Abstract: The present invention is directed to the anti-LAG-3 antibodies, LAG-3 mAb 1, LAG-3 mAb 2, LAG-3 mAb 4, LAG-3 mAb 5, and LAG-3 mAb 6, and to humanized and chimeric versions of such antibodies. The invention additionally pertains to LAG-3-binding molecules that comprise LAG-3 binding fragments of such anti-LAG-3 antibodies, immunocongugates, and to bispecific molecules, including diabodies, BiTEs, bispecific antibodies, etc., that comprise (i) such LAG-3-binding fragments, and (ii) a domain capable of binding an epitope of a molecule involved in regulating an immune check point present on the surface of an immune cells. The present invention also pertains to methods of detecting LAG-3, as well as methods of using molecules that bind LAG-3 for stimulating immune responses.

Abstract: A compact food container organizer by which variously sized food containers and their lids are stored and sorted in a neat and orderly manner. The organizer has a plurality of upstanding pedestals attached to a flat support base. At least some of the pedestals have respective disk-shaped end caps detachably connected to and removable from the tops thereof. The lengths of the upstanding pedestals above the support base and the diameters of the disk-shaped end caps vary so that stacks of different food containers can first be inverted and then positioned over correspondingly sized pedestals so that the bottoms of the containers are seated on opposing end caps connected to the pedestals. A plurality of lid baskets having different sizes are attached to the support base to accommodate therewithin lids of different sizes that cover the food containers.

Abstract: A compact food container organizer by which variously sized food containers and their lids are stored and sorted in a neat and orderly manner. The organizer has a plurality of upstanding pedestals attached to a flat support base. At least some of the pedestals have respective disk-shaped end caps detachably connected to and removable from the tops thereof. The lengths of the upstanding pedestals above the support base and the diameters of the disk-shaped end caps vary so that stacks of different food containers can first be inverted and then positioned over correspondingly sized pedestals so that the bottoms of the containers are seated on opposing end caps connected to the pedestals. A plurality of lid baskets having different sizes are attached to the support base to accommodate therewithin lids of different sizes that cover the food containers.

Abstract: A compact food container organizer by which variously sized food containers and their variously sized lids are stored and sorted in a neat and orderly manner. The organizer has stacks of pedestals lying side-by-side one another and attached to a flat support base. Each stack has one or more preferably disk-shaped pedestals lying one above the other over the base. The diameters of the successive ones of disk-shaped pedestals vary so that different food containers having different sizes can first be inverted and then positioned over the top of and around the correspondingly sized pedestals. A plurality of lid baskets having different sizes are attached to the support base to accommodate therewithin the variously sized lids that cover the food containers.

Abstract: A compact support for a battery charger and a cable to be connected from the battery charger to a cell phone or other battery-powered device. The support includes a base on which the battery charger is seated and a stand having a winding hub projecting therefrom. Slots are formed through the base to receive respective terminals (i.e., prongs) of the battery charger to attach the battery charger to the support. The winding hub projecting from the stand has a pair of hub arms and respective tongues which turn away from the arms and each other. The cable of the battery charger is first wrapped around the pair of hub arms so as to lie between the tongues thereof and the stand and then removably retained by one or more notches formed in the stand and one of the tongues of the hub arms.

Abstract: A compact support for a battery charger and a cable to be connected from the battery charger to a cell phone or other battery-powered device. The support includes a base on which the battery charger is seated and a stand having a winding hub projecting therefrom. Slots are formed through the base to receive respective terminals (i.e., prongs) of the battery charger to attach the battery charger to the support. The winding hub projecting from the stand has a pair of hub arms and respective tongues which turn away from the arms and each other. The cable of the battery charger is first wrapped around the pair of hub arms so as to lie between the tongues thereof and the stand and then removably retained by one or more notches formed in the stand and one of the tongues of the hub arms.

Abstract: The present invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity.

Abstract: The present invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity.

Abstract: This invention relates to compounds of the formula 1 wherein G, D, A, Z, Q, X, Y, R1, and R4 through R7 are defined as in the specification, processes for preparing the same and intermediates used in making the same, and pharmaceutical compositions containing such compounds and their use in the treatment of central nervous system disorders and other disorders.

Abstract: The present invention provides novel 5-substituted tetralones of Formulas I, II, III, and IV and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, which are useful for treating and preventing uncontrolled or abnormal proliferation of tissues, such as cancer, atherosclerosis, restenosis, and psoriasis.

Abstract: The present invention provides novel 5-substituted tetralones of Formulas (I), (II), (III) and (IV) and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, which are useful for treating and preventing uncontrolled or abnormal proliferation of tissues, such as cancer, atherosclerosis, restenosis, and psoriasis. Specifically, the present invention relates to compounds that inhibit the farnesyl transferase enzyme.

Abstract: Disclosed are a die carrier and associated method for conducting probe beam tests on chips designed to be packaged in flip-chip packages. The die carrier is a specially modified membrane type carrier that includes a probe access region, such as an opening, in the membrane. A die to be tested is mounted in the die carrier such that its I/O pads make electrical contact with corresponding bump contacts on the membrane. The die/carrier assembly is then mounted in a test socket provided on a chip testing apparatus such that electrical I/O signals can be provided to and from an external test circuit. While the die is being electrical tested, a probe beam is directed through the probe access region and onto the chip active surface. In this manner, the chip active surface is probed while exposed to electrical stimulus.

Abstract: Disclosed are a die carrier and associated method for conducting probe beam tests on chips designed to be packaged in flip-chip packages. The die carrier is a specially modified membrane type carrier that includes a probe access region, such as an opening, in the membrane. A die to be tested is mounted in the die carrier such that its I/O pads make electrical contact with corresponding bump contacts on the membrane. The die/carrier assembly is then mounted in a test socket provided on a chip testing apparatus such that electrical I/O signals can be provided to and from an external test circuit. While the die is being electrical tested, a probe beam is directed through the probe access region and onto the chip active surface. In this manner, the chip active surface is probed while exposed to electrical stimulus.

Abstract: A method and an apparatus are disclosed for positioning an integrated circuit chip to be tested on a device-under-test ("DUT") interface board without using a hold-down plate and for attaching this interface board to a feed-through interface module so that the device being tested makes abutting contact with the feed-through interface module and so that the contact pins of the device being tested make abutting electrical contact with contact pin sockets on the DUT interface board. This arrangement provides a path for heat and ion dissipation from the chip being tested in a simple and elegant manner which also minimizes potential damage to the chip.