Patents by Inventor Doron Steinberg

Doron Steinberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220087275
    Abstract: Compositions comprising magnesium enriched liquids re provided. Specifically, compositions comprising magnesium enriched milk and/or milk product, wherein a concentration of magnesium ions in said milk and/or milk product ranges from 8 mM to 25 mM, and methods of producing the same, are provided.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 24, 2022
    Inventors: Moshe SHEMESH, Doron STEINBERG, Ram REIFEN
  • Publication number: 20210379010
    Abstract: The invention provides compositions comprising at least one cannabinoid compound, for use in the method of treating and preventing a disease, condition or symptom caused by, or associated with fungi, bacteria and microbes.
    Type: Application
    Filed: October 30, 2019
    Publication date: December 9, 2021
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Doron STEINBERG, Raphael MECHOULAM
  • Publication number: 20210000890
    Abstract: A composition comprising at least one sugar alcohol and a population of viable probiotic bacteria belonging to the class Bacilli is disclosed. The product is devoid of sugar or comprises no more than 5% of the amount of said sugar alcohol in the composition, the composition being formulated for oral delivery.
    Type: Application
    Filed: July 2, 2020
    Publication date: January 7, 2021
    Applicants: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization, Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Moshe SHEMESH, Doron STEINBERG
  • Patent number: 10843013
    Abstract: The present invention discloses liquid precursor compositions adapted for application on a hard surface in the oral cavity, comprising at least one therapeutic agent suitable for the treatment of oral disorders, at least one acidic-pH sensitive polymer, at least one hydrophobic polymer, and a pharmaceutically acceptable volatile carrier, wherein a weight ratio between said at least one hydrophobic polymer and said at least one acidic-pH sensitive polymer is larger than 1. The invention also discloses formulations formed of the solidification of these compositions, and methods for treating oral disorders by applying these compositions on hard surfaces in the oral cavity or to be placed in the oral cavity.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: November 24, 2020
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEWBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Michael Friedman, Doron Steinberg, Irith Gati
  • Patent number: 10485792
    Abstract: The present invention discloses a method of treating a head and neck cancer or preventing the development of pre-malignant lesions to this cancer, by administering locally to the oral cavity, a sustained release drug delivery system comprising a drug for the treatment of this cancer or for the prevention of said lesions, and at least one polymer, such that said system is attached to a surface in the oral cavity and remains attached thereto for at least 1 hour, accompanied by release of the drug and maintaining an effective therapeutic concentration thereof in the cavity, for at least 1 hour. Further are disclosed a sustained release drug delivery system and a liquid precursor varnish composition to this system.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: November 26, 2019
    Assignees: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Michael Friedman, Rakefet Czernimski, Silvio Gutkind, Doron Steinberg, Irith Gati, Zakhar Nudelman
  • Publication number: 20190298649
    Abstract: Provided herein injectable implant compositions useful for acceleration of bone fracture healing, treatment of dental or oral pathologies, and controlled drug delivery.
    Type: Application
    Filed: September 19, 2017
    Publication date: October 3, 2019
    Inventors: Michael FRIEDMAN, David KIRMAYER, Rami MOSHEIFF, Jacob RACHMILEWITZ, Amal KHOURY, Doron STEINBERG
  • Publication number: 20190289866
    Abstract: Compositions comprising magnesium enriched liquids re provided. Specifically, compositions comprising magnesium enriched milk and/or milk product, wherein a concentration of magnesium ions in said milk and/or milk product ranges from 8 mM to 25 mM, and methods of producing the same, are provided.
    Type: Application
    Filed: September 8, 2016
    Publication date: September 26, 2019
    Inventors: Moshe SHEMESH, Doron STEINBERG, Ram REIFEN
  • Publication number: 20190099523
    Abstract: The present invention discloses a liquid precursor composition adapted for application on a on a desired surface, this composition comprising: a. at least one therapeutic agent suitable for the treatment or prevention of a disorder or pathological condition, wherein said disorder or pathological condition excludes oral disorders, b. at least one acidic-pH sensitive polymer, c. at least one hydrophobic polymer, and d. a pharmaceutically acceptable volatile solvent, wherein a weight ratio between the at least one hydrophobic polymer and the at least one acidic-pH sensitive polymer is larger than 1.
    Type: Application
    Filed: October 9, 2018
    Publication date: April 4, 2019
    Inventors: Michael Friedman, Doron Steinberg, Eran Lavy
  • Publication number: 20140328895
    Abstract: The present invention discloses a liquid precursor composition adapted for application on a on a desired surface, this composition comprising: a. at least one therapeutic agent suitable for the treatment or prevention of a disorder or pathological condition, wherein said disorder or pathological condition excludes oral disorders, b. at least one acidic-pH sensitive polymer, c. at least one hydrophobic polymer, and d. a pharmaceutically acceptable volatile solvent, wherein a weight ratio between the at least one hydrophobic polymer and the at least one acidic-pH sensitive polymer is larger than 1.
    Type: Application
    Filed: March 25, 2012
    Publication date: November 6, 2014
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd.
    Inventors: Michael Friedman, Doron Steinberg, Eran Lavy
  • Patent number: 8865909
    Abstract: Novel agents exhibiting anti-biofilm formation activity while being non-cytotoxic are provided, as well as methods of using the same, either per se or conjugated to a polymer, for preventing and/or reducing the formation of microbial biofilms and/or for disrupting microbial biofilms. The novel agents described herein include thiazolidine-2,4-diones (TZDs), pyrrolidine-2,5-diones (PYDs), imidazolidine-2,4-diones or oxazolidine-2,4-diones, substituted by an alkyl having 7-20 carbon atoms in its backbone chain.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: October 21, 2014
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hadasit Medical Research Services and Development Ltd.
    Inventors: Morris Srebnik, Itzhack Polacheck, Doron Steinberg, Adel Jabbour, Edward Sionov
  • Publication number: 20130018069
    Abstract: The present invention discloses a method of treating a head and neck cancer or preventing the development of pre-malignant lesions to this cancer, by administering locally to the oral cavity, a sustained release drug delivery system comprising a drug for the treatment of this cancer or for the prevention of said lesions, and at least one polymer, such that said system is attached to a surface in the oral cavity and remains attached thereto for at least 1 hour, accompanied by release of the drug and maintaining an effective therapeutic concentration thereof in the cavity, for at least 1 hour. Further are disclosed a sustained release drug delivery system and a liquid precursor varnish composition to this system.
    Type: Application
    Filed: August 25, 2010
    Publication date: January 17, 2013
    Applicant: YISSUM Research Development Company of the Hebrew University of Jerusalem, LTD
    Inventors: Michael Friedman, Rakefet Czernimski, Silvio Gutkind, Doron Steinberg, Irith Gati, Zakhar Nudelman
  • Publication number: 20120288566
    Abstract: The present invention discloses liquid precursor compositions adapted for application on a hard surface in the oral cavity, comprising at least one therapeutic agent suitable for the treatment of oral disorders, at least one acidic-pH sensitive polymer, at least one hydrophobic polymer, and a pharmaceutically acceptable volatile carrier, wherein a weight ratio between said at least one hydrophobic polymer and said at least one acidic-pH sensitive polymer is larger than 1. The invention also discloses formulations formed of the solidification of these compositions, and methods for treating oral disorders by applying these compositions on hard surfaces in the oral cavity or to be placed in the oral cavity.
    Type: Application
    Filed: October 5, 2010
    Publication date: November 15, 2012
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Michael Friedman, Doron Steinberg, Irith Gati
  • Publication number: 20110281921
    Abstract: Novel agents exhibiting anti-biofilm formation activity while being non-cytotoxic are provided, as well as methods of using the same, either per se or conjugated to a polymer, for preventing and/or reducing the formation of microbial biofilms and/or for disrupting microbial biofilms. The novel agents described herein include thiazolidine-2,4-diones (TZDs), pyrrolidine-2,5-diones (PYDs), imidazolidine-2,4-diones or oxazolidine-2,4-diones, substituted by an alkyl having 7-20 carbon atoms in its backbone chain.
    Type: Application
    Filed: November 19, 2009
    Publication date: November 17, 2011
    Applicants: Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Morris Srebnik, Itzhack Polacheck, Doron Steinberg, Adel Jabbour, Edward Sionov
  • Publication number: 20100195781
    Abstract: A liquid lithium jet nozzle comprising: an inlet through which liquid lithium flows into the nozzle; an inlet flow channel that receives liquid lithium that flows into the nozzle via the inlet and shapes the flowing liquid lithium to flow in a thin film; and a flow region that receives flowing liquid lithium shaped by the flow channel and in which the liquid lithium flows with at least one large surface of the film exposed.
    Type: Application
    Filed: July 10, 2008
    Publication date: August 5, 2010
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Soreq Nuclear Research Center, Hadasit Medical Research Services & Development Ltd.
    Inventors: Michael Paul, Morris Srebnik, Alex Arenshtam, Shlomi Halfon, Dany Kijel, Itzhak Polacheck, Avraham Rubinstein, Doron Steinberg
  • Publication number: 20090074910
    Abstract: Disclosed are chewing gums that are organoleptically acceptable, and have high adherence to plaque bacteria. A chewing gum according to an exemplary embodiment contains a gum base, at least one edible acid, and optionally other ingredients. The invention also provides a method for preparing a chewing gum composition, which includes triturating of coloring agent, and a method for commercially producing and marketing chewing gums, which includes testing the chewing gums for adhesion to bacteria, such as plaque bacteria.
    Type: Application
    Filed: February 22, 2006
    Publication date: March 19, 2009
    Applicants: Strauss Group Ltd., Yissum Research Development Company of the Hebrew University of Je
    Inventors: Doron Steinberg, Shlomo Magdassi, Alexander Kamyshny, Haim Zegerman, Arie Letzter
  • Publication number: 20070155698
    Abstract: The invention relates to a composition for modulation of at least one bacteria-related parameter comprising oxazaborolidine derivative compounds. The invention additionally relates to new oxazaborolidine derivative compounds. The invention further relates to a composition for decreasing bacterial growth, a composition for increasing the susceptibility of bacteria to the cytotoxic effects of other antibacterial agents, and a pharmaceutical composition comprising as an active ingredient an oxazaborolidine derivative compound. Methods for modulating at least one bacteria-related parameter, for preventing, decreasing or eliminating bacterial growth, and for making bacteria more susceptible to other antibacterial compounds are also described.
    Type: Application
    Filed: September 2, 2004
    Publication date: July 5, 2007
    Inventors: Doron Steinberg, Morris Srebnik, Adel Jabbour, Arik Moussaieff, Valery Dembitsky, Moshe Bronshteyn
  • Publication number: 20050058744
    Abstract: An edible and/or chewable article of manufacture containing at least one food grade substance having adsorption affinity towards at least one dental plaque (biofilm) constituent and capable of reducing and/or removing the oral biofilm while present in the mouth. Particular articles of manufacture are chewing gums, sweets, candies, candy, and other nutritional bars, ice creams, chocolates, confectionery and bakery/pastry products, honey, dairy products and beverages, and oral hygiene products such as tooth pastes, oral gels and mouthwashes. A chewing gum having a conventional gum base and at least one food grade active substance having adsorption affinity towards at least one dental plaque (biofilm) constituent (bacteria and proteins and bacterial cell-free enzymes) and capable of reducing and/or removing the oral biofilm while present in the mouth.
    Type: Application
    Filed: July 1, 2004
    Publication date: March 17, 2005
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
    Inventors: Doron Steinberg, Alexander Kamyshny, Shlomo Magdassi
  • Patent number: 5023082
    Abstract: The present invention pertains to biodegradable sustained-release composins capable of achieving the sustained release of a pharmaceutical or other agent. The compositions can be formed into implant devices which may be used to treat a wide variety of diseases and conditions. The implants are especially useful in treating diseases such as periodontal disease which require prolonged drug release.
    Type: Grant
    Filed: March 30, 1988
    Date of Patent: June 11, 1991
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Michael Friedman, Doron Steinberg, Aubrey Soskolne