Patents by Inventor Eloisa Lopez-Calle

Eloisa Lopez-Calle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Iridium-based complexes for ECL
    Patent number: 8772486
    Abstract: Novel iridium-based Ir (III) luminescent complexes, conjugates comprising these complexes as a label and their application, for example in electrochemiluminescence based detection of an analyte.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: July 8, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Robert Cysewski, Luisa de Cola, Jesus Miguel Fernandez Hernandez, Hans-Peter Josel, Eloisa Lopez-Calle, Toralf Zarnt
  • NEW IRIDIUM-BASED COMPLEXES FOR ECL
    Publication number: 20130323857
    Abstract: Novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, for example in electrochemiluminescence based detection of an analyte.
    Type: Application
    Filed: August 7, 2013
    Publication date: December 5, 2013
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Robert Cysewski, Luisa de Cola, Jesus Miguel Fernandez Hernandez, Hans-Peter Josel, Eloisa Lopez-Calle, Toralf Zarnt
  • NEW IRIDIUM-BASED COMPLEXES FOR ECL
    Publication number: 20130323719
    Abstract: Novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, for example in the electrochemiluminescence based detection of an analyte.
    Type: Application
    Filed: August 7, 2013
    Publication date: December 5, 2013
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Robert Cysewski, Luisa de Cola, Jesus Miguel Fernandez Hernandez, Hans-Peter Josel, Eloisa Lopez-Calle, Toralf Zarnt
  • TEST APPARATUS, PRODUCTION METHOD THEREFOR AND TEST METHOD
    Publication number: 20090061460
    Abstract: Test apparatus for detecting an analyte (A) contained in a sample liquid, comprising a dry porous carrier (10), on which a selective binder (12), capable of selectively binding the analyte (A) after the carrier (10) is wetted with the sample fluid, is arranged in a reaction zone (20), wherein furthermore arranged in the reaction zone (20) are: a complex, formed by a biomarker (B) and the first complexed reporter partner of a pair of reporters, interacting to produce an optically detectable signal, of reporter enzyme (E) and reporter substrate (S), and the second, free reporter partner of the pair of reporters, wherein the biomarker (B), in terms of the selectivity of the binding capacity of the selective binder (12), is equivalent to the analyte (A) and competitive therewith and wherein binding of the selective binder (12) to the complexed biomarker (B) impedes the interaction between the complexed and the free reporter partners.
    Type: Application
    Filed: August 28, 2008
    Publication date: March 5, 2009
    Applicant: ANALYTICON BIOTECHNOLOGIES AG
    Inventors: Eloisa Lopez-Calle, Juergen Oberstrass, Werner Siekmann
  • Method for the detection of enzyme-catalyzed cleavage reactions by fluorescence spectroscopy
    Patent number: 7425425
    Abstract: A method involves the detection of enzyme-catalyzed cleavage reactions using modular chemical compounds as substrates for the enzymes involved, and detection is effected by use of molecular-weight-sensitive methods.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: September 16, 2008
    Assignee: Evotec Oai AG
    Inventors: Eloisa Lopez-Calle, Joachim Fries, Joern Jungmann
  • Methods and means for the detection of enzyme-catalyzed cleavage and linking reactions
    Publication number: 20070122863
    Abstract: The invention relates to methods and means for the detection of enzyme-catalyzed cleavage and linking reactions. Modular chemical compounds which serve as substrates for the enzymes involved are provided. The detection of the reaction products is effected by means of molecular-weight-sensitive methods.
    Type: Application
    Filed: May 12, 2006
    Publication date: May 31, 2007
    Inventors: Eloisa Lopez-Calle, Joachim Fries, Joern Jungmann
  • OXAZINE DERIVATIVES
    Publication number: 20060240455
    Abstract: Oxazine derivatives with which a broad spectrum of material to be studied can be labelled and identified by means of fluorescence techniques are described.
    Type: Application
    Filed: April 20, 2006
    Publication date: October 26, 2006
    Inventors: Joachim Fries, Eloisa Lopez-Calle, Karl-Heinz Drexhage
  • Oxazine derivatives
    Patent number: 7101999
    Abstract: The invention relates to oxazine derivatives by means of which a broad spectrum of material to be examined can be marked and identified using fluorescence techniques.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: September 5, 2006
    Assignee: Evotec AG
    Inventors: Joachim Fries, Eloisa Lopez-Calle, Karl-Heinz Drexhage
  • Methods and means for detecting enzymatic cleavage and linkage reactions
    Publication number: 20040241782
    Abstract: The invention relates to methods and means for the detection of enzyme-catalyzed cleavage and linking reactions. Modular chemical compounds which serve as substrates for the enzymes involved are provided. The detection of the reaction products is effected by means of molecular-weight-sensitive methods.
    Type: Application
    Filed: January 7, 2004
    Publication date: December 2, 2004
    Inventors: Eloisa Lopez-Calle, Joachim Fries, Joern Jungmann
  • Oxazine derivatives
    Publication number: 20040029837
    Abstract: The invention relates to oxazine derivatives by means of which a broad spectrum of material to be examined can be marked and identified using fluorescence techniques.
    Type: Application
    Filed: July 14, 2003
    Publication date: February 12, 2004
    Inventors: Joachim Fries, Eloisa Lopez-Calle, Karl-Heinz Drexhage