Patents by Inventor Elizabeth Jane Lawlor

Elizabeth Jane Lawlor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090092592
    Abstract: The invention provides metS polypeptides and DNA (RNA) encoding metS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metS polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: October 19, 2007
    Publication date: April 9, 2009
    Applicant: REPLIDYNE, INC.
    Inventor: Elizabeth Jane Lawlor
  • Publication number: 20080124313
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Application
    Filed: December 10, 2007
    Publication date: May 29, 2008
    Applicant: REPLIDYNE, INC.
    Inventors: JOHN EDWARD HODGSON, ELIZABETH JANE LAWLOR
  • Patent number: 7361476
    Abstract: The invention provides metS polypeptides and DNA (RNA) encoding metS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: April 22, 2008
    Assignee: Replidyne, Inc.
    Inventor: Elizabeth Jane Lawlor
  • Patent number: 7335499
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: February 26, 2008
    Assignee: Replidyne, Inc.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Patent number: 7202071
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: April 10, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • Patent number: 6989255
    Abstract: The invention provides methionyl tRNA synthetase (tRS) enzymes from Staphylococcus aureus and methods of producing such tRS by recombinant techniques. Also provided are methods for utilizing tRS for the protection against infection, particularly bacterial infection, most particularly Staphylococcus aureus infection.
    Type: Grant
    Filed: April 29, 1999
    Date of Patent: January 24, 2006
    Assignee: Replidyne, Inc.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Patent number: 6903204
    Abstract: The invention provides Staphylococcus aureus methionyl tRNA synthetase polypeptides and DNA (RNA) encoding Staphylococcus aureus methionyl tRNA synthetase polypeptides and methods for producing such poypeptides by recombinant techniques. Also provided are methods for utilizing Staphylococcus aureus methionyl tRNA synthetase polypeptides for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: June 7, 2005
    Assignee: Replidyne, Inc.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Publication number: 20040014121
    Abstract: The invention provides metS polypeptides and DNA (RNA) encoding metS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metS polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: June 26, 2003
    Publication date: January 22, 2004
    Applicants: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Elizabeth Jane Lawlor
  • Publication number: 20030232373
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 14, 2003
    Publication date: December 18, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • Publication number: 20030171564
    Abstract: The invention provides argS polypeptides and DNA (RNA) encoding argS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing argS polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: June 1, 2002
    Publication date: September 11, 2003
    Applicant: SmithKline Beecham Corporation
    Inventor: Elizabeth Jane Lawlor
  • Patent number: 6416976
    Abstract: The invention provides trpS polypeptides and DNA (RNA) encoding trpS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing trpS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 22, 1999
    Date of Patent: July 9, 2002
    Inventors: Daniel Robert Gentry, Rebecca Claire Greenwood, Elizabeth Jane Lawlor
  • Publication number: 20020086024
    Abstract: The invention provides ratB polypeptides and DNA (RNA) encoding ratB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratB polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: January 30, 2001
    Publication date: July 4, 2002
    Inventors: Michael Terence Black, Elizabeth Jane Lawlor, Ceri John Lewis
  • Publication number: 20020082231
    Abstract: The invention provides ratC polypeptides and DNA (RNA) encoding ratC polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratC polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 21, 2001
    Publication date: June 27, 2002
    Inventors: Michael Terence Black, Elizabeth Jane Lawlor, Ceri John Lewis
  • Patent number: 6410286
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: February 4, 1998
    Date of Patent: June 25, 2002
    Assignee: SmithKline Beecham p.l.c..
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Patent number: 6410285
    Abstract: The invention provides alaS polypeptides and DNA (RNA) encoding alaS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing alaS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: June 25, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventor: Elizabeth Jane Lawlor
  • Publication number: 20020058799
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 2, 2001
    Publication date: May 16, 2002
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • Patent number: 6365159
    Abstract: spo-rel polypeptides and DNA (RNA) encoding such spo-rel and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spo-rel for the treatment of infection, particularly bacterial infections. Antagonists against such spo-rel and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spo-rel nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding the relA/spoT gene family and for detecting the polypeptide in a host.
    Type: Grant
    Filed: June 30, 1999
    Date of Patent: April 2, 2002
    Inventors: Martin Karl Russel Burnham, Daniel Robert Gentry, John Edward Hodgson, Elizabeth Jane Lawlor
  • Publication number: 20020034779
    Abstract: The invention provides argS polypeptides and DNA (RNA) encoding argS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing argS polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: February 27, 2001
    Publication date: March 21, 2002
    Applicant: SmithKline Beecham Corporation
    Inventor: Elizabeth Jane Lawlor
  • Patent number: 6346409
    Abstract: The invention provides trpS polypeptides and DNA (RNA) encoding trpS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing trpS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: February 12, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLC
    Inventors: Daniel Robert Gentry, Rebecca Claire Greenwood, Elizabeth Jane Lawlor
  • Pth
    Patent number: 6303771
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: October 16, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini