Patents by Inventor Elena Viktorovna Sycheva

Elena Viktorovna Sycheva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9574216
    Abstract: The present invention describes a method for producing a useful metabolite using a bacterium of the family Enterobacteriaceae, particularly a bacterium belonging to the genus Escherichia, which has been modified to contain a gene(s) expression system including elements of the LysR-type protein-regulated transcriptional machinery modified in such a way that auto-inducible positive feedback regulation of the system is mediated by a coinducer. The method is suitable for producing branched-chain L-amino acids, particularly L-valine, L-isoleucine and L-leucine; and D-pantothenic acid.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: February 21, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventors: Elena Viktorovna Sycheva, Valery Vasilievich Samsonov, Ekaterina Alekseevna Savrasova, Natalia Sergeevna Eremina, Natalia Vladimirovna Geraskina, Natalia Viktorovna Stoynova
  • Patent number: 9279137
    Abstract: A mutant bacterial acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine is described. Also described is a method for producing branched-chain L-amino acids using a bacterium from the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by the use of the acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine. This acetolactate synthase contains a mutant small subunit encoded by the mutant ilvN gene.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: March 8, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Elena Viktorovna Sycheva, Vsevolod Aleksandrovich Serebryanyy, Tatyana Abramovna Yampolskaya, Ekaterina Sergeevna Preobrazhenskaya, Natalia Viktorovna Stoynova
  • Publication number: 20150017693
    Abstract: The present invention describes a method for producing a useful metabolite using a bacterium of the family Enterobacteriaceae, particularly a bacterium belonging to the genus Escherichia, which has been modified to contain a gene(s) expression system including elements of the LysR-type protein-regulated transcriptional machinery modified in such a way that auto-inducible positive feedback regulation of said system is mediated by a coinducer. The method is suitable for producing branched-chain L-amino acids, particularly L-valine, L-isoleucine and L-leucine; and D-pantothenic acid.
    Type: Application
    Filed: September 29, 2014
    Publication date: January 15, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Elena Viktorovna Sycheva, Valery Vasilievich Samsonov, Ekaterina Alekseevna Savrasova, Natalia Sergeevna Eremina, Natalia Vladimirovna Geraskina, Natalia Viktorovna Stoynova
  • Publication number: 20140335574
    Abstract: A mutant bacterial acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine is described. Also described is a method for producing branched-chain L-amino acids using a bacterium from the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by the use of the acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine. This acetolactate synthase contains a mutant small subunit encoded by the mutant ilvN gene.
    Type: Application
    Filed: July 17, 2014
    Publication date: November 13, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Elena Viktorovna Sycheva, Vsevolod Aleksandrovich Serebryanyy, Tatyana Abramovna Yampolskaya, Ekaterina Sergeevna Preobrazhenskaya, Natalia Viktorovna Stoynova
  • Publication number: 20090197309
    Abstract: A mutant bacterial acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine is described. Also described is a method for producing branched-chain L-amino acids using a bacterium from the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by the use of the acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine. This acetolactate synthase contains a mutant small subunit encoded by the mutant ilvN gene.
    Type: Application
    Filed: September 13, 2007
    Publication date: August 6, 2009
    Inventors: Elena Viktorovna Sycheva, Vsevolod Aleksandrovich Serebryanyy, Tatyana Abramovna Yampolskaya, Ekaterina Sergeevna Preobrazhenskaya, Natalia Viktorovna Stoynova
  • Publication number: 20040229320
    Abstract: The invention relates to a bacterium comprising an inactive mlc gene which produces an L-amino acid, such as L-threonine,
    Type: Application
    Filed: September 5, 2003
    Publication date: November 18, 2004
    Inventors: Natalia Viktorovna Stoynova, Elena Viktorovna Sycheva, Aleksandra Yurievna Skorokhodova, Yuri Ivanovich Kozlov
  • Publication number: 20040229321
    Abstract: A process for producing an L-amino acid, such as L-isoleucine, L-histidine, L-threonine and L-tryptophan, using bacterium belonging to the genus Escherichia is provided which comprises cultivating the L-amino acid-producing bacterium in a culture medium and collecting the L-amino acid from the culture medium, wherein the culture medium contains a mixture of glucose and pentose sugars, such as arabinose and xylose.
    Type: Application
    Filed: February 25, 2004
    Publication date: November 18, 2004
    Inventors: Ekaterina Alekseevna Savrasova, Elena Viktorovna Sycheva, Tatyana Anatolievna Michurina, Yuri Ivanovich Kozlov