Patents by Inventor Eishi Tanaka

Eishi Tanaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8026239
    Abstract: A method of treating a malignant tumor selected from the group consisting of leukemia, colorectal cancer, ovarian cancer, oral cancer, lung carcinoma, breast carcinoma, prostate carcinoma, and melanoma by administering to a patient in need thereof an effective amount of at least one compound represented by formula (1) wherein A, X, Q, R1-3, and n are defined herein.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: September 27, 2011
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Publication number: 20100256201
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Application
    Filed: March 11, 2010
    Publication date: October 7, 2010
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Patent number: 7687525
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: March 30, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Patent number: 7595184
    Abstract: The amino acid sequence of a mutant which is obtained by introducing a novel mutation into a Pseudonocardia thermophila JCM3095-derived nitrile hydratase consisting of two types of heterogeneous subunits, and the base sequence of the gene are provided. The nitrile hydratase is modified by specifying the region to be modified in the stereostructure/amino acid sequence of the nitrile hydratase, and applying alteration such as substitution, insertion, deletion or the like, to the amino acids in the amino acid sequence which are corresponding to the amino acid residues forming the region. Also provided is a method for modifying an enzyme having a nitrile hydratase activity.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: September 29, 2009
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Toshifumi Yamaki, Shinichi Banba, Kaori Matoishi, Kiyoshi Ito, Hideki Kobayashi, Eishi Tanaka, Toshihiro Oikawa
  • Publication number: 20080188489
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Application
    Filed: November 14, 2007
    Publication date: August 7, 2008
    Applicant: Schering Aktiengesellschaft
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Patent number: 7317028
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: January 8, 2008
    Assignee: Schering Aktiengesellschaft
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Publication number: 20070009985
    Abstract: The amino acid sequence of a mutant which is obtained by introducing a novel mutation into a Pseudonocardia thermophila JCM3095-derived nitrile hydratase consisting of two types of heterogeneous subunits, and the base sequence of the gene are provided. The nitrile hydratase is modified by specifying the region to be modified in the stereostructure/amino acid sequence of the nitrile hydratase, and applying alteration such as substitution, insertion, deletion or the like, to the amino acids in the amino acid sequence which are corresponding to the amino acid residues forming the region. Also provided is a method for modifying an enzyme having a nitrile hydratase activity.
    Type: Application
    Filed: December 15, 2003
    Publication date: January 11, 2007
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Toshifumi Yamaki, Shinichi Banba, Kaori Matoishi, Kiyoshi Ito, Hideki Kobayashi, Eishi Tanaka, Toshihiro Oikawa
  • Patent number: 6794392
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: September 21, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Patent number: 6174905
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: January 16, 2001
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Patent number: 6011119
    Abstract: A resin composition is provided for an electro-photographic toner. The composition comprises 5 to 95 parts by weight of a high molecular weight vinyl copolymer polymer and 95 to 5 parts by weight of a low molecular weight vinyl copolymer. The former ethylene polymer has a weight average molecular weight (Mw) of from 200,000 to 1,000,000 and a ratio (Mw/Mn) of the weight average molecular weight (Mw) to a number average molecular weight (Mn) of from 8 to 300, and the latter vinyl copolymer has a weight average molecular weight of from 3,000 to 20,000. At least one of the former and latter vinyl copolymer, preferably, the former vinyl copolymer is an ethylene polymer which has been obtained by conducting polymerization in the presence of a monomer having an ionization potential of from 10.0 to 15.0 eV and a difference of from 9.0 to 15.0 eV in level between a highest occupied molecular orbital (HOMO) and a lowest unoccupied molecular orbital (LUMO), both determined by computational chemistry.
    Type: Grant
    Filed: July 19, 1996
    Date of Patent: January 4, 2000
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Katsuru Matsumoto, Nobuhiro Hirayama, Eishi Tanaka, Junko Tobita
  • Patent number: 5023343
    Abstract: There are here provided a novel tetraphenylthiophene derivative represented by the general formula ##STR1## wherein AM is a tertiary amino group, each of l, m and n is the integer 0 or 1 and l.gtoreq.m.gtoreq.n are useful as the charge-transporting material in an electrophotographic photoreceptor having an electrically conductive base and a photosensitive layer thereon containing a charge-transporting material and a charge-generating material, which preferably is an azo compound.
    Type: Grant
    Filed: July 16, 1990
    Date of Patent: June 11, 1991
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Eishi Tanaka, Tsutomu Nishizawa, Yasuyuki Yamada, Hisato Itoh, Akihiro Yamaguchi, Masakatsu Nakatsuka
  • Patent number: 4963449
    Abstract: There are here provided a novel tetraphenylthiophene derivative represented by the general formula ##STR1## wherein AM is a tertiary amino group, each of l, m and n is the integer 0 or 1 and l.gtoreq.m.gtoreq.n are useful as the charge-transporting material in an electrophotographic photoreceptor having an electrically conductive base and a photosensitive layer thereon containing a charge-transporting material and a charge-generating material, which preferably is an azo compound.
    Type: Grant
    Filed: November 17, 1988
    Date of Patent: October 16, 1990
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Eishi Tanaka, Tsutomu Nishizawa, Yasuyuki Yamada, Hisato Itoh, Akihiro yamaguchi, Masakatsu Nakatsuka
  • Patent number: 4931420
    Abstract: A temperature history indicator and its manufacturing method wherein the indicators are formed as chips, labels, tags or the like and accompanied with those goods or their packings which must be stored at a certain temperature or lower and when their storage temperature rises higher than the certain temperature over a not-permissible time period, this fact can be visibly shown by development or change of color caused by chemical matters in the indicator, characterized in that when temperature rises higher than a certain value, a hydrophobic organic compound enclosed in microcapsules melts and diffuses causing a dye-precursor and a color developer, which are prepared independently of the compound, to be contacted with each other to irreversibly achieve color development or change, that this color development or change system is rendered operative when the temperature rise continues to exceed a permissible time period, and that when the tops of the color development or change systems are coated with a transpare
    Type: Grant
    Filed: April 29, 1987
    Date of Patent: June 5, 1990
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Makoto Asano, Haruki Tsutsumi, Eishi Tanaka, Yoshiro Fuseya, Kiyoharu Hasegawa, Hiroyuki Akahori
  • Patent number: 4735744
    Abstract: Disclosed herein is a novel benzoquinone derivative represented by the following general formula (I): ##STR1## wherein R.sub.1 means an alkyl or cycloalkyl group, R.sub.2 denotes an alkyl or cycloalkyl group, a phenyl group which may optionally contain one or more halogen atoms and/or alkyl, cycloalkyl, alkoxy, alkylene, phenoxy, phenyl and/or biphenylyl groups, or a benzyl or naphthyl group which may optionally contain one or more methyl groups. This compound is useful as an oxidative color-developing agent for recording materials.
    Type: Grant
    Filed: May 28, 1985
    Date of Patent: April 5, 1988
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Michihiro Tsujimoto, Kiyoharu Hasegawa, Hiroyuki Akahori, Eishi Tanaka, Makoto Asano
  • Patent number: RE39754
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Grant
    Filed: August 14, 2003
    Date of Patent: July 31, 2007
    Assignee: Schering AG
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka
  • Patent number: RE40703
    Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.
    Type: Grant
    Filed: October 3, 2006
    Date of Patent: April 28, 2009
    Assignee: Schering Aktiengesellschaft
    Inventors: Tsuneji Suzuki, Tomoyuki Ando, Katsutoshi Tsuchiya, Osamu Nakanishi, Akiko Saito, Takashi Yamashita, Yoshinori Shiraishi, Eishi Tanaka