Patents by Inventor Emerson W. Chan

Emerson W. Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the detection of HTLV-II antibodies employing novel HTLV-II NRA envelope peptides
    Patent number: 6406841
    Abstract: The present invention relates generally to a novel human T-cell lymphotropic, or leukemia, virus type II (HTLV-II) isolate designated NRA. HTLV-IINRA was originally isolated from a patient with atypical hairy cell leukemia. Preliminary restriction analysis of this isolate demonstrated that it differs genetically from the prototypical HTLV-II isolate Mo. HTLV-IINRA proviral molecular clones were obtained and the entire nucleotide sequence of the virus ascertained. The claimed invention is particularly directed toward the gp46 and p21e envelope proteins encoded by the env gene. Methods and kits for the detection of HTLV-II antibodies employing these envelope proteins are also described.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: June 18, 2002
    Assignee: Abbott Laboratories
    Inventors: Helen H. Lee, Priscilla A. Swanson, Kenneth B. Idler, Joseph D. Rosenblatt, Irvin S. Y. Chen, David W. Golde, Eugene Robertson, John E. Stephens, Emerson W. Chan, Mark H. Buytendorp, Joan E. Johnson, Cheryl T. Motley, Michelle Edwards, Cynthia Tate, Bryan Peterson, Peggy Guidinger
  • METHODS FOR THE DETECTION OF HTLV-II ANTIBODIES EMPLOYIING NOVEL HTLV-II nra ENVELOPE PEPTIDES
    Publication number: 20020042045
    Abstract: Compositions including lysates, DNA and amino acid sequences derived from HTLV-IINRA are provided. Assays for detecting HTLV infection that employ the disclosed HTLV-IINRA compositions are also provided. Kits for performing HTLV assays are further provided.
    Type: Application
    Filed: June 20, 1994
    Publication date: April 11, 2002
    Inventors: HELEN H. LEE, PRISCILLA A. SWANSON, KENNETH B. IDLER, JOSEPH D. ROSENBELT, RIVIN S. Y. CHEN, DAVID W. GOLDE, EUGENE ROBERTSON, JOHN E. STEPHENS, EMERSON W. CHAN, MARK H. BUYTENDORP, JOAN E. JOHNSON, CHERYL T. MOTLEY, MICHELLE EDWARDS, CYNTHIA TATE, BRYAN PETERSON, PEGGY GUIDINGER
  • Process for preparing an improved western blot immunoassay
    Patent number: 5356772
    Abstract: The present invention encompasses an improved immunoassay method which involves the simultaneous transfer of multiple antigens onto a single solid support. The antigens which may be utilized by this method may be either naturally or recombinantly produced and may be purified on a variety of electrophoresis gels. This method is particularly useful to provide an extremely sensitive multiple component assay using essentially pure antigenic polypeptides capable of detecting the presence or antibodies to HIV-1 or HIV-2 viruses in infected patients.
    Type: Grant
    Filed: December 5, 1990
    Date of Patent: October 18, 1994
    Assignee: Abbott Laboratories
    Inventors: Emerson W. Chan, William G. Robey, Werner Schulze
  • Multilayer solid phase immunoassay support and method of use
    Patent number: 5120662
    Abstract: An immunoassay which is capable of simultaneously detecting any desired number of antigens of one infectious agent, or combinations of antigens of several infectious agents, or any desired number of immunoglobulins of one infectious agent, or combinations of immunoglobulins of several infectious agents on a single solid support. A test sample is contacted with a solid support on which one or more antigens are immobilized as discrete test sites. Antigen-antibody complexes are formed and detected on the solid support.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: June 9, 1992
    Assignee: Abbott Laboratories
    Inventors: Emerson W. Chan, Werner Schulze, William G. Robey, Brian P. Braun, Cynthia K. Daluga, Andreas A. Kapsalis, Kevin M. Knigge, John E. Stephens, Joseph J. Stojak, II, David S. Vallaris, Benton A. Durley, deceased, James D. Defreese, Carl W. Merkh
  • Production of hepatitis A virus in vitro utilizing a persistently virus infected cell culture system
    Patent number: 4721675
    Abstract: The present invention relates to a method for producing human hepatitis A virus in vitro employing tissue culture techniques. In particular, the present invention relates to an in vitro tissue culture procedure utilizing a persistently infected cell line that produces high titers of hepatitis A virus. The hepatitis A virus thus produced is a source of hepatitis A virus antigens.
    Type: Grant
    Filed: February 4, 1985
    Date of Patent: January 26, 1988
    Assignee: Abbott Laboratories
    Inventors: Emerson W. Chan, Joel R. Mitchen