Patents by Inventor Elfatih Elzein

Elfatih Elzein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl alkyl piperazine derivatives
    Publication number: 20040192702
    Abstract: Novel compounds of the general formula: 1
    Type: Application
    Filed: March 31, 2004
    Publication date: September 30, 2004
    Inventors: Jeff Zablocki, Prabha Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle
  • Substituted heterocyclic compounds
    Publication number: 20040186109
    Abstract: Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes.
    Type: Application
    Filed: January 16, 2004
    Publication date: September 23, 2004
    Inventors: Robert Jiang, Tim Marquart, Jeff Zablocki, Elfatih Elzein, Venkata Palle, Prabha Ibrahim
  • Substituted heterocyclic compounds
    Publication number: 20040176383
    Abstract: Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes, and for increasing HDL plasma levels in mammals.
    Type: Application
    Filed: January 16, 2004
    Publication date: September 9, 2004
    Inventors: Prabha Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle, Jeff Zablocki, Kenneth S. Rehder
  • A2B adenosine receptor antagonists
    Publication number: 20040176399
    Abstract: Disclosed are processes for the synthesis of novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.
    Type: Application
    Filed: November 21, 2003
    Publication date: September 9, 2004
    Inventors: Elfatih Elzein, Rao Kalla, Tim Marquart, Jeff Zablocki, Xiaofen Li
  • Substituted heterocyclic compounds
    Publication number: 20040152890
    Abstract: Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes.
    Type: Application
    Filed: December 5, 2003
    Publication date: August 5, 2004
    Inventors: Elfatih Elzein, Dmitry Koltun, Jeff Zablocki
  • Adenosine A3 receptor agonists
    Publication number: 20040116376
    Abstract: Disclosed are novel compounds that are A3 adenosine receptor agonists, useful for treating various disease states, including cancer, cardiac ischemia, leukopenia, and neutropennia.
    Type: Application
    Filed: November 25, 2003
    Publication date: June 17, 2004
    Inventors: Elfatih Elzein, Venkata Palle, Vaibhav Varkhedkar, Jeff Zablocki
  • Partial and full agonists of A1 adenosine receptors
    Publication number: 20040043960
    Abstract: Disclosed are novel compounds that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular the supraventricular tachycardias, emesis, angina, myocardial infarction and hyperlipidemia.
    Type: Application
    Filed: August 15, 2003
    Publication date: March 4, 2004
    Inventors: Jeff Zablocki, Venkata Palle, Elfatih Elzein, Xiaofen Li
  • Heteroaryl alkyl piperazine derivatives as fatty acid oxidation inhibitors
    Publication number: 20040029889
    Abstract: Novel compounds of the general formula (I): and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.
    Type: Application
    Filed: July 14, 2003
    Publication date: February 12, 2004
    Inventors: Jeff A Zablocki, Prabha N Ibrahim, Kevin Shunk, Elfatih Elzein, Venkata P Palle
  • Substituted piperazine compounds
    Patent number: 6677343
    Abstract: Novel compounds of the general formula: and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: January 13, 2004
    Assignee: CV Therapeutics, Inc.
    Inventors: Brent K. Blackburn, Jeff Zablocki, Elfatih Elzein, Grigory Nudelman
  • Substituted piperazine compounds
    Patent number: 6677336
    Abstract: Novel compounds of the general formula: and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: January 13, 2004
    Assignee: CV Therapeutics, Inc.
    Inventors: Jeff Zablocki, Elfatih Elzein, Grigory Nudelman, Tim Marquart, Brent K. Blackburn, Venkata P. Palle
  • Partial and full agonists of A1 adenosine receptors
    Publication number: 20030232783
    Abstract: Disclosed are novel compounds that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular tachycardia and atrial flutter, angina, myocardial infarction and hyperlipidemia.
    Type: Application
    Filed: February 18, 2003
    Publication date: December 18, 2003
    Inventors: Prabha Ibrahim, Elfatih Elzein, Kevin Shenk, Robert Jiang, Jeff Zablocki, Xiaofen Li, Christopher Morrison, Thao Perry, Dengming Xiao
  • A2B adenosine receptor antagonists
    Publication number: 20030229106
    Abstract: Disclosed are novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.
    Type: Application
    Filed: May 6, 2003
    Publication date: December 11, 2003
    Inventors: Rao Kalla, Thao Perry, Elfatih Elzein, Vaibhav Varkhedkar, Xiaofen Li, Prabha Ibrahim, Venkata Palle, Dengming Xiao, Jeff Zablocki
  • Heteroaryl alkyl piperazine derivatives
    Publication number: 20030216409
    Abstract: Novel compounds of the general formula: 1
    Type: Application
    Filed: December 5, 2002
    Publication date: November 20, 2003
    Inventors: Jeff Zablocki, Prabha Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle
  • Substituted heterocyclic compounds
    Publication number: 20030181352
    Abstract: Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes, and for increasing HDL plasma levels in mammals.
    Type: Application
    Filed: July 18, 2002
    Publication date: September 25, 2003
    Inventors: Prabha Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle, Jeff Zablocki, Kenneth Rehder
  • Aralkyl substituted piperazine compounds
    Publication number: 20030176440
    Abstract: Novel compounds of the general formula: 1
    Type: Application
    Filed: February 11, 2003
    Publication date: September 18, 2003
    Applicant: CV Therapeutics, Inc.
    Inventors: Jeff Zablocki, Elfatih Elzein, Brent K. Blackburn, Tim Marquart, Prabha N. Ibrahim, Venkata P. Palle
  • Substituted heterocyclic compounds
    Publication number: 20030176447
    Abstract: Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes, and for increasing HDL plasma levels in mammals.
    Type: Application
    Filed: January 17, 2003
    Publication date: September 18, 2003
    Inventors: Prabha Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle, Jeff Zablocki, Kenneth S. Rehder
  • A2B adenosine receptor antagonists
    Publication number: 20030139428
    Abstract: Disclosed are novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.
    Type: Application
    Filed: November 8, 2002
    Publication date: July 24, 2003
    Inventors: Rao Kalla, Thao Perry, Elfatih Elzein, Vaibhav Varkhedkar, Xiaofen Li, Prabha Ibrahim, Venkata Palle, Dengming Xiao, Jeff Zablocki
  • Heteroaryl alkyl piperazine derivatives
    Patent number: 6573264
    Abstract: Novel compounds of the general formula: and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: June 3, 2003
    Assignee: CV Therapeutics, Inc.
    Inventors: Jeff Zablocki, Prabha N. Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle
  • Adenosine receptor A3 agonists
    Publication number: 20030078232
    Abstract: Disclosed are novel compounds that are A3 adenosine receptor agonists, useful for treating various disease states, including cancer, cardiac ischemia, leukopenia, and neutropennia.
    Type: Application
    Filed: August 5, 2002
    Publication date: April 24, 2003
    Inventors: Elfatih Elzein, Venkata Palle, Vaibhav Varkhedkar, Jeff Zablocki
  • Aralkyl substituted piperazine compounds
    Patent number: 6552023
    Abstract: Novel compounds of the general formula: and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: April 22, 2003
    Assignee: CV Therapeutics, Inc.
    Inventors: Jeff Zablocki, Elfatih Elzein, Brent K. Blackburn, Tim Marquart, Prabha N. Ibrahim, Venkata P. Palle