Abstract: Provided herein are methods for aligning raw genetic sequence data generated by a sequencing device. Also provided herein are methods and systems for quantifying the probability that possible alignments for one or more read pairs are correct, for calling known variants, and for detecting novel structural variants.

Abstract: A toilet seal for sealing between a plumbing fixture discharge and a waste drainpipe outlet is described. The toilet seal comprises a flange member having an inwardly extending flexible lip. A flexible sleeve extends downwardly from the flange member. The toilet seal further includes a compressible member having an upper surface disposed adjacent to a lower surface of the flange member. The compressible member further has a lower surface and a plurality of ridges extend downwardly from the lower surface of the compressible member.

Abstract: The present disclosure relates to a method for manufacturing a nestable water tank, the method comprising molding a water tank comprising a hollow cylindrical body and cutting the water tank to form the nestable water tank comprising a tank body and a lid, wherein the tank body comprises: a side wall comprising a cylindrical shape running along a vertical axis, an interior surface, and an exterior surface; and a bottom connected to a bottom portion of the cylindrical tank, together forming a nestable water tank interior space capable of storing water within the nestable water tank interior space and comprising an interior bottom surface and an exterior bottom surface, wherein at least one of the tank body and the lid are each nestable with other similarly shaped tank bodies and lids.

Abstract: The present disclosure generally relates to flexible drainage trap assemblies and methods for constructing and installing such drainage traps. In one exemplary embodiment, a flexible drainage trap assembly includes a plumbing fixture connector, a discharge joint, and a trap portion connecting the plumbing fixture connector and discharge joint. The trap portion is shaped in such a way that it is operable to retain a pool of water inside the trap portion. The disclosed flexible drainage assemblies include a flexible portion that has a substantially smooth inner surface.

Abstract: A toilet seal for sealing between a plumbing fixture discharge and a waste drainpipe outlet is described. The toilet seal comprises a flange member having an inwardly extending flexible lip. A flexible sleeve extends downwardly from the flange member. The toilet seal further includes a compressible member having an upper surface disposed adjacent to a lower surface of the flange member. The compressible member further has a lower surface and a plurality of ridges extend downwardly from the lower surface of the compressible member.

Abstract: A toilet seal for sealing between a plumbing fixture discharge and a waste drainpipe outlet is described. The toilet seal comprises a flange member having an inwardly extending flexible lip. A flexible sleeve extends downwardly from the flange member. The toilet seal further includes a compressible member having an upper surface disposed adjacent to a lower surface of the flange member. The compressible member further has a lower surface and a plurality of ridges extend downwardly from the lower surface of the compressible member.

Abstract: The present disclosure generally relates to flexible drainage trap assemblies and methods for constructing and installing such drainage traps. In one exemplary embodiment, a flexible drainage trap assembly includes a plumbing fixture connector, a discharge joint, and a trap portion connecting the plumbing fixture connector and discharge joint. The trap portion is shaped in such a way that it is operable to retain a pool of water inside the trap portion. The disclosed flexibly: drainage assemblies include a flexible portion that has a substantially smooth inner surface.

Abstract: The present disclosure generally relates to flexible drainage trap assemblies and methods for constructing and installing such drainage traps. In one exemplary embodiment, a flexible drainage trap assembly includes a plumbing fixture connector, a discharge joint, and a trap portion connecting the plumbing fixture connector and discharge joint. The trap portion is shaped in such a way that it is operable to retain a pool of water inside the trap portion. The disclosed flexible drainage assemblies include a flexible portion that has a substantially smooth inner surface.

Abstract: The present disclosure generally relates to improved water closet flanges and methods for installing such water closet flanges. In one exemplary embodiment, an improved water closet flange apparatus includes an outer flange and a flexible conduit portion (i.e. sleeve) extending downwardly therefrom. The flexible sleeve has a sufficient degree of flexibility to accommodate connection between offset, misaligned, angled, or otherwise incongruous plumbing fixture discharges and waste drain pipe outlets. In one embodiment, the flexible sleeve includes at least one corrugated portion to aid the desired flexibility. An upper portion of the flexible sleeve may include an inwardly extending lip portion to accommodate the desired seal between the plumbing fixture discharge and the flange apparatus. Related methods for installing the disclosed flange apparatus between plumbing fixture discharges and waste drainpipes are also described.

Abstract: Provided herein are methods for aligning raw genetic sequence data generated by a sequencing device. Also provided herein are methods and systems for quantifying the probability that possible alignments for one or more read pairs are correct, for calling known variants, and for detecting novel structural variants.

Abstract: A toilet seal for sealing between a plumbing fixture discharge and a waste drainpipe outlet is described. The toilet seal comprises a flange member having an inwardly extending flexible lip and one or more raised ridges defining an annular seal extending upwardly from an upper surface of the flange member. The toilet seal further includes a radiused wall extending downwardly from the flange member, which cooperates with the flange member to define a cavity for receiving a compressible member. The toilet seal further comprises a flexible sleeve extending downwardly from the radiused wall. Related methods are described.

Abstract: The present disclosure generally relates to improved water closet flanges and methods for installing such water closet flanges. In one exemplary embodiment, an improved water closet flange apparatus includes an outer flange and a flexible conduit portion (i.e. sleeve) extending downwardly therefrom. The flexible sleeve has a sufficient degree of flexibility to accommodate connection between offset, misaligned, angled, or otherwise incongruous plumbing fixture discharges and waste drain pipe outlets. In one embodiment, the flexible sleeve includes at least one corrugated portion to aid the desired flexibility. An upper portion of the flexible sleeve may include an inwardly extending lip portion to accommodate the desired seal between the plumbing fixture discharge and the flange apparatus. Related methods for installing the disclosed flange apparatus between plumbing fixture discharges and waste drainpipes are also described.

Abstract: The present disclosure generally relates to flexible drainage trap assemblies and methods for constructing and installing such drainage traps. In one exemplary embodiment, a flexible drainage trap assembly includes a plumbing fixture connector, a discharge joint, and a trap portion connecting the plumbing fixture connector and discharge joint. The trap portion is shaped in such a way that it is operable to retain a pool of water inside the trap portion. The disclosed flexible drainage assemblies include a flexible portion that has a substantially smooth inner surface.

Abstract: A method of installing a drain fixture, the method comprising first installing a sub-floor plumbing system comprising a plumbing trap, a removable drain pipe, and a sleeve. Next, the method comprises connecting the plumbing trap and the removable drain pipe and sliding the sleeve over the removable drain pipe. Next, the method comprises building a flooring surface proximate to the plumbing trap, the removable drain pipe, and the sleeve. Then, the method comprises removing the removable drain pipe at least partly from the sleeve, cutting the removable drain pipe to the desired length, and re-inserting the removable drain pipe through the sleeve and into the plumbing trap.

Abstract: A toilet seal for sealing between a plumbing fixture discharge and a waste drainpipe outlet is described. The toilet seal comprises a flange member having an inwardly extending flexible lip. A flexible sleeve extends downwardly from the flange member. The toilet seal further includes a compressible member having an upper surface disposed adjacent to a lower surface of the flange member. The compressible member further has a lower surface and a plurality of ridges extend downwardly from the lower surface of the compressible member.

Abstract: The present disclosure generally relates to improved water closet flanges and methods for installing such water closet flanges. In one exemplary embodiment, an improved water closet flange apparatus includes an outer flange and a flexible conduit portion (i.e. sleeve) extending downwardly therefrom. The flexible sleeve has a sufficient degree of flexibility to accommodate connection between offset, misaligned, angled, or otherwise incongruous plumbing fixture discharges and waste drain pipe outlets. In one embodiment, the flexible sleeve includes at least one corrugated portion to aid the desired flexibility. An upper portion of the flexible sleeve may include an inwardly extending lip portion to accommodate the desired seal between the plumbing fixture discharge and the flange apparatus. Related methods for installing the disclosed flange apparatus between plumbing fixture discharges and waste drainpipes are also described.

Abstract: A reinforced hose includes a tube and a braided sleeve disposed about an outside of the tube. The braided sleeve includes a plurality of bundles. A bundle may be defined as a plurality of threads extending along a same path of a braiding pattern of the braided sleeve. At least one of the bundles includes a metallic thread and a non-metallic thread.