Patents by Inventor Ekkehard Schuetz

Ekkehard Schuetz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PRECISE AND BIAS-FREE QUANTIFICATION OF CELL-FREE DNA
    Publication number: 20230121271
    Abstract: This invention provides a method of quantifying the amount of diagnostic cell-free DNA (cfDNA) in a cfDNA sample from a subject. Specifically, the method comprising quantifying the amount of a diagnostic cfDNA in a cfDNA sample from a subject using two or more PCR reactions, wherein the diagnostic cfDNA deviates from germline DNA of the subject for differentiating cfDNA between the shortening or lengthening of the individual's germline-originating cfDNA and the shortening or lengthening of the target diagnostic cfDNA from cells of interest that are present in the subject, such as cells from a tumor, a fetus (placenta) or a transplanted organ.
    Type: Application
    Filed: March 25, 2021
    Publication date: April 20, 2023
    Inventors: Ekkehard Schütz, Julia Beck
  • PROSTATE CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20230087365
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: August 15, 2022
    Publication date: March 23, 2023
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • BREAST CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20220333213
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: June 27, 2022
    Publication date: October 20, 2022
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • Method of determining a numeric index of tumor-associated copy number changes of circulating nucleic acids associated with prostate cancer
    Patent number: 11414706
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: August 16, 2022
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • Breast cancer associated circulating nucleic acid biomarkers
    Patent number: 11377695
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: July 5, 2022
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • DETECTION AND QUANTIFICATION OF DONOR CELL-FREE DNA IN THE CIRCULATION OF ORGAN TRANSPLANT RECIPIENTS
    Publication number: 20220025459
    Abstract: This invention provides methods, compositions, and kits relating to detecting donor cell-free DNA in the circulation of a transplant recipient for the early identification of transplant rejection or for detection of damage to transplant cells.
    Type: Application
    Filed: October 15, 2021
    Publication date: January 27, 2022
    Inventors: Ekkehard Schütz, Julia Beck
  • PROSTATE CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20190185928
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Inventors: Ekkehard SCHÜTZ, Julia BECK, Howard URNOVITZ
  • BREAST CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20190078165
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: August 13, 2018
    Publication date: March 14, 2019
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • Prostate Cancer Associated Circulating Nucleic Acid Biomarkers
    Publication number: 20180340233
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: May 21, 2018
    Publication date: November 29, 2018
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • Breast cancer associated circulating nucleic acid biomarkers
    Patent number: 10047397
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: August 14, 2018
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • Personalized biomarkers for cancer
    Patent number: 9909186
    Abstract: The invention provides methods and reagents for identifying personalized tumor biomarkers for a patient that has a solid tumor and methods of using such biomarkers to monitor patient responses to therapeutic treatments.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: March 6, 2018
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • PERSONALIZED BIOMARKERS FOR CANCER
    Publication number: 20160053328
    Abstract: The invention provides methods and reagents for identifying personalized tumor biomarkers for a patient that has a solid tumor and methods of using such biomarkers to monitor patient responses to therapeutic treatments.
    Type: Application
    Filed: December 13, 2013
    Publication date: February 25, 2016
    Applicant: CHRONIX BIOMEDICAL
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • PROSTATE CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20160002739
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: July 15, 2015
    Publication date: January 7, 2016
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • PROSTATE CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20130143214
    Abstract: The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: June 1, 2011
    Publication date: June 6, 2013
    Applicant: CHRONIX BIOMEDICAL
    Inventors: Ekkehard Schütz, Julia Beck, Howard Urnovitz
  • BREAST CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS
    Publication number: 20130116127
    Abstract: The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
    Type: Application
    Filed: April 18, 2011
    Publication date: May 9, 2013
    Applicant: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Julia Beck, Howard Urnovitz
  • Diagnostic detection of nucleic acids
    Publication number: 20100261164
    Abstract: This invention provides sensitive nucleic acid hybridization assay methods for the detection of target animal nucleic acids in a biological sample, such as acellular fluids. The methods are particularly useful in early diagnosis of animal diseases, particularly chronic illnesses.
    Type: Application
    Filed: May 14, 2007
    Publication date: October 14, 2010
    Applicant: Chronix Biomedical, Inc.
    Inventors: Ekkehard Schuetz, Howard B. Urnovitz
  • Detection of nucleic acids to assess risk for bovine spongiform encephalopathy
    Patent number: 7368243
    Abstract: The present invention provides a method of detecting abnormal serum nucleic acid profiles to assess the risk of a transmissible spongiform encephalopathy, e.g., BSE.
    Type: Grant
    Filed: July 8, 2005
    Date of Patent: May 6, 2008
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Leonid Iakoubov, Howard Urnovitz
  • Detection of nucleic acids to assess risk for Creutzfeldt-Jakob disease
    Publication number: 20060099621
    Abstract: The present invention provides a method of detecting abnormal circulating nucleic acid profiles to assess the risk of Creutzfeldt-Jakob Disease.
    Type: Application
    Filed: October 7, 2005
    Publication date: May 11, 2006
    Applicant: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Leonid Iakoubov, Howard Urnovitz
  • Detection of nucleic acids to assess risk for bovine spongiform encephalopathy
    Publication number: 20060068419
    Abstract: The present invention provides a method of detecting abnormal serum nucleic acid profiles to assess the risk of a transmissible spongiform encephalopathy, e.g., BSE.
    Type: Application
    Filed: July 8, 2005
    Publication date: March 30, 2006
    Applicant: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Leonid Iakoubov, Howard Urnovitz
  • Diagnostic detection of nucleic acids
    Publication number: 20040241712
    Abstract: This invention provides sensitive nucleic acid hybridization assay methods for the detection of target animal nucleic acids in a biological sample, such as acellular fluids. The methods are particularly useful in early diagnosis of animal diseases, particularly chronic illnesses.
    Type: Application
    Filed: January 21, 2004
    Publication date: December 2, 2004
    Applicant: Chronix Biomedical Inc.
    Inventors: Ekkehard Schuetz, Howard B. Urnovitz