Patents by Inventor Emily Sheng-ming Shen

Emily Sheng-ming Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Finger-1 Peptide Analogs of the TGF-Beta Superfamily
    Publication number: 20100286071
    Abstract: Members of the TGF-? superfamily and peptide fragments based on member proteins are employed to purify solutions containing member proteins or as therapeutics.
    Type: Application
    Filed: June 17, 2010
    Publication date: November 11, 2010
    Applicant: Wyeth LLC
    Inventors: Zhijian Lu, Wei Liu, Jimin Zhang, Paul John Yaworsky, Stephane H. Olland, Christopher Todd Brown, Emily Sheng-ming Shen
  • GDF-9/BMP-15 modulators for the treatment of bone disorders
    Patent number: 7790161
    Abstract: The invention provides methods for treating or preventing bone degenerative disorders. The disorders treated or prevented include, for example, osteopenia, osteomalacia, osteoporosis, osteomyeloma, osteodystrophy, Paget's disease, osteogenesis imperfecta, and bone degenerative disorders associated with chronic renal disease, hyperparathyroidism, and long-term use of corticosteroids. The disclosed therapeutic methods include administering to a mammal an inhibitor of GDF-9 or BMP-15 in an amount effective to: (1) treat or prevent a bone degenerative disorder; (2) slow bone deterioration; (3) restore lost bone; (4) stimulate new bone formation; and/or (5) maintain bone mass and/or bone quality. The invention also provides methods for administering a GDF-9 agonist or a BMP-15 agonist to treat a bone disorder characterized by increased bone density or mass.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: September 7, 2010
    Assignee: Wyeth LLC
    Inventors: Emily Sheng-Ming Shen, Frederick J. Bex, Yogendra P. Kharode, Vargheese M. Chennathukuzhi, Murty V. Chengalvala, Ashok Bapat, Panayiotis E. Stevis, Gregory S. Kopf
  • Finger-1 peptide analogs of the TGF-? superfamily
    Patent number: 7754689
    Abstract: Members of the TGF-? superfamily and peptide fragments based on member proteins are employed to purify solutions containing member proteins or as therapeutics.
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: July 13, 2010
    Assignee: Wyeth LLC
    Inventors: Zhijian Lu, Wei Liu, Jimin Zhang, Paul John Yaworsky, Stephane H. Olland, Christopher Todd Brown, Emily Sheng-ming Shen
  • Use of proteins and peptides of the TGF-Beta superfamily for purification and therapeutic methods
    Publication number: 20080051340
    Abstract: Members of the TGF-? superfamily and peptide fragments based on member proteins are employed to purify solutions containing member proteins or as therapeutics.
    Type: Application
    Filed: June 1, 2007
    Publication date: February 28, 2008
    Applicant: Wyeth
    Inventors: Zhijian Lu, Wei Liu, Jimin Zhang, Paul Yaworsky, Stephane Olland, Christopher Brown, Emily Sheng-ming Shen