Patents by Inventor Edward B. McCauley

Edward B. McCauley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8308854
    Abstract: A system for recycling helium carrier gas comprises: a bladder, the bladder interior fluidically configured so as to receive helium-bearing gas output from at least one of a split vent and a septum purge vent of a gas chromatograph; a compartment containing the bladder; a source of pressurized air or gas operable so as to supply pressurized air or gas into the compartment interior so as to compress the bladder containing the helium-bearing gas; a gas reservoir fluidically coupled to the bladder interior so as to receive the helium bearing gas from the compressed bladder interior; and at least one gas purification module configured so as to receive the helium-bearing gas from the gas reservoir and operable to remove contaminants from the helium-bearing gas, an output of the at least one gas purification module being fluidically coupled to a carrier gas inlet of the gas chromatograph.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: November 13, 2012
    Assignee: Thermo Finnigan LLC
    Inventors: Edward B. McCauley, Matt A. Lasater
  • Publication number: 20120103064
    Abstract: A device for conserving helium gas in a gas chromatograph system is characterized in that during the majority of an analytical separation, helium is used as the carrier gas while an auxiliary non-helium gas is used to pressurize the inlet and provide for septum purge and split vent flow. Prior an injection period, a coaxial helium flow is established at the column entrance wherein the coaxial helium flow is less than the column flow. Following the injection and sample transfer period, a coaxial helium flow is established wherein the flow is greater than the column flow.
    Type: Application
    Filed: October 27, 2010
    Publication date: May 3, 2012
    Inventors: Edward B. McCauley, Paolo Magni
  • Patent number: 8141411
    Abstract: A method for determining a low cylinder pressure condition of a gas chromatograph includes providing gas from the cylinder to an inlet of the gas chromatograph. In particular, the gas is provided at a predetermined inlet pressure that is higher than an inlet pressure that is required for a predetermined gas chromatographic analysis routine. The inlet pressure of the gas being supplied to the inlet is increased, in order to attempt to achieve a predetermined check value. It is then determined if the inlet pressure actually increases to at least the predetermined check value. If it is determined that the inlet pressure of the gas does not increase to at least the predetermined check value, then an indication of a low cylinder pressure condition is provided.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: March 27, 2012
    Assignee: Thermo Finnigan LLC
    Inventor: Edward B. McCauley
  • Publication number: 20110138877
    Abstract: A system for recycling helium carrier gas comprises: a bladder, the bladder interior fluidically configured so as to receive helium-bearing gas output from at least one of a split vent and a septum purge vent of a gas chromatograph; a compartment containing the bladder; a source of pressurized air or gas operable so as to supply pressurized air or gas into the compartment interior so as to compress the bladder containing the helium-bearing gas; a gas reservoir fluidically coupled to the bladder interior so as to receive the helium bearing gas from the compressed bladder interior; and at least one gas purification module configured so as to receive the helium-bearing gas from the gas reservoir and operable to remove contaminants from the helium-bearing gas, an output of the at least one gas purification module being fluidically coupled to a carrier gas inlet of the gas chromatograph.
    Type: Application
    Filed: December 15, 2009
    Publication date: June 16, 2011
    Inventors: Edward B. McCauley, Matt A. Lasater
  • Publication number: 20100223978
    Abstract: A system for interfacing a gas chromatograph (GC) to a mass spectrometer the GC comprising a GC column partially contained within a GC oven, the mass spectrometer comprising a housing enclosing an interior having an ion source, the system comprising: a conduit extending from the GC oven to the mass spectrometer and comprising an interior volume that is contiguous with an interior volume of the GC oven; and a duct extending from a region of relatively high or relatively low pressure within the GC oven to the conduit interior volume and operable so as to transmit a flow of air or gas between the region of relatively high or relatively low pressure and the conduit interior volume, wherein a portion of the GC column extends through the conduit interior volume to the ion source.
    Type: Application
    Filed: March 6, 2009
    Publication date: September 9, 2010
    Inventor: Edward B. McCauley
  • Patent number: 7791042
    Abstract: An ion source includes structure having separate first and second ion volumes therein, and electron source structure having first and second portions that selectively supply electrons to the first and second ion volumes, respectively. The electron source structure has a first operational mode in which the second portion substantially prevents a supply of electrons to the second ion volume and in which electrons are supplied to the first ion volume under control of the first portion, and has a second operational mode in which the first portion substantially prevents a supply of electrons to the first ion volume and in which electrons are supplied to the second ion volume under control of the second portion.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: September 7, 2010
    Assignee: Thermo Finnigan LLC
    Inventors: Edward B. McCauley, Scott T. Quarmby
  • Patent number: 7759655
    Abstract: A variable duty cycle ion source assembly is coupled to a continuous beam mass spectrometer. The duty cycle can be adjusted based on previous scan data or real time sampling of ion intensities during mass analysis. This provides the ability to dynamically control the total number of ions formed, mass analyzed and detected for each ion mass of interest. A reflection mechanism that provides a variable duty cycle, enables electrons to be reflected through an ion volume multiple times before atoms or molecules are ionized in the ion volume, thereby providing for dynamic control of the ion population.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: July 20, 2010
    Assignee: Thermo Finnigan LLC
    Inventor: Edward B. McCauley
  • Patent number: 7709790
    Abstract: A method and apparatus of combining an ion volume, a lens stack, and an ion optic that similarly cooperates with a detached multipole ion guide is herein incorporated into a single sub-assembly that can be removed from a mass spectrometer instrument without venting. Such an arrangement allows an operator to clean all parts of the ion path that get contaminated in normal operation, reassemble and reinsert in a timely manner and then pump down to an acceptable vacuum without having to vent the system.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: May 4, 2010
    Assignee: Thermo Finnigan LLC
    Inventors: George B. Guckenberger, Joseph B. Wieck, Edward B. McCauley, Scott T. Quarmby
  • Publication number: 20100077838
    Abstract: A method for determining a low cylinder pressure condition of a gas chromatograph includes providing gas from the cylinder to an inlet of the gas chromatograph. In particular, the gas is provided at a predetermined inlet pressure that is higher than an inlet pressure that is required for a predetermined gas chromatographic analysis routine. The inlet pressure of the gas being supplied to the inlet is increased, in order to attempt to achieve a predetermined check value. It is then determined if the inlet pressure actually increases to at least the predetermined check value. If it is determined that the inlet pressure of the gas does not increase to at least the predetermined check value, then an indication of a low cylinder pressure condition is provided.
    Type: Application
    Filed: September 30, 2008
    Publication date: April 1, 2010
    Inventor: Edward B. McCauley
  • Patent number: 7622713
    Abstract: A method for operating a mass spectrometer includes determining a first performance characteristic while operating the mass spectrometer with a first electron emitter, storing first information relating to the first performance characteristic, determining a second performance characteristic while operating the mass spectrometer with a second electron emitter, storing second information relating to the second performance characteristic, and thereafter switching from operation using the first electron emitter to operation using the second electron emitter. The switching includes using the first and second information to normalize performance of the second electron emitter after the switching relative to performance of the first electron emitter before the switching.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: November 24, 2009
    Assignee: Thermo Finnigan LLC
    Inventors: Scott T. Quarmby, George B. Guckenberger, Edward B. McCauley
  • Publication number: 20090242747
    Abstract: A method and apparatus of combining an ion volume, a lens stack, and an ion optic that similarly cooperates with a detached multipole ion guide is herein incorporated into a single sub-assembly that can be removed from a mass spectrometer instrument without venting. Such an arrangement allows an operator to clean all parts of the ion path that get contaminated in normal operation, reassemble and reinsert in a timely manner and then pump down to an acceptable vacuum without having to vent the system.
    Type: Application
    Filed: April 1, 2008
    Publication date: October 1, 2009
    Inventors: George B. Guckenberger, Joseph B. Wieck, Edward B. McCauley, Scott T. Quarmby
  • Publication number: 20090194680
    Abstract: A method for operating a mass spectrometer includes determining a first performance characteristic while operating the mass spectrometer with a first electron emitter, storing first information relating to the first performance characteristic, determining a second performance characteristic while operating the mass spectrometer with a second electron emitter, storing second information relating to the second performance characteristic, and thereafter switching from operation using the first electron emitter to operation using the second electron emitter. The switching includes using the first and second information to normalize performance of the second electron emitter after the switching relative to performance of the first electron emitter before the switching.
    Type: Application
    Filed: February 5, 2008
    Publication date: August 6, 2009
    Inventors: Scott T. Quarmby, George B. Guckenberger, Edward B. McCauley
  • Publication number: 20090194681
    Abstract: A mass spectrometer and a technique for operating it involve setting an operating parameter that influences a rate of flow of electrons from an electron source into an ion volume so that ions produced from a material in the ion volume in response to electrons satisfy an ion production target, performing a plurality of analytical runs using the mass spectrometer with the electron source while monitoring an operational characteristic, and adjusting the operating parameter in response to the monitoring to compensate for a change over time in the operational characteristic in a manner so that the ion production target remains satisfied.
    Type: Application
    Filed: February 5, 2008
    Publication date: August 6, 2009
    Inventor: Edward B. McCauley
  • Patent number: 7507954
    Abstract: A variable duty cycle ion source assembly is coupled to a continuous beam mass spectrometer. The duty cycle can be adjusted based on previous scan data or real time sampling of ion intensities during mass analysis. This provides the ability to control the total number of ions formed, mass analyzed and detected for each ion mass of interest. The frequency of the ion source can be sufficiently high (kHz range) so as to maintain accurate peak centroiding. The ion source assembly can be used for both electron ionization (EI) or chemical ionization (CI) modes of operation.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: March 24, 2009
    Assignee: Thermo Finnigan LLC
    Inventors: Edward B. McCauley, Scott T. Quarmby, George B. Guckenberger
  • Publication number: 20080116369
    Abstract: An ion source includes structure having separate first and second ion volumes therein, and electron source structure having first and second portions that selectively supply electrons to the first and second ion volumes, respectively. The electron source structure has a first operational mode in which the second portion substantially prevents a supply of electrons to the second ion volume and in which electrons are supplied to the first ion volume under control of the first portion, and has a second operational mode in which the first portion substantially prevents a supply of electrons to the first ion volume and in which electrons are supplied to the second ion volume under control of the second portion.
    Type: Application
    Filed: November 17, 2006
    Publication date: May 22, 2008
    Inventors: Edward B. McCauley, Scott T. Quarmby
  • Patent number: 7323682
    Abstract: A variable duty cycle ion source assembly is coupled to a continuous beam mass spectrometer. The duty cycle can be adjusted based on previous scan data or real time sampling of ion intensities during mass analysis. This provides the ability to control the total number of ions formed, mass analyzed and detected for each ion mass of interest. The frequency of the ion source can be sufficiently high (kHz range) so as to maintain accurate peak centroiding. The ion source assembly can be used for both electron ionization (EI) or chemical ionization (CI) modes of operation.
    Type: Grant
    Filed: March 15, 2005
    Date of Patent: January 29, 2008
    Assignee: Thermo Finnigan LLC
    Inventors: Edward B. McCauley, Scott T. Quarmby, George B. Guckenberger
  • Publication number: 20070148020
    Abstract: An apparatus and method for differential pumping of a mass spectrometer or other ion-optical device provides a transverse pressure drop introduced across a face of a primary rotor of a turbomolecular pump by placement of one or more partitions in close proximity to the face of the primary rotor. Thus, two or more regions of space within the vacuum chamber having respective different pressures is achieved with a single pump.
    Type: Application
    Filed: December 6, 2006
    Publication date: June 28, 2007
    Inventor: Edward B. McCauley
  • Patent number: 6635885
    Abstract: An apparatus for delivering calibrant gas at selected flow rates to the ionization region of a mass spectrometer which employs capillary flow restrictors for metering the flow.
    Type: Grant
    Filed: January 17, 2001
    Date of Patent: October 21, 2003
    Assignee: Thermo Finnigan LLC
    Inventors: Edward B. McCauley, George B. Guckenberger
  • Patent number: 6593569
    Abstract: Apparatus and method for delivering collisional gas to a mass spectrometer at a desired flow rate which employs a capillary flow restrictor having internal diameter and length selected to provide the desired flow rate.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: July 15, 2003
    Assignee: Thermo Finnigan LLC
    Inventor: Edward B. McCauley
  • Publication number: 20020104965
    Abstract: Apparatus and method for delivering collisional gas to a mass spectrometer at a desired flow rate which employs a capillary flow restrictor having internal diameter and length selected to provide the desired flow rate.
    Type: Application
    Filed: February 8, 2001
    Publication date: August 8, 2002
    Applicant: Finnigan Corporation
    Inventor: Edward B. McCauley