Patents by Inventor Eitan Prisman

Eitan Prisman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11179044
    Abstract: A method of identifying alveolar ventilation (VA) in a subject, the method comprising: (1) using a breathing circuit which, at exhalation, keeps exhaled gas separate from inhaled gas and at inhalation, when a first gas set (FGS) flow is less than the subject's minute ventilation (VE), results in a subject inhaling FGS first and then a second gas set (SGS), for the balance of inhalation; (2) setting the FGS flow at a rate greater that VE; (3) measuring an end tidal CO2 concentration at a steady state; (4) progressively lowering the FGS flow until a time equal to a recirculation time of CO2 in the subject; and (5) deriving VA as the rate of FGS flow at the intersection between an average PETCO2 in a steady state and a line fit to the PETCO2 values after the rise in PETCO2 values begins until the recirculation time.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: November 23, 2021
    Assignee: THORNHILL SCIENTIFIC INC.
    Inventors: Joseph Fisher, David Preiss, Takafumi Azami, Alex Vesely, Eitan Prisman, Ron Somogyi, Steve Iscoe
  • Publication number: 20180344172
    Abstract: An apparatus to measure pulmonary blood flow and cardiac output ({dot over (Q)}) comprising: a) a breathing circuit which, at exhalation, keeps exhaled gas separate from inhaled gas and at inhalation, when VE is greater than first gas set (FGS) flow, results in a subject inhaling FGS first and then a second gas set (SGS), for the balance of inhalation; b) a gas sensor for monitoring gas concentrations at the patient-circuit interface; c) a gas flow control means for controlling the rate of EGS flow into the breathing circuit; d) machine-intelligence consisting of a computer or logic circuit capable of controlling the gas flow control means which receives the output of the gas sensor means and outputs pulmonary blood flow.
    Type: Application
    Filed: February 28, 2018
    Publication date: December 6, 2018
    Applicant: THORNHILL SCIENTIFIC INC.
    Inventors: Joseph Fisher, David Preiss, Takafumi Asami, Alex Vesely, Eitan Prisman, Ron Somogyi, Steve Iscoe
  • Publication number: 20180296158
    Abstract: A breathing circuit for use with a first gas set (FGS) and a second gas set (SGS), said circuit comprising means for keeping separate the FGS and SGS, and a means for sequentially delivering to a patient, first the FGS, and, on inspiration, when the patient inspires so as to deplete the supply of FGS into the circuit, subsequently delivers substantially SGS for the balance of inspiration.
    Type: Application
    Filed: September 29, 2014
    Publication date: October 18, 2018
    Inventors: Joseph Fisher, Eitan Prisman, Takafumi Azami, David Preiss, Alex Vesely, Ron Somogyi, Tehilla Adams, Dan Nayot, Steve Iscoe
  • Publication number: 20160166154
    Abstract: An apparatus to measure pulmonary blood flow and cardiac output (Q) comprising: a) a breathing circuit which, at exhalation, keeps exhaled gas separate from inhaled gas and at inhalation, when VE is greater than first gas set (FGS) flow, results in a subject inhaling FGS first and then a second gas set (SGS), for the balance of inhalation; b) a gas sensor for monitoring gas concentrations at the patient-circuit interface; c) a gas flow control means for controlling the rate of FGS flow into the breathing circuit; d) machine intelligence consisting of a computer or logic circuit capable of controlling the gas flow control means which receives the output of the gas sensor means and outputs pulmonary blood flow.
    Type: Application
    Filed: October 28, 2015
    Publication date: June 16, 2016
    Applicant: THORNHILL SCIENTIFIC INC.
    Inventors: Joseph Fisher, David Preiss, Takafumi Azami, Alex Vesely, Eitan Prisman, Ron Somogyi, Steve Iscoe
  • Patent number: 8844528
    Abstract: A breathing circuit for sequential gas delivery of a first gas set (FGS) and a second gas set (SGS) employs an arrangement of conduits and active or passive valves to prevent mixing of the FGS and SGS including a valve triggered by depletion of FGS that makes the SGS available for inspiration after the FGS is depleted.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: September 30, 2014
    Inventors: Joseph Fisher, David Preiss, Takafumi Azami, Alex Vesely, Eitan Prisman, Steve Iscoe, Ron Somogyi, Dan Nayot, Tehilla Adams
  • Publication number: 20130340756
    Abstract: In a first aspect, the invention relates to an apparatus for inducing or maintaining a target end tidal concentration of a gas in a subject comprising a breathing circuit, a source of gas flow into the circuit, means for controlling the rate of the source of gas flow into the circuit and means for controlling the concentration of gases in the source gas flow independently from each other. In another aspect, the invention relates to a method of preparing an apparatus for inducing or maintaining a target end tidal concentration of a gas X in a subject comprising selecting a rate of a source gas flow into a breathing circuit, selecting the concentration of at least one constituent gas of a component gas making up the source gas to a level corresponding to the end tidal concentration of the gas X, whereby the apparatus is adapted to administer a source gas having a first gas composition.
    Type: Application
    Filed: June 10, 2013
    Publication date: December 26, 2013
    Inventors: MARAT SLESSAREV, JOSEPH FISHER, GEORGE VOLGYESI, EITAN PRISMAN, DAVID MIKULUS, CHRISTOPHER HUDSON, CLIFF ANSEL
  • Patent number: 8459258
    Abstract: In a first aspect, the invention relates to an apparatus for inducing or maintaining a target end tidal concentration of a gas in a subject comprising a breathing circuit, a source of gas flow into the circuit, means for controlling the rate of the source of gas flow into the circuit and means for controlling the concentration of gases in the source gas flow independently from each other. In another aspect, the invention relates to a method of preparing an apparatus for inducing or maintaining a target end tidal concentration of a gas X in a subject comprising selecting a rate of a source gas flow into a breathing circuit, selecting the concentration of at least one constituent gas of a component gas making up the source gas to a level corresponding to the end tidal concentration of the gas X, whereby the apparatus is adapted to administer a source gas having a first gas composition.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: June 11, 2013
    Assignee: Thornhill Scientific Inc.
    Inventors: Marat Slessarev, Joe Fisher, George Volgyesi, Eitan Prisman, David Mikulus, Chris Hudson, Cliff Ansel
  • Patent number: 7913690
    Abstract: A method of calculating the flux of any gas (x) in a CBC circuit for a ventilated or a spontaneous breathing subject, for example said gas(x) being; a) an anesthetic such as but limited to; i)N2O; ii) sevoflurane; iii) isoflurane; iv) halothane; v) desflurame; or the like b) Oxygen; c) Carbon dioxide; or the like utilizing the following relationships; Flux of gas(x)=SGF (FSX?FEX) wherein SGF=Source of gas flow into the breathing circuit (CBC circuit) in liters/minute as read from the gas flow meter as set by the anesthesiologist; FSX=Fractional concentration of gas X in the source gas (which is set by the anesthesiologist); FEX=Fractional concentration of gas X in the end expired gas as determined by a portable gas analyzer, or the like.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: March 29, 2011
    Inventors: Joseph Fisher, David Preiss, Takafumi Azami, Alex Vesely, Eitan Prisman, Tehilla Adams
  • Publication number: 20090173348
    Abstract: An apparatus for inducing hypoxia in a subject is provided. The apparatus includes a breathing port, an inspiratory reservoir, means for introducing oxygen into the apparatus, means for controlling the flow rate of entry of oxygen into the apparatus at a rate below the subject's metabolic requirements, an expiratory reservoir having a vent, Sequential Gas Delivery means, and means for removing CO2 from the circuit.
    Type: Application
    Filed: February 24, 2006
    Publication date: July 9, 2009
    Inventors: Joseph A. Fisher, Alex Vesely, Hiroshi Sasano, Steve Iscoe, Ronald Somogyi, Eitan Prisman
  • Publication number: 20090120435
    Abstract: In a first aspect, the invention relates to an apparatus for inducing or maintaining a target end tidal concentration of a gas in a subject comprising a breathing circuit, a source of gas flow into the circuit, means for controlling the rate of the source of gas flow into the circuit and means for controlling the concentration of gases in the source gas flow independently from each other.
    Type: Application
    Filed: July 28, 2006
    Publication date: May 14, 2009
    Inventors: Marat Slessarev, Joe Fisher, George Volgyesi, Eitan Prisman, David Mikulus, Chris Hudson, Cliff Ansel
  • Publication number: 20070173729
    Abstract: A process for determining gas(x) consumption, wherein said gas(x) is selected from; a) an anesthetic such as but not limited to; i) N2O; ii) sevoflurane; iii) isoflurane; iv) halothane; v) desflurame; or the like b) Oxygen (O2).
    Type: Application
    Filed: February 18, 2004
    Publication date: July 26, 2007
    Inventors: Joseph Fisher, David Prebes, Takekumi Azami, Alex Vesely, Eitan Prisman, Steve Coe, Ron Somogyi
  • Publication number: 20070062534
    Abstract: A breathing circuit for use with a first gas set (FGS) and a second gas set (SGS), said circuit comprising means for keeping separate the FGS and SGS, and a means for sequentially delivering to a patient, first the FGS, and, on inspiration, when the patient inspires so as to deplete the supply of FGS into the circuit, subsequently delivers substantially SGS for the balance of inspiration.
    Type: Application
    Filed: February 18, 2004
    Publication date: March 22, 2007
    Inventors: Joseph Fisher, David Preiss, Takafumi Azami, Alex Vesely, Eitan Prisman, Steve Iscoe, Ron Somogyi, Dan Nayot, Tehilla Adams
  • Publication number: 20050217671
    Abstract: A method of calculating the flux of any gas (x) in a CBC circuit for a ventilated or a spontaneous breathing subject, for example said gas(x) being; a) an anesthetic such as but limited to; i)N2O; ii) sevoflurane; iii) isoflurane; iv) halothane; v) desflurame; or the like b) Oxygen; c) Carbon dioxide; or the like utilizing the following relationships; Flux of gas(x)=SGF (FSX?FEX) wherein SGF=Source of gas flow into the breathing circuit (CBC circuit) in liters/minute as read from the gas flow meter as set by the anesthesiologist; FSX=Fractional concentration of gas X in the source gas (which is set by the anesthesiologist); FEX=Fractional concentration of gas X in the end expired gas as determined by a portable gas analyzer, or the like.
    Type: Application
    Filed: March 21, 2003
    Publication date: October 6, 2005
    Inventors: Joseph Fisher, David Preiss, Takafumi Azami, Alex Vesely, Eitan Prisman, Tehilla Adams
  • Publication number: 20040060560
    Abstract: A method and device for effective delivery of a gas such as oxygen for inhalation is provided by sequentially diluting room air to the flow of gas during a respiratory cycle. A mask assembly is described that comprises an inspiratory and expiratory limb each containing a very low resistance one-way valve, and a sequential dilution conduit (leading from the atmosphere to the inspiratory limb) with a one-way valve that has a slightly positive cracking pressure. A gas reservoir is also attached to the inspiratory limb. During expiration, the reservoir is filled with oxygen, for example, flowing from the oxygen source. During inspiration, oxygen from the oxygen source and the reservoir are drawn preferentially. If the oxygen flow is equal to or greater than the minute ventilation of the subject, no atmospheric air is entrained into the mask assembly and the subject gets pure oxygen. If the minute ventilation (tidal volume) exceeds the oxygen flow, the reservoir is depleted.
    Type: Application
    Filed: September 27, 2002
    Publication date: April 1, 2004
    Applicant: SENSORMEDICS CORPORATION
    Inventors: Alex Stenzler, Joseph A. Fisher, Alex Vesely, Hiroshi Sasano, Ron B. Somogyi, George Volgyesi, Steve Iscoe, David Preiss, Eitan Prisman