Patents by Inventor Emmanuel Jules Hanon

Emmanuel Jules Hanon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200360507
    Abstract: The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolisable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent.
    Type: Application
    Filed: December 20, 2019
    Publication date: November 19, 2020
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Emmanuel Jules HANON, Jean STEPHENNE
  • Patent number: 10555999
    Abstract: The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolisable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: February 11, 2020
    Assignee: GLAXOSMITHKLINE BIOLOGICASL SA
    Inventors: Emmanuel Jules Hanon, Jean Stephenne
  • Patent number: 10548969
    Abstract: The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 ?g HA or a low amount such as less than 15 ?g HA.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: February 4, 2020
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: William Ripley Ballou, Emmanuel Jules Hanon
  • Publication number: 20190054162
    Abstract: The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolisable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent.
    Type: Application
    Filed: March 14, 2018
    Publication date: February 21, 2019
    Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Emmanuel Jules HANON, Jean STEPHENNE
  • Publication number: 20180339037
    Abstract: The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 ?g HA or a low amount such as less than 15 ?g HA.
    Type: Application
    Filed: June 26, 2018
    Publication date: November 29, 2018
    Inventors: William Ripley Ballou, Emmanuel Jules Hanon
  • Patent number: 10016495
    Abstract: The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 ?g HA or a low amount such as less than 15 ?g HA.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: July 10, 2018
    Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: William Ripley Ballou, Emmanuel Jules Hanon
  • Patent number: 9943588
    Abstract: The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolisable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: April 17, 2018
    Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Emmanuel Jules Hanon, Jean Stephenne
  • Publication number: 20170246290
    Abstract: The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 ?g HA or a low amount such as less than 15 ?g HA.
    Type: Application
    Filed: March 1, 2017
    Publication date: August 31, 2017
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: William Ripley BALLOU, Emmanuel Jules HANON
  • Patent number: 9730999
    Abstract: The present invention relates to influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to multivalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from at least two influenza virus strains, at least one strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: August 15, 2017
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: Emmanuel Jules Hanon, Jean Stephenne
  • Patent number: 9700605
    Abstract: The present invention provides an immunogenic composition comprising an antigen or antigen composition and an adjuvant composition comprising an oil in water emulsion, wherein said oil in water emulsion comprises 0.5-10 mg metabolizable oil, 0.5-11 mg tocol and 0.1-4 mg emulsifying agent, per human dose.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: July 11, 2017
    Assignee: GlaxoSmithKline Biologicals S.A.
    Inventors: William Ripley Ballou, Jr., Emmanuel Jules Hanon
  • Patent number: 9597389
    Abstract: The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 ?g HA or a low amount such as less than 15 ?g HA.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: March 21, 2017
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: William Ripley Ballou, Emmanuel Jules Hanon
  • Patent number: 9452209
    Abstract: The present invention provides an immunogenic influenza composition in a dose volume suitable for human use, comprising an influenza virus antigen or antigenic preparation thereof and an adjuvant composition comprising an oil-in-water emulsion, wherein said oil-in-water emulsion comprises a metabolisable oil at a level of below 11 mg and an emulsifying agent at a level of below 5 mg and optionally a tocol or a sterol at a level of below 12 mg. Suitably the amount of influenza antigen per strain per dose is 15 ?g HA or a low amount such as less than 15 ?g HA.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: September 27, 2016
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: William Ripley Ballou, Emmanuel Jules Hanon
  • Publication number: 20160256537
    Abstract: The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolisable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent.
    Type: Application
    Filed: January 15, 2016
    Publication date: September 8, 2016
    Inventors: Emmanuel Jules HANON, Jean STEPHENNE
  • Patent number: 9278127
    Abstract: The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunizing against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolizable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: March 8, 2016
    Assignee: GLAXOSMITHKLINE BIOLOGICALS, SA
    Inventors: Emmanuel Jules Hanon, Jean Stephenne
  • Publication number: 20150359863
    Abstract: The present invention provides an immunogenic composition comprising an antigen or antigen composition and an adjuvant composition comprising an oil in water emulsion, wherein said oil in water emulsion comprises 0.5-10 mg metabolisable oil, 0.5-11 mg tocol and 0.1-4 mg emulsifying agent, per human dose.
    Type: Application
    Filed: January 9, 2015
    Publication date: December 17, 2015
    Inventors: William Ripley BALLOU, JR., Emmanuel Jules HANON
  • Publication number: 20140363474
    Abstract: The present invention relates to influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to multivalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from at least two influenza virus strains, at least one strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant.
    Type: Application
    Filed: August 21, 2014
    Publication date: December 11, 2014
    Inventors: Emmanuel Jules HANON, Jean STEPHENNE
  • Patent number: 8668904
    Abstract: The present invention relates to influenza vaccine formulations and accelerating primary vaccination regimes for immunizing against influenza disease, their use in medicine, in particular their use in promoting effective immune responses to various antigens, and to methods of preparation. In particular, the invention relates to two-doses accelerated pandemic or seasonal pandemic primary immunization regimes with influenza immunogenic compositions comprising an influenza virus or antigenic preparation thereof in combination with an oil-in-water emulsion adjuvant, and to accelerated immunization regimes.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: March 11, 2014
    Assignee: Glaxosmithkline Biologicals S.A.
    Inventor: Emmanuel Jules Hanon
  • Publication number: 20120164178
    Abstract: The present invention provides an immunogenic composition comprising a Streptococcus pneumoniae antigen and an adjuvant composition comprising an oil in water emulsion, wherein said oil in water emulsion comprises 0.5-10 mg metabolisable oil, 0.5-11 mg tocol and 0.1-4 mg emulsifying agent, per human dose.
    Type: Application
    Filed: April 16, 2009
    Publication date: June 28, 2012
    Inventors: William Ripley Ballou, JR., Emmanuel Jules Hanon
  • Publication number: 20110287054
    Abstract: The present invention relates to influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to multivalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from at least two influenza virus strains, at least one strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant.
    Type: Application
    Filed: April 28, 2011
    Publication date: November 24, 2011
    Inventors: Emmanuel Jules HANON, Jean Stephenne
  • Publication number: 20110243987
    Abstract: The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to monovalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from an influenza virus strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant comprising a metabolisable oil, a sterol and/or a tocopherol such as alpha tocopherol, and an emulsifying agent.
    Type: Application
    Filed: June 17, 2011
    Publication date: October 6, 2011
    Inventors: Emmanuel Jules Hanon, Jean Stephenne