted arylindazoles of the formula: ##STR1## wherein X is CR.sup.14 and R.sup.14 is hydrogen, halogen, haloalkyl, cyano, nitro, alkylthio, alkylsulfonyl, alkylsulfinyl or alkoxy; and substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and R.sup.8 are as defined in the specification. Use of the compounds as herbicides and methods of making the compounds are also described.Type: GrantFiled: December 9, 1996Date of Patent: July 27, 1999Assignee: Zeneca LimitedInventors: Donald R. James, Don R. Baker, Steven D. Mielich, William J. Michaely, Steven Fitzjohn, Christopher G. Knudsen, Christopher Mathews, John M. Gerdes
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Patent number: 5858166Abstract: The present invention is a machine for use in attaching first and second handles to a gift box. Each of the first and second handles having first and second end portions and an upper portion. In one embodiment, the machine comprises a base member and first and second side walls extending upward therefrom. The machine further comprises first and second handle support members rotatably connected with the first and second side walls and each being adapted to retain the first and second handles, respectively. The first and second handle support members are operable from a first and normally horizontal position wherein the handles may be inserted thereon and provided with an adhesive to a second substantially vertical position wherein the handles may be attached to the gift box.Type: GrantFiled: October 28, 1996Date of Patent: January 12, 1999Inventors: Donald R. James, Bill Anderson
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Patent number: 5786301Abstract: This invention relates to substituted N-benzotriazoles of the formula ##STR1## in which: R.sup.1, R.sup.2, R.sup.3,R.sup.4, R.sup.5,R.sup.6, R.sup.7, X are as defined in the specification. The compounds exhibit herbicidal activity.Type: GrantFiled: August 8, 1996Date of Patent: July 28, 1998Assignee: Zeneca LimitedInventors: Donald R. James, Raymond A. Felix
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Patent number: 5560183Abstract: A collator and stacking apparatus, system and method for the collation and stacking of asymmetric plastic blister packages having a blister at or toward one end on a flat card, which comprises package-receiving inverter and sliding trays each with a tray surface, upwardly extending sides and a one and other end, for receiving each a package thereon, the received package being in the same orientation on each tray surface. The inverter trays have stops to position the received package on the tray surface as it moves between a package receiving position and an inverted package discharge position, wherein the package is inverted and placed within a collation track perpendicular to the trays, the track having a first and second end for receiving periodically an inverted package from the inverter tray and a slidable package from the sliding tray in a spaced-apart alternating arrangement within the track rails.Type: GrantFiled: November 1, 1994Date of Patent: October 1, 1996Assignee: Sencorp Systems, Inc.Inventor: Donald R. James
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Patent number: 5444038Abstract: This invention relates to substituted aryl indazoles, a process for producing them and their use as herbicides. In particular this invention relates to substituted aryl indazoles of the formula ##STR1## wherein all variables are as defined in the specification.Type: GrantFiled: March 2, 1993Date of Patent: August 22, 1995Assignee: Zeneca LimitedInventors: Donald R. James, Don R. Baker, Steven D. Mielich, William J. Michaely, Steven Fitzjohn, Christopher G. Knudsen, Christopher Mathews, John M. Gerdes
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Patent number: 5369086Abstract: Substituted N-benzotriazoles of the general formula ##STR1## exhibit herbicidal activity. Herbicidal compositions and related methods of using the substituted N-benzotriazoles are also disclosed.Type: GrantFiled: April 28, 1993Date of Patent: November 29, 1994Assignee: Zeneca LimitedInventors: Donald R. James, Raymond A. Felix