Patents by Inventor Edward Bernard Brown, III

Edward Bernard Brown, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus to diagnose the metastatic or progressive potential of cancer, fibrosis and other diseases
    Patent number: 10765376
    Abstract: A method and apparatus for determining the progressive potential of a disease is disclosed. The forward to backward propagating second harmonic generation signal derived from a second harmonic generation instrument is used to assess the collagen microstructure of imaged body tissue by way of numerical values that are in turn used to determine the progressive or metastatic potential of the disease. The disease may, for example, be a cancer such as breast cancer, lung fibrosis, colorectal adenocarcinoma, or the like. The apparatus may include in vivo instruments or laboratory diagnostic instruments with methods disclosed herein.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: September 8, 2020
    Assignee: University of Rochester
    Inventors: Edward Bernard Brown, III, Seth Warrington Perry, Kathleen Anne Burke, Robert Matthew Kottmann, Patricia Janet Sime, Jesse Wakefield Sharp
  • Method And Apparatus To Diagnose The Metastatic Or Progressive Potential Of Cancer, Fibrosis And Other Diseases
    Publication number: 20170020462
    Abstract: A method and apparatus for determining the progressive potential of a disease is disclosed. The forward to backward propagating second harmonic generation signal derived from a second harmonic generation instrument is used to assess the collagen microstructure of imaged body tissue by way of numerical values that are in turn used to determine the progressive or metastatic potential of the disease. The disease may, for example, be a cancer such as breast cancer, lung fibrosis, colorectal adenocarcinoma, or the like. The apparatus may include in vivo instruments or laboratory diagnostic instruments with methods disclosed herein.
    Type: Application
    Filed: April 7, 2015
    Publication date: January 26, 2017
    Applicant: University of Rochester
    Inventors: Edward Bernard Brown, III, Seth Warrington Perry, Kathleen Anne Burke, Robert Matthew Kottmann, Patricia Janet Sime, Jesse Wakefield Sharp