Patents by Inventor Dramane Ibrahim Laine

Dramane Ibrahim Laine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazopyridine derivatives
    Patent number: 9394304
    Abstract: The invention is concerned with a compound of formula (I) wherein R1, R2, R2?, R3, R3? are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: July 19, 2016
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Stephan Bachmann, Shawn David Erickson, Dramane Ibrahim Laine, Yimin Qian
  • MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS
    Publication number: 20160002220
    Abstract: Methods of using Muscarinic Acetylcholine Receptor Antagonists are provided.
    Type: Application
    Filed: September 10, 2015
    Publication date: January 7, 2016
    Inventors: Dramane Ibrahim Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • INHIBITORS OF BRUTON'S TYROSINE KINASE
    Publication number: 20150290192
    Abstract: This application discloses the Btk inhibitor compounds 6-tert-Butyl-8-fluoro-2-{3-hydroxymethyl-4-[1-methyl-5-(1?-methyl-1?,2?,3?,4?,5?,6?-hexahydro-[3,4?]bipyridinyl-6-ylamino)-6-oxo-1,6-dihydro-pyridazin-3-yl]-pyridin-2-yl}-2H-phthalazin-1-one, 2-(2-{3-[5-(5-Azetidin-1-ylmethyl-1-methyl-1H-pyrazol-3-ylamino)-1-methyl-6-oxo-1,6-dihydro-pyridazin-3-yl]-2-hydroxy methyl-phenyl}-8-fluoro-1-oxo-1,2-dihydro-isoquinolin-6-yl)-2-methyl-propionitrile, and 6-tert-Butyl-2-[2-hydroxymethyl-3-(5-{5-[(2-methoxy-ethylamino)-methyl]-pyridin-2-ylamino}-6-oxo-1,6-dihydro-pyridin-3-yl)-phenyl]-3,4-dihydro-2H-isoquinolin-1-one, formulations thereof, and methods of treatment of asthma, as described herein.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 15, 2015
    Inventors: Raman Mahadevan Iyer, Dramane Ibrahim Laine, Francisco Javier Lopez-Tapia, Jonathan E. Phillips, Christopher Stevenson
  • Muscarinic acetylcholine receptor antagonists
    Patent number: 9144571
    Abstract: Methods of using Muscarinic Acetylcholine Receptor Antagonists are provided.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: September 29, 2015
    Assignee: Glaxo Group Limited
    Inventors: Dramane Ibrahim Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • IMIDAZOPYRIDINE DERIVATIVES
    Publication number: 20150246918
    Abstract: The invention is concerned with a compound of formula (I) wherein R1, R2, R2?, R3, R3? are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: May 14, 2015
    Publication date: September 3, 2015
    Applicant: Hoffmann-La Roche Inc.
    Inventors: STEPHAN BACKMANN, SHAWN DAVID ERICKSON, DRAMANE IBRAHIM LAINE, YIMIN QIAN
  • MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS
    Publication number: 20150238470
    Abstract: Methods of using Muscarinic Acetylcholine Receptor Antagonists are provided.
    Type: Application
    Filed: May 8, 2015
    Publication date: August 27, 2015
    Inventors: Dramane Ibrahim Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • Muscarinic acetylcholine receptor antagonists
    Patent number: 9045469
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: June 2, 2015
    Assignee: Glaxo Group Limited
    Inventors: Dramane Ibrahim Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS
    Publication number: 20140371264
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Application
    Filed: September 4, 2014
    Publication date: December 18, 2014
    Inventors: Dramane Ibrahim Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • Muscarinic acetylcholine receptor antagonists
    Patent number: 8853404
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: October 7, 2014
    Assignee: Glaxo Group Limited
    Inventors: Dramane Ibrahim Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS
    Publication number: 20140080863
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Application
    Filed: October 14, 2013
    Publication date: March 20, 2014
    Applicant: Glaxo Group Limited
    Inventors: Dramane Ibrahim LAINE, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • Muscarinic acetylcholine receptor antagonists
    Patent number: 8575347
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: November 5, 2013
    Assignee: Glaxo Group Limited
    Inventors: Dramane Ibrahim Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • Novel Combination of Therapeutic Agents
    Publication number: 20100329996
    Abstract: Novel combinations of a muscarinic acetylcholine receptor antagonist and a beta 2 agonist and/or a corticosteroid for inhaled administration via the nose or mouth, and methods of using them are provided herein.
    Type: Application
    Filed: September 12, 2008
    Publication date: December 30, 2010
    Inventor: Dramane Ibrahim Laine
  • Cathepsin C Inhibitors
    Publication number: 20090264498
    Abstract: This invention relates to compounds of formula (I) which are useful for treating chronic obstructive pulmonary disease, and the like.
    Type: Application
    Filed: April 16, 2009
    Publication date: October 22, 2009
    Inventors: Dramane Ibrahim Laine, Guoliang Lin, Brent W. McCleland, Michael R. Palovich
  • Cathepsin C Inhibitors
    Publication number: 20090264499
    Abstract: A compound of formula (IA) or (IB) and their use in treating inflammatory diseases such as COPD.
    Type: Application
    Filed: April 16, 2009
    Publication date: October 22, 2009
    Inventors: Jianghe DENG, Dramane Ibrahim Laine, Brent W. McCleland, Michael R. Palovich, Emilie Veronique Petitjean
  • NOVEL CATHEPSIN C INHIBITORS AND THEIR USE
    Publication number: 20090264431
    Abstract: The invention is directed to compounds according to Formula I: wherein R1, R2a, R2b, R2c, R3, and n are defined below, and to pharmaceutically-acceptable salts thereof. They are cathepsin C inhibitors and can be used in the treatment of diseases mediated by the cathepsin C enzyme, such as COPD.
    Type: Application
    Filed: August 18, 2008
    Publication date: October 22, 2009
    Inventors: Michael R. Palovich, Haibo Xie, Jianghe Deng, Dramane Ibrahim Laine
  • MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS
    Publication number: 20090076061
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Application
    Filed: August 5, 2005
    Publication date: March 19, 2009
    Inventors: Jakob Busch-Petersen, Michael R. Palovich, Dramane Ibrahim Laine
  • M3 Muscarinic Acetylcholine Receptor Antagonists
    Publication number: 20080275079
    Abstract: Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.
    Type: Application
    Filed: August 2, 2006
    Publication date: November 6, 2008
    Inventors: Jakob Busch-Petersen, Dramane Ibrahim Laine, Michael R. Palovich, Roderick S. Davis, Wei Fu, Haibo Xie
  • 5-Acylamino-1,1?-biphenyl-4-carboxamide derivatives and their use as P38 kinase inhibitors
    Patent number: 7432289
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: October 7, 2008
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Suzanne Joy Merrick, Kathryn Jane Smith, Ann Louise Walker
  • M3 Muscarinic Acetylcholine Receptor Antagonists
    Publication number: 20080234315
    Abstract: The present invention is directed to novel Muscarinic Acetylcholine receptor antagonists of Formula (I), pharmaceutical compositions and methods of using them. Compounds of Formula (I) are, inter alia, wherein: R1 and R2 are, independently, selected from the group consisting of 3-thienyl, pyridyl, benzyl, pyrimidyl, thiazolyl, isothiazolyl and C3-7cycloalkyl.
    Type: Application
    Filed: August 2, 2006
    Publication date: September 25, 2008
    Inventors: Jakob Busch-Petersen, Dramane Ibrahim Laine, Michael R. Palovich, Roderick S. Davis, Wei Fu, Haibo Xie
  • Biphenylcarboxylic amide derivatives as p38 kinase inhibitors
    Patent number: 7309800
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: December 18, 2007
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker