Patents by Inventor Dorit Landstein

Dorit Landstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMANIZED ANTIBODIES SPECIFIC FOR HSP65-DERIVED PEPTIDE-6, METHODS AND USES THEREOF
    Publication number: 20170218056
    Abstract: The present invention relates to humanized antibodies that specifically bind a polypeptide comprising peptide-6 as denoted by SEQ ID NO. 15, that is an HSP65 derived peptide. More specifically, the invention relates to humanized anti-peptide-6 antibodies, compositions, methods and uses thereof for the treatment of immune-related disorders, specifically, inflammatory disorders such as arthritis, IBD, psoriasis, diabetes and MS. The invention further provides combined compositions and kit combining the humanized antibodies of the invention and at least one anti-inflammatory agent, as well as uses of the humanized antibodies in diagnostic kits and methods.
    Type: Application
    Filed: April 19, 2017
    Publication date: August 3, 2017
    Inventors: Yaakov Naparstek, Shira Yair, Dorit LANDSTEIN
  • HUMANIZED ANTIBODIES SPECIFIC FOR HSP65-DERIVED PEPTIDE-6, METHODS AND USES THEREOF
    Publication number: 20140170138
    Abstract: The present invention relates to humanized antibodies that specifically bind a polypeptide comprising peptide-6 as denoted by SEQ ID NO. 15, that is an HSP65 derived peptide. More specifically, the invention relates to humanized anti-peptide-6 antibodies, compositions, methods and uses thereof for the treatment of immune-related disorders, specifically, inflammatory disorders such as arthritis, IBD, psoriasis, diabetes and MS. The invention further provides combined compositions and kit combining the humanized antibodies of the invention and at least one anti-inflammatory agent, as well as uses of the humanized antibodies in diagnostic kits and methods.
    Type: Application
    Filed: January 31, 2014
    Publication date: June 19, 2014
    Applicant: Protab Ltd.
    Inventors: Yaakov Naparstek, Shira Yair, Dorit LANDSTEIN
  • METHOD AND ASSAY FOR GLYCOSYLATION PATTERN DETECTION RELATED TO CELL STATE OF STEM CELLS
    Publication number: 20130315881
    Abstract: A method and assay for characterizing populations of stem cells according to their glycosylation pattern, particularly for distinguishing between stem cell populations, for example with regard to state of differentiation.
    Type: Application
    Filed: April 23, 2013
    Publication date: November 28, 2013
    Applicants: YEDA RESEARCH AND DEVELOPMENT CO. LTD., Procognia (Israel) Ltd.
    Inventors: Dov ZIPORI, Vered MORAD, Rakefet ROSENFELD, Albena SAMOKOVLISKY, Yeshayahu YAKIR, Dorit LANDSTEIN, Noa ZALLE, Ronny ALONI
  • Method and Assay for Glycosylation Pattern Detection Related to Cell State
    Publication number: 20120165206
    Abstract: A method and assay for characterizing populations of cells according to their glycosylation pattern, particularly for distinguishing between cell populations. In preferred embodiments the present invention is able to determine the state of a stem cell (ie differentiated or undifferentiated) and/or the state of a cancer cell, for example with regard to malignancy. Preferably the present invention is also able to determine whether a patient is likely to respond to a drug according to the glycosylation pattern of a sample of cancer cells taken from the patient (or alternatively examined while in the patient, as described in greater detail below). Also optionally, it may be used to analyze a cell population before and after treatment with a drug for example.
    Type: Application
    Filed: July 11, 2007
    Publication date: June 28, 2012
    Inventors: Rakefet Rosenfeld, Noa Zalle, Dorit Landstein, Albena Samokovlisky, Ronny Aloni, Ruth Maya, Yeshayahu Yakir
  • DIAGNOSIS OF CANCERS THROUGH GLYCOME ANALYSIS
    Publication number: 20120165221
    Abstract: Markers and methods of diagnosis and monitoring of cancer through global glycome analysis.
    Type: Application
    Filed: September 7, 2010
    Publication date: June 28, 2012
    Inventors: Dorit Landstein, Allbena Samokovlisky, Boris Gorelik, Ilana Belzer, Mor Goldenberg-, Oshry Biton, Rakefet Rosenfeld, Shoshy Mizrahy, Yeshayahu Yakir