Patents by Inventor Edit SZABÓ

Edit SZABÓ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLUORESCENT DYE ACCUMULATION ASSAY
    Publication number: 20200284797
    Abstract: ABC multidrug transporters are key players in cancer multidrug resistance and in general xenobiotic elimination, thus their functional assays provide important tools for research and diagnostic applications. It has been found that in cells expressing functional ABCG2, ABCB1, or ABCC1 transporters, cellular PG fluorescence is strongly reduced. The invention relates to methods and uses of fluorescein derivative ester compounds of formula Ia which are analogs of PG for assessing ABC transporter activity of ABC multidrug transporters. The present accumulation assay is a novel tool for the parallel determination of the function of the multidrug transporters, in particular ABCG2, ABCB1, and ABCC1. The assay is applicable for diagnostic purposes and also allows the selection, separation and culturing of selected cell populations expressing such transporters.
    Type: Application
    Filed: October 25, 2018
    Publication date: September 10, 2020
    Inventors: Edit SZABÓ, Dóra KOVÁCS-TÜRK, Ágnes TELBISZ, Nóra KUCSMA, Tamás HORVÁTH, Gergely SZAKÁCS, László HOMOLYA, Balázs SARKADI, VÁRADY György
  • Novel GnRH analogues with antitumour effects and pharmaceutical compositions thereof
    Publication number: 20060189539
    Abstract: The present invention provides peptides and pharmacologically active compounds including gonadotropin-releasing hormone (GnRH) analogues according to formulas of the invention, wherein the compounds show an antitumour effect. The invention additionally provides compositions including these peptides and compounds.
    Type: Application
    Filed: October 28, 2003
    Publication date: August 24, 2006
    Inventors: Sandor Lovas, Richard Murphy, Geza Toth, Adrienn Kalnay, Dezso Gaal, Istvan Palyi, Gizella Turi, Borbala Vincze, Imre Mezom, Henrietta Tanai, Zsolt Vadasz, Istvan Teplan, Janos Seprodi, Edit Szabo, Janos Pato, Melinda Mora