Patents by Inventor Dustin Little

Dustin Little has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Soluble bacterial and fungal proteins and methods and uses thereof in inhibiting and dispersing biofilm
    Patent number: 11672846
    Abstract: The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: June 13, 2023
    Assignees: The Hospital for Sick Children, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Lynne P. Howell, Perrin Baker, Noor Alnabelseya, Natalie Bamford, Dustin Little, Donald Sheppard, Brendan Snarr, Mark Jae Lee
  • SOLUBLE BACTERIAL AND FUNGAL PROTEINS AND METHODS AND USES THEREOF IN INHIBITING AND DISPERSING BIOFILM
    Publication number: 20210138044
    Abstract: The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.
    Type: Application
    Filed: December 18, 2020
    Publication date: May 13, 2021
    Inventors: Lynne P. HOWELL, Perrin BAKER, Noor ALNABELSEYA, Natalie BAMFORD, Dustin LITTLE, Donald SHEPPARD, Brendan SNARR, Mark Jae LEE
  • Soluble bacterial and fungal proteins and methods and uses thereof in inhibiting and dispersing biofilm
    Patent number: 10905749
    Abstract: The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: February 2, 2021
    Assignees: The Hospital for Sick Children, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Lynne Howell, Perrin Baker, Noor Alnabelseya, Natalie Bamford, Dustin Little, Donald Sheppard, Brendan Snarr, Mark Jae Lee
  • SOLUBLE BACTERIAL AND FUNGAL PROTEINS AND METHODS AND USES THEREOF IN INHIBITING AND DISPERSING BIOFILM
    Publication number: 20170216410
    Abstract: The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.
    Type: Application
    Filed: June 5, 2015
    Publication date: August 3, 2017
    Inventors: Lynne Howell, Perrin Baker, Noor Alnabelseya, Natalie Bamford, Dustin Little, Donald Sheppard, Brendan Snarr, Mark Jae Lee