Patents by Inventor Earl A. Christensen

Earl A. Christensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10022408
    Abstract: The present invention relates to novel isolated strains of Bifidobacterium adolescentis which are capable of i) increasing the trans-epithelial electrical resistance (TER) of a Caco-2 cell monolayer after 10 h treatment to more than 120% of TER at treatment start, ii) inducing secretion of >200 pg/ml of IL-10, and/or iii) inducing an IL-10:IL-12 ratio >1 when co-incubated with human PBMC derived dendritic cells. The strains may have one, two or all three of these capabilities. The present invention relates to the use of these novel strains for the in prevention, alleviation of symptoms, and treatment of diseases or conditions with an underlying impaired intestinal barrier function and pro-inflammatory activation of the mucosa.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: July 17, 2018
    Assignee: CHR. Hansen A/S
    Inventors: Thomas Dyrmann Leser, Dorte Myling-Petersen, Jeffrey Earl Christensen, Anja Wellejus, Elke Brockmann
  • Publication number: 20170252382
    Abstract: The present invention relates to novel isolated strains of Bifidobacterium adolescentis which are capable of i) increasing the trans-epithelial electrical resistance (TER) of a Caco-2 cell monolayer after 10 h treatment to more than 120% of TER at treatment start, ii) inducing secretion of >200 pg/ml of IL-10, and/or iii) inducing an IL-10:IL-12 ratio>1 when co-incubated with human PBMC derived dendritic cells. The strains may have one, two or all three of these capabilities. The present invention relates to the use of these novel strains for the in prevention, alleviation of symptoms, and treatment of diseases or conditions with an underlying impaired intestinal barrier function and pro-inflammatory activation of the mucosa.
    Type: Application
    Filed: August 28, 2015
    Publication date: September 7, 2017
    Applicant: CHR. HANSEN A/S
    Inventors: THOMAS DYRMANN LESER, Dorte MYLING-PETERSEN, Jeffrey Earl CHRISTENSEN, Anja WELLEJUS, Elke BROCKMANN
  • Patent number: 4232661
    Abstract: A vibrator motor is coupled to the frame of a body support structure to vibrate the latter. The motor is energized by a train of triangular pulses modulated by a triangular pulse signal having a lower frequency than that of the triangular pulse train.
    Type: Grant
    Filed: February 8, 1978
    Date of Patent: November 11, 1980
    Inventor: Earl A. Christensen
  • Patent number: D255799
    Type: Grant
    Filed: November 11, 1977
    Date of Patent: July 8, 1980
    Inventor: Earl Christensen
  • Patent number: RE31603
    Abstract: A vibrator motor is coupled to the frame of a body support structure to vibrate the latter. The motor is energized by a train of triangular pulses modulated by a triangular pulse signal having a lower frequency than that of the triangular pulse train.
    Type: Grant
    Filed: November 8, 1982
    Date of Patent: June 19, 1984
    Assignee: Andrew Electronics of Northern Calif., Inc.
    Inventor: Earl A. Christensen