Patents by Inventor Ellen H. Fiss

Ellen H. Fiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for detection of
    Patent number: 11767567
    Abstract: Methods for the rapid detection of the presence or absence of Babesia in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Babesia and kits are provided that are designed for the detection of Babesia, including, but not limited to, the Babesia species of B. microti, B. divergens, B. duncani, and B. venatorum. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of Babesia.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: September 26, 2023
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Ellen H. Fiss, Jingtao Sun
  • Compositions and methods for detection of
    Patent number: 11718883
    Abstract: Methods for the rapid detection of the presence or absence of Babesia in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Babesia and kits are provided that are designed for the detection of Babesia, including, but not limited to, the Babesia species of B. microti, B. divergens, B. duncani, and B. venatorum. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of Babesia.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: August 8, 2023
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Ellen H. Fiss, Jingtao Sun
  • COMPOSITIONS AND METHODS FOR DETECTION OF CANDIDA AURIS
    Publication number: 20230193405
    Abstract: Methods for the rapid detection of the presence or absence of Candida auris (CA) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the CA 5.8 s/ITS2 rRNA gene, along with kits are provided that are designed for the detection of CA.
    Type: Application
    Filed: January 12, 2023
    Publication date: June 22, 2023
    Inventors: Ellen H. FISS HOBART, Jody Harris, Andrew T. Hill, Jingtao Sun, Natacha Sorenson, Jeffrey Alexander, Arrash Moghaddasi, Erin Gick, Stephen McCune
  • COMPOSITIONS AND METHODS FOR DETECTING METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS
    Publication number: 20230056677
    Abstract: Methods for the rapid detection of the presence or absence of mecA- and/or mecC-containing Staphylococcus aureus (mecA/mecC-MRSA) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the genes for mecA-MRSA and mecC-5 MRSA, along with kits are provided that are designed for the detection of mecA/mecC-MRSA.
    Type: Application
    Filed: December 22, 2020
    Publication date: February 23, 2023
    Inventors: Ellen H. Fiss Hobart, Jingtao Sun
  • COMPOSITIONS AND METHODS FOR DETECTION OF NEISSERIA GONORROHEAE
    Publication number: 20220220539
    Abstract: Methods for the rapid detection of the presence or absence of NG Pilin Inverting protein (PivNg) gene in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the NG PivNg genes, along with kits are provided that are designed for the detection of Neisseria gonorrhoeae (NG).
    Type: Application
    Filed: May 5, 2020
    Publication date: July 14, 2022
    Inventors: Ellen H. Fiss Hobart, Jingtao Sun
  • COMPOSITIONS AND METHODS FOR DETECTION OF BACTERIA AND FUNGI ASSOCIATED WITH BACTERIAL AND CANDIDA VAGINOSIS
    Publication number: 20220205020
    Abstract: Methods for the rapid detection of the presence or absence of a plurality of Bacterial Vaginosis-related (BV-related) bacteria and/or vulvovaginal candidiasis (VVC)-associated Candida in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting specific genes and kits are provided that are designed for the detection of BV-related bacteria and VVC-associated Candida.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 30, 2022
    Inventors: Ellen H. Fiss Hobart, Claudia Litterst, Sharon Ho-Chen Chiu, Nancy Patten, Ha Bich Tran, Julie Tsai, Rui Zhang
  • COMPOSITIONS AND METHODS FOR DETECTION OF CANDIDA AURIS
    Publication number: 20220017973
    Abstract: Methods for the rapid detection of the presence or absence of Candida auris (CA) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the CA 5.8s/ITS2 rRNA gene, along with kits are provided that are designed for the detection of CA.
    Type: Application
    Filed: December 3, 2019
    Publication date: January 20, 2022
    Inventors: Ellen H. FISS HOBART, Jody Harris, Andrew T. Hill, Jingtao Sun
  • Compositions and methods for detection of zika virus
    Patent number: 11155886
    Abstract: Methods for the rapid detection of the presence or absence of Zika virus in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Zika virus and kits are provided that are designed for the detection of Zika virus.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: October 26, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Slav Dugenny, Ellen H Fiss, Jeffery Fong, Marintha Heil, Eugene Spier, Jingtao Sun
  • Non-replicative transduction particles and transduction particle-based reporter systems
    Patent number: 11008602
    Abstract: Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: May 18, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Slav Dugenny, Ellen H Fiss, Marc Rehfuss
  • COMPOSITIONS AND METHODS FOR DETECTION OF BABESIA
    Publication number: 20200399716
    Abstract: Methods for the rapid detection of the presence or absence of Babesia in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Babesia and kits are provided that are designed for the detection of Babesia, including, but not limited to, the Babesia species of B. microti, B. divergens, B. duncani, and B. venatorum. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of Babesia.
    Type: Application
    Filed: July 13, 2020
    Publication date: December 24, 2020
    Inventors: Ellen H. Fiss, Jingtao Sun
  • COMPOSITIONS AND METHODS FOR DETECTION OF BABESIA
    Publication number: 20200399715
    Abstract: Methods for the rapid detection of the presence or absence of Babesia in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Babesia and kits are provided that are designed for the detection of Babesia, including, but not limited to, the Babesia species of B. microti, B. divergens, B. duncani, and B. venatorum. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of Babesia.
    Type: Application
    Filed: July 13, 2020
    Publication date: December 24, 2020
    Inventors: Ellen H. Fiss, Jingtao Sun
  • Compositions and methods for detection of
    Patent number: 10760137
    Abstract: Methods for the rapid detection of the presence or absence of Babesia in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Babesia and kits are provided that are designed for the detection of Babesia, including, but not limited to, the Babesia species of B. microti, B. divergens, B. duncani, and B. venatorum. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of Babesia.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: September 1, 2020
    Inventors: Ellen H. Fiss, Jingtao Sun
  • COMPOSITIONS AND METHODS FOR DETECTION OF ZIKA VIRUS
    Publication number: 20200232051
    Abstract: Methods for the rapid detection of the presence or absence of Zika virus in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Zika virus and kits are provided that are designed for the detection of Zika virus.
    Type: Application
    Filed: April 6, 2020
    Publication date: July 23, 2020
    Inventors: Slav Dugenny, Ellen H Fiss, Jeffery Fong, Marintha Heil, Eugene Spier, Jingtao Sun
  • Oligonucleotide inhibitor of DNA polymerases
    Patent number: 10683540
    Abstract: The invention comprises a reversible oligonucleotide inhibitor of nucleic acid polymerases. Methods of designing said inhibitors and using said inhibitors in amplification and detection of nucleic acid, particularly detection of RNA by RT-PCR are also disclosed.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: June 16, 2020
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Ellen H. Fiss, Joseph San Filippo
  • Compositions and methods for detection of Zika virus
    Patent number: 10655190
    Abstract: Methods for the rapid detection of the presence or absence of Zika virus in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Zika virus and kits are provided that are designed for the detection of Zika virus.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: May 19, 2020
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Slav Dugenny, Ellen H. Fiss, Jeffery Fong, Marintha Heil, Eugene Spier, Jingtao Sun
  • Oligonucleotides for controlling amplification of nucleic acids
    Patent number: 10358675
    Abstract: Methods and oligonucleotides are provided for detecting an internal control nucleic acid for qualitative and/or quantitative purposes.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: July 23, 2019
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Ellen H. Fiss, Nicolas Newton
  • NON-REPLICATIVE TRANSDUCTION PARTICLES AND TRANSDUCTION PARTICLE-BASED REPORTER SYSTEMS
    Publication number: 20190185948
    Abstract: Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 20, 2019
    Inventors: Slav Dugenny, Ellen H. Fiss, Marc Rehfuss
  • COMPOSITIONS AND METHODS FOR DETECTION OF BABESIA
    Publication number: 20190024189
    Abstract: Methods for the rapid detection of the presence or absence of Babesia in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting Babesia and kits are provided that are designed for the detection of Babesia, including, but not limited to, the Babesia species of B. microti, B. divergens, B. duncani, and B. venatorum. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of Babesia.
    Type: Application
    Filed: July 10, 2018
    Publication date: January 24, 2019
    Inventors: Ellen H. Fiss, Jingtao Sun
  • OLIGONUCLEOTIDES FOR CONTROLLING AMPLIFICATION OF NUCLEIC ACIDS
    Publication number: 20180327840
    Abstract: Methods and oligonucleotides are provided for detecting an internal control nucleic acid for qualitative and/or quantitative purposes.
    Type: Application
    Filed: July 24, 2018
    Publication date: November 15, 2018
    Inventors: Ellen H. Fiss, Nicolas Newton
  • OLIGONUCLEOTIDE INHIBITOR OF DNA POLYMERASES
    Publication number: 20180291429
    Abstract: The invention comprises a reversible oligonucleotide inhibitor of nucleic acid polymerases. Methods of designing said inhibitors and using said inhibitors in amplification and detection of nucleic acid, particularly detection of RNA by RT-PCR are also disclosed.
    Type: Application
    Filed: June 19, 2018
    Publication date: October 11, 2018
    Inventors: Ellen H. Fiss, Joseph San Filippo