Patents by Inventor Edib Jakupovic

Edib Jakupovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6221398
    Abstract: A process for producing a pharmaceutical powder for inhalation comprising crystalline particles of an inhalation compound, comprising dissolving an inhalation compound in a solvent; and introducing the solution containing the inhalation compound in droplet form or as a jet stream into an anti-solvent which is miscible with the solvent and which is under agitation.
    Type: Grant
    Filed: July 10, 1996
    Date of Patent: April 24, 2001
    Assignee: Astra Aktiebolag
    Inventors: Edib Jakupovic, Jan Trofast
  • Patent number: 6017959
    Abstract: New hydrated salts of N,N'-diacetylcystine are described, as well as processes for the preparation thereof.
    Type: Grant
    Filed: December 18, 1997
    Date of Patent: January 25, 2000
    Assignee: Astra Aktiebolag
    Inventors: Edib Jakupovic, Eric Teneberg
  • Patent number: 5874063
    Abstract: There are described finely divided particles of a pharmaceutical substance, wherein the substance when submitted to water vapor gives off heat of less than 1.2 Joules per gram, processes for their production and pharmaceutical formulations containing them.
    Type: Grant
    Filed: February 26, 1996
    Date of Patent: February 23, 1999
    Assignee: Astra Aktiebolag
    Inventors: Lars-Erik Briggner, Katarina Bystrom, Edib Jakupovic, Eva Trofast, Jan Trofast
  • Patent number: 5804582
    Abstract: New crystalline organic salts of N,N'-diacetyl cystine with immunomodulating effect, processes for their preparation, pharmaceutical compositions containing them and methods of their pharmacological use.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 8, 1998
    Assignee: Astra Aktiebolag
    Inventors: Carl-Magnus Alexander Andersson, H.ang.kan Sten Axel Magnus Bergstrand, Edib Jakupovic, Bo-Goran Josefsson, Magnus Leif Lindvall, Bengt Olof Sarnstrand, Eric Nils Gunnar Teneberg
  • Patent number: 5693858
    Abstract: New crystalline organic salts of N,N'-diacetyl cystine with immunomodulating effect, processes for their preparation, pharmaceutical compositions containing them and methods of their pharmacological use.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: December 2, 1997
    Assignee: Astra Aktiebolag
    Inventors: Edib Jakupovic, Eric Nils Gunnar Teneberg
  • Patent number: 5650538
    Abstract: New crystalline organic salts of N,N'-diacetyl cystine with immunomodulating effect, processes for their preparation, pharmaceutical compositions containing them and methods of their pharmacological use.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 22, 1997
    Assignee: Astra Aktiebolag
    Inventors: Edib Jakupovic, Eric Nils Gunnar Teneberg
  • Patent number: 5591889
    Abstract: The present invention relates to a method for the synthesis of foscarnet, i.e. trisodium phosphonoformate hexahydrate, comprising the steps of adding sodium hydroxide to water, heating the aqueous sodium hydroxide solution to 50.degree. C., adding triethyl phosphonoformate to said solution at 50.degree. C., heating the reaction mixture to reflux for about 1 hour, cooling of the reaction mixture and filtering-off of the product.
    Type: Grant
    Filed: April 18, 1995
    Date of Patent: January 7, 1997
    Assignee: Aktiebolaget Astra
    Inventors: Edib Jakupovic, Jan Stenhede
  • Patent number: 5562923
    Abstract: A process for providing water-soluble micronized pharmaceutically acceptable inhalable substances, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation of the pharmaceutically acceptable substances. This process is carried out by the steps of reducing, if necessary, the residual water from the micronized substance by drying at an elevated temperature and/or vacuum; conditioning the dried, micronized pharmaceutically acceptable inhalable substances with a solvent; and eliminating residual solvent by storing under dry conditions as, e.g., in a vacuum or by purging with a dry, inert gas.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 8, 1996
    Assignee: Aktiebolaget Astra
    Inventors: Jan W. Trofast, Eva A. Trofast, Edib Jakupovic, Katarina U. Bystrom
  • Patent number: 5434304
    Abstract: The present invention is directed to a process for preparing formoterol and related compounds and derivatives thereof and their pharmacologically and pharmaceutically acceptable fumarate salts and/or solvates. The present invention is also directed to certain formoterol related compounds per se.
    Type: Grant
    Filed: September 20, 1994
    Date of Patent: July 18, 1995
    Assignee: Aktiebolaget Astra
    Inventors: Jan W. Trofast, Edib Jakupovic, Katarina L. Mansson
  • Patent number: 5385904
    Abstract: New crystalline organic salts of N,N'-diacetyl cystine with immunomodulating effect, processes for their preparation, pharmaceutical compositions containing them and methods of their pharmacological use.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: January 31, 1995
    Assignee: Aktiebolaget Astra
    Inventors: Carl-Magnus A. Andersson, Hakan S. A. M. Bergstrand, Edib Jakupovic, Bo-Goran Josefsson, Magnus L. Lindvall, Bengt O. Sarnstrand, Eric N. G. Teneberg
  • Patent number: 4925933
    Abstract: A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives characterized in reaction of a corresponding 16,17-acetonide with an aldehyde or ketone in (a) hydrocarbon solvent wherein the solubility of the pregnane derivative is less than 1 mg/l or in a halogenated hydrocarbon solvent together with a hydrohalogen acid or an organic sulphonic acid as catalyst and in the presence of small grains of an insert material in the reaction medium or (b) a halogenated hydrocarbon solvent together with a hydrohalogen acid an organic sulphonic acid as catalyst and in the presence of an epimeric distribution modifier.
    Type: Grant
    Filed: September 11, 1987
    Date of Patent: May 15, 1990
    Assignee: Astra Pharmaceutical Production Aktiebolag
    Inventors: Edib Jakupovic, Roy T. Sourander, Jan U. Stenhede, Rolf P. Svensson