Patents by Inventor Durga Prasad Konakanchi

Durga Prasad Konakanchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11465988
    Abstract: The present invention provides a process for the preparation of Tipiracil HCl of Formula (I) and intermediate thereof with improved yields and purities.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: October 11, 2022
    Assignee: NATCO PHARMA LIMITED
    Inventors: Srinivasulu Sakkani, Uma Naresh Babu Kotra, Dharmender Ragidi, Buchappa Gongalla, Durga Prasad Konakanchi, Pulla Reddy Muddasani, Venkaiah Chowdary Nannapaneni
  • Publication number: 20220259204
    Abstract: The present invention relates to a process for the preparation of 4-(4-{[2-(4-chlorophenyl)-4,4dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2,3-b] pyridin-5-yloxy)benzamide) compound of formula-1 which is represented by the following structural formula:
    Type: Application
    Filed: July 8, 2020
    Publication date: August 18, 2022
    Inventors: Balakrishna Reddy SIRIGIREDDY, Veeraswamy BALINA, Sreenivas RACHAKONDA, Veerender MURKI, Durga Prasad KONAKANCHI, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI
  • Patent number: 11414421
    Abstract: The present invention relates to an improved process for the preparation of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate (1/1) compound of formula-1a and its novel crystalline forms.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: August 16, 2022
    Assignee: NATCO PHARMA LTD
    Inventors: Arunkumar Thiriveedhi, Swapna Kondaveeti, Sathish Thumati, Naresh Ghanta, Janaki Rama Rao Ravi, Durga Prasad Konakanchi, Pulla Reddy Muddansani, Venkaiah Chowdary Nannapaneni
  • Publication number: 20220089607
    Abstract: The present invention relates to a process for the preparation of high pure Eribulin and Eribulin Mesylate. The present invention involves preparation of high pure Eribulin and its mesylate salt involving chiral acid addition salts of Eribulin.
    Type: Application
    Filed: November 27, 2019
    Publication date: March 24, 2022
    Inventors: Prabhakar DIVYA, Srinivasu KASA, Durga Prasad KONAKANCHI, Ramesh DANDALA, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI
  • Publication number: 20220056016
    Abstract: The present invention provides a process for the preparation of Tipiracil HCl of Formula (I) and intermediate thereof with improved yields and purities.
    Type: Application
    Filed: December 13, 2019
    Publication date: February 24, 2022
    Applicant: NATCO PHARMA LIMITED
    Inventors: Srinivasulu SAKKANI, Uma Naresh Babu KOTRA, Dharmender RAGIDI, Buchappa GONGALLA, Durga Prasad KONAKANCHI, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI
  • Patent number: 11111228
    Abstract: The present invention is related to an improved process for the preparation of Pomalidomide with higher yields and high purity. Particularly the present invention relates to form A preparation of Pomalidomide and its purification. wherein the present process doesn't involve use of dioxane solvent and avoids higher temperatures.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: September 7, 2021
    Assignee: Natco Pharma Limited
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Dharmendher Ragidi, Uma Naresh Babu Kotra, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Patent number: 11008296
    Abstract: The present invention relates to novel intermediates of Eribulin and process for the preparation of the same. The process of the present invention is commercially viable and can be easily adopted for plant scale operations. The present invention relates to tetrahydrofuran compounds of formula I, X, XI, D and B.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: May 18, 2021
    Assignee: Natco Pharma Limited
    Inventors: Bulli Babi Vipparla, Sreenivas Nagapuri, Sathaiah Kandula, Janaki Rama Rao Ravi, Durga Prasad Konakanchi, Pulla Reddy Muddasani, Venkaiah Chowdary Nannapaneni
  • Publication number: 20210122754
    Abstract: The present invention relates to an improved process for the preparation of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate (1/1) compound of formula-1a and its novel crystalline forms.
    Type: Application
    Filed: January 10, 2019
    Publication date: April 29, 2021
    Inventors: Arunkumar THIRIVEEDHI, Swapna KONDAVEETI, Sathish THUMATI, Naresh GHANTA, Janaki Rama Rao RAVI, Durga Prasad KONAKANCHI, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI
  • Patent number: 10870650
    Abstract: The present invention relates to a process for the preparation of stable and 5 pure amorphous form of Idelalisib. Further, the present process is simple, more economical, cost effective and efficient method of manufacturing that is suitable for industrial scale-up having a high degree of chromatographic purity.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: December 22, 2020
    Assignee: NATCO PHARMA LIMITED
    Inventors: Amala Kompella, Sreenivas Rachakonda, Venugopala Krishna Gampa, Subhash Kusumba, Durga Prasad Konakanchi, Pulla Reddy Muddasani, Venkaiah Chowdary Nannapaneni
  • Patent number: 10800771
    Abstract: The present invention is related to an improved process for the preparation of dasatinib anhydrous crystalline Neat form N-6 with high purity and high yield. The present invention also relates to purification of dasatinib crystalline Neat form N-6.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: October 13, 2020
    Assignee: NATCO PHARMA LIMITED
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Uma Naresh Babu Kotra, Srinivasulu Sakkani, Dharmender Ragidi, Kotayyababu Sikha, Venkaiah Chowdary Nannapaneni
  • Publication number: 20200299248
    Abstract: The present invention relates to novel intermediates of Eribulin and process for the preparation of the same. The process of the present invention is commercially viable and can be easily adopted for plant scale operations. The present invention relates to tetrahydrofuran compounds of formula I, X, XI, D and B.
    Type: Application
    Filed: November 20, 2018
    Publication date: September 24, 2020
    Inventors: Bulli Babi VIPPARLA, Sreenivas NAGAPURI, Sathaiah KANDULA, Janaki Rama Rao RAVI, Durga Prasad KONAKANCHI, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI
  • Patent number: 10604505
    Abstract: The present invention is related to an improved process for the preparation of Ceritinib with high yield and high purity. The present process is cost effective and feasible in large scale production also. The present invention also related to a stable amorphous form of Ceritinib and its preparation. The present invention also relates to a process for the preparation of Crystalline form A of Ceritinib.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: March 31, 2020
    Assignee: Natco Pharma Limited
    Inventors: Durga Prasad Konakanchi, Subba Rao Pula, Muni Bhaskar Pallooru, Radha Rani Samatham, Ramakrishna Pilli, Lakshmana Viswa Venkata Pavan Kumar Maddula, Sandeep Karnam, Pulla Reddy Muddasani, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Publication number: 20200095249
    Abstract: The present invention relates to a process for the preparation of stable and 5 pure amorphous form of Idelalisib. Further, the present process is simple, more economical, cost effective and efficient method of manufacturing that is suitable for industrial scale-up having a high degree of chromatographic purity.
    Type: Application
    Filed: April 11, 2018
    Publication date: March 26, 2020
    Inventors: Amala KOMPELLA, Sreenivas RACHAKONDA, Venugopala Krishna GAMPA, Subhash KUSUMBA, Durga Prasad KONAKANCHI, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI
  • Publication number: 20190292177
    Abstract: The present invention is related to an improved process for the preparation of dasatinib anhydrous crystalline Neat form N-6 with high purity and high yield. The present invention also relates to purification of dasatinib crystalline Neat form N-6.
    Type: Application
    Filed: March 20, 2017
    Publication date: September 26, 2019
    Inventors: Durga Prasad KONAKANCHI, Buchappa GONGALLA, Uma Naresh Babu KOTRA, Srinivasulu SAKKANI, Dharmender RAGIDI, Kotayyababu SIKHA, Venkaiah Chowdary NANNAPANENI
  • Publication number: 20190233389
    Abstract: The present invention is related to an improved process for the preparation of Pomalidomide with higher yields and high purity. Particularly the present invention relates to form A preparation of Pomalidomide and its purification, wherein the present process doesn't involve use of dioxane solvent and avoids higher temperatures.
    Type: Application
    Filed: August 22, 2016
    Publication date: August 1, 2019
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Dharmendher Ragidi, Uma Naresh Babu Kotra, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Publication number: 20190047983
    Abstract: The present invention is related to an improved process for the preparation of Ceritinib with high yield and high purity. The present process is cost effective and feasible in large scale production also. The present invention also related to a stable amorphous form of Ceritinib and its preparation. The present invention also relates to a process for the preparation of Crystalline form A of Ceritinib.
    Type: Application
    Filed: March 9, 2017
    Publication date: February 14, 2019
    Inventors: Durga Prasad Konakanchi, Subba Rao Pula, Muni Bhaskar Pallooru, Radha Rani Samatham, Ramakrishna Pilli, Lakhmana Viswa Venjata Pavan Kumar Maddula, Sandeep Karnam, Pulla Reddy Muddasani, Kali Satya Bhujanga Rao Ibhatla, Venkaiah Chowdary Napaneni
  • Patent number: 10106554
    Abstract: The present invention relates to novel series of substituted 7-(morpholinyl)-2-(N-piperazinyl)-methyl thieno [2, 3-c] pyridines of the following structure of formula I. Where in R1, R2, R3 and R4 are defined.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: October 23, 2018
    Assignee: NATCO PHARMA LIMITED
    Inventors: Durga Prasad Konakanchi, Subba Rao Pula, Rama Krishna Pilli, Lakshmana Viswa Venkata Pavan Kumar Maddula, Srinivasa Krishna Murthy Konduri, Janaki Rama Rao Ravi, Naga Vasanta Srinivasu Vuppalapati, Sandeep Kumar Thoota, Pulla Reddy Muddasani, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Patent number: 10040778
    Abstract: Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: August 7, 2018
    Assignee: NATCO PHARMA LIMITED
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Kotayya Babu Sikha, Chandrasekar Kandaswamy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Publication number: 20170320891
    Abstract: The present invention relates to novel series of substituted 7-(morpholinyl)-2-(N-piperazinyl)-methyl thieno [2, 3-c] pyridines of the following structure of formula I. Where in R1, R2, R3 and R4 are defined.
    Type: Application
    Filed: December 11, 2014
    Publication date: November 9, 2017
    Inventors: Durga Prasad KONAKANCHI, Subba Rao PULA, Rama Krishna PILLI, Lakshmana Viswa Venkata Pavan Kumar MADDULA, Srinivasa Krishna Murthy KONDURI, Janaki Rama Rao RAVI, Naga Vasanta Srinivasu VUPPALAPATI, Sandeep Kumar THOOTA, Pulla Reddy MUDDASANI, Kali Satya Bhujanga Rao ADIBHATLA, Venkaiah Chowdary NANNAPANENI
  • Publication number: 20150353525
    Abstract: Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.
    Type: Application
    Filed: July 8, 2015
    Publication date: December 10, 2015
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Kotayya Babu Sikha, Chandrasekar Kandaswamy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni