Abstract: A device includes a medusa wire group with at least three separate wires slidably received in a vascular catheter. The multiple wires of the medusa wire group maximize the chances of at least one wire entering a target branch vessel during an attempt to achieve access. Entry into the branch vessel may then be gained by advancing the vascular catheter over the at least one wire that successfully entered the branch passageway.

Abstract: A method of making a contoured internal limb including providing a flattened tubular segment of graft material, and a prosthesis including the contoured internal limb. The tubular segment includes a left lateral edge, a right lateral edge, a first length extending from the left lateral edge to the right lateral edge, and a second length extending from a proximal end to a distal end of the tubular segment. The method also includes contouring a proximal portion, a middle portion, and a distal portion of the contoured internal limb from the tubular segment. The method also includes closing a right lateral edge of the proximal portion and a right lateral edge of a first section of the middle portion. The method further includes removing the proximal, middle and distal portions of the contoured internal limb from the tubular segment and maintaining a second section of the middle portion as circumferentially continuous.

Abstract: A bifurcated endovascular prosthesis that includes a tubular main body having a diameter, a proximal end, a distal end, an internal lumen extending from the proximal end to the distal end, an anterior side, and a posterior side. The anterior and posterior sides are opposite each other circumferentially around the internal lumen. The prosthesis also includes a first limb that extends from the distal end of the tubular main body along the anterior side of the main body. The first limb has a diameter less than the diameter of the tubular main body and having a proximal end and a distal end. The prosthesis also includes a fenestration adjacent to the proximal end of the first limb. The fenestration extends from the proximal end of the first limb to the posterior side of the tubular main body. The prosthesis also includes a second limb that extends within the internal lumen from the fenestration toward the proximal end of the tubular main body.

Abstract: A device includes a medusa wire group with at least three separate wires slidably received in a vascular catheter. The multiple wires of the medusa wire group maximize the chances of at least one wire entering a target branch vessel during an attempt to achieve access. Entry into the branch vessel may then be gained by advancing the vascular catheter over the at least one wire that successfully entered the branch passageway.

Abstract: The disclosure is directed to a targeting guidewire. The guidewire includes a distal portion including four portions and three transition zones between the adjacent portions. A first and a third portions have a smaller stiffness than a second and a fourth portions. The first and the third portions may also have a smaller overall outer diameters than the second and the fourth portions. The three transition zones comprises marking elements so as to delineate their locations.

Abstract: An intraluminal scoring system for expanding an opening within an intraluminal passage includes a balloon catheter which is positioned alongside plaque lining a wall of the intraluminal passage. A wire is positioned between the balloon and the plaque so that the inflation of the balloon restricts the wire between the balloon and the plaque. After the balloon is inflated, a mechanical vibration is induced in the proximal end of the wire by a lithotripter actuator. The vibration travels through the wire to the distal portion, causing the wire to impact the plaque lining the wall of the passage causing scoring, compression, or fragmentation of the plaque.

Abstract: Medical devices and methods of using medical devices are described herein. More particularly, the disclosure relates to introducers suitable for providing access to a body vessel and methods of using introducers. An example introducer comprises a sheath and a dilator moveably disposed within the sheath. The distal end of the dilator has a closed configuration and an open configuration and movement between the open and closed configurations can be accomplished by applying a proximally-directed force on the sheath such that the sheath moves in a proximal direction relative to the dilator.

Abstract: A stent delivery balloon catheter assembly includes a catheter that defines exactly one or two lumens, which includes an inflation lumen that extends from an inflation port at a proximal end to open through a distal end of the catheter. The catheter defines a wire guide channel that terminates at a wire guide exit located a distance from the distal end of the catheter. A balloon with a closed distal end is attached to the catheter distally of the wire guide exit, and extends distally beyond the distal end of the catheter. The balloon is in fluid communication with the inflation lumen. A column strength stiffener has a proximal end attached to the catheter distally of the wire guide exit, and has a balloon support segment extending distally away from the distal end of the catheter within the balloon.

Abstract: A system for providing lumen support and dilation includes a balloon catheter having an inner balloon and an outer mesh bonded to the shaft, with the mesh surrounding the inner balloon and defining an intermediate space therebetween. The mesh may have holes formed in an outer wall, with the inner balloon being free from holes. The shaft includes a delivery lumen in communication with the intermediate space. Daughter balloons are deliverable into the intermediate space through the delivery lumen and into engagement with holes formed in the mesh, where the daughter balloons are inflated and retained by the holes of the mesh. The catheter may include one or more preloaded wires extending through the delivery lumen and into the intermediate space and through the holes, such that the daughter balloons are deliverable over the wires into the corresponding hole.

Abstract: A system for providing dilation and support to a body vessel includes a shaft having two compliant balloons attached to the shaft and spaced apart longitudinally from each and defining a longitudinal intermediate space between them. The shaft includes an inflation lumen for inflating the balloons and a delivery lumen for delivering secondary balloons into the intermediate space. The shaft includes side-ports that provide communication from the delivery lumen. Secondary balloons are deliverable over wires that extend through the delivery lumen and out of the side-ports, with the secondary balloons delivered through the side ports and to a desired location and inflated in the intermediate space or adjacent the intermediate space, such as to branch vessels. The compliant balloons are inflatable toward each other to take up the intermediate and conform to the shape of the body vessel and the secondary balloons.

Abstract: A system for providing lumen support and dilation includes a balloon catheter having an inner balloon and an outer balloon bonded to the shaft, with the outer balloon subsuming the inner balloon and defining an intermediate space therebetween. The outer balloon may have holes formed in an outer wall, with the inner balloon being free from holes. The shaft includes a delivery lumen in communication with the intermediate space. Daughter balloons are deliverable into the intermediate space through the delivery lumen and into engagement with holes formed in the outer balloon, where the daughter balloons are inflated and retained by the holes of the outer balloon. The catheter may include one or more preloaded wires extending through the delivery lumen and into the intermediate space and through the holes, such that the daughter balloons are deliverable over the wires into the corresponding hole.

Abstract: A prosthesis may include a tubular frame comprising rings which are concentric along an axis of the tubular frame. The rings may have a serpentine shape with apexes in a longitudinal direction such that the rings are configured to move between a compressed configuration and an expanded configuration. A first ring of the rings can include a first apex that includes a first anchoring member extending radially outward and a first crossbar extending radially inward. The first ring can further include a second apex that neighbors the first apex. The first crossbar can extend toward the second apex and extend radially inward further than the second apex. When in the compressed configuration, the first crossbar can engage the second apex such that the first anchoring member is moved radially inward.

Abstract: A bifurcated endovascular prosthesis that includes a tubular main body having a diameter, a proximal end, a distal end, an internal lumen extending from the proximal end to the distal end, an anterior side, and a posterior side. The anterior and posterior sides are opposite each other circumferentially around the internal lumen. The prosthesis also includes a first limb that extends from the distal end of the tubular main body along the anterior side of the main body. The first limb has a diameter less than the diameter of the tubular main body and having a proximal end and a distal end. The prosthesis also includes a fenestration adjacent to the proximal end of the first limb. The fenestration extends from the proximal end of the first limb to the posterior side of the tubular main body. The prosthesis also includes a second limb that extends within the internal lumen from the fenestration toward the proximal end of the tubular main body.

Abstract: A method of making a contoured internal limb including providing a flattened tubular segment of graft material, and a prosthesis including the contoured internal limb. The tubular segment includes a left lateral edge, a right lateral edge, a first length extending from the left lateral edge to the right lateral edge, and a second length extending from a proximal end to a distal end of the tubular segment. The method also includes contouring a proximal portion, a middle portion, and a distal portion of the contoured internal limb from the tubular segment. The method also includes closing a right lateral edge of the proximal portion and a right lateral edge of a first section of the middle portion. The method further includes removing the proximal, middle and distal portions of the contoured internal limb from the tubular segment and maintaining a second section of the middle portion as circumferentially continuous.

Abstract: A tipless balloon catheter includes an elongate tubular body defining an inflation lumen and having proximal and distal ends. A balloon has a proximal neck mounted on the distal end of the elongate tubular body and a distal neck including a distal tip having a distal opening therethrough. The distal opening is in fluid communication with the inflation lumen and an interior of the balloon. A stiffening member extends between the distal end of the elongate tubular body and the distal neck of the balloon. The tipless balloon catheter has a wire guide path defined by the elongate tubular body, the interior of the balloon, and the distal opening.

Abstract: The invention relates to a low profile lumen free balloon catheter and a system for advancing the lumen free balloon from a build wire to a wire guide. The low profile balloon lacks an internal wire guide cannula between the catheter shaft and the soft tip. A releasable engagement is provided to connect/disconnect the build wire to/from the wire guide. A soft tip seals around the wire guide following advancement of the balloon catheter over the wire guide.

Abstract: The present embodiments describe an endograft having one or more apertures, and methods for constructing the same. In one example, an endograft comprises a proximal region having a proximal opening, and a distal region having first and second apertures separated by a partition. A body portion having a lumen is disposed between the proximal region and distal region, and has a central longitudinal axis. At least one of the first and second apertures is oriented oblique to the central longitudinal axis.

Abstract: The invention relates to a low profile lumen free balloon catheter and a system for advancing the lumen free balloon from a build wire to a wire guide. The low profile balloon lacks an internal wire guide cannula between the catheter shaft and the soft tip. A releasable engagement is provided to connect/disconnect the build wire to/from the wire guide. A soft tip seals around the wire guide following advancement of the balloon catheter over the wire guide.

Abstract: The present embodiments relate to an endovascular treatment system comprising a sheath having a sheath lumen and a sheath aperture located on a circumferential surface of the sheath, and an internal liner disposed at least partially within the sheath lumen. The internal liner comprises a liner aperture, a protrusion, and a liner lumen, and has a delivery state and an expanded state. In the expanded state, the protrusion extends out of the sheath lumen through the sheath aperture.

Abstract: Medical devices and methods of using medical devices are described herein. More particularly, the disclosure relates to introducers suitable for providing access to a body vessel and methods of using introducers. An example introducer comprises a sheath and a dilator moveably disposed within the sheath. The distal end of the dilator has a closed configuration and an open configuration and movement between the open and closed configurations can be accomplished by applying a proximally-directed force on the sheath such that the sheath moves in a proximal direction relative to the dilator.