Patents by Inventor Enrico G. Baggiolini

Enrico G. Baggiolini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediate racemates for the preparation of biotin and a process for their preparation
    Patent number: 4284557
    Abstract: A process is disclosed for producing d-biotin from L or DL-cystine ester via novel intermediates.
    Type: Grant
    Filed: May 15, 1980
    Date of Patent: August 18, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Enrico G. Baggiolini, Hsi L. Lee, Milan R. Uskokovic
  • Hexahydro thieno imadazole intermediates for the synthesis of biotin
    Patent number: 4247704
    Abstract: A process is disclosed for producing d-biotin from L or DL-cystine ester via novel intermediates.
    Type: Grant
    Filed: May 29, 1979
    Date of Patent: January 27, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Enrico G. Baggiolini, Hsi L. Lee, Milan R. Uskokovic
  • Isoxazolines and isoxazolidines
    Patent number: 4245104
    Abstract: A process is disclosed for producing d-biotin from L-cystine via novel intermediates.
    Type: Grant
    Filed: December 1, 1978
    Date of Patent: January 13, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Enrico G. Baggiolini, Hsi L. Lee, Milan R. Uskokovic
  • Vitamin D.sub.3 metabolite derivatives
    Patent number: 4225525
    Abstract: This disclosure relates to 3-hemisuccinate or 3-hemiglutarate derivatives of the biologically active metabolites of Vitamin D.sub.3 which possess Vitamin D activities and uses. The subject compounds also are useful as haptens which can be used to prepare immunogens which in turn elicit antibodies selective to said respective Vitamin D.sub.3 metabolites.
    Type: Grant
    Filed: February 8, 1979
    Date of Patent: September 30, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Enrico G. Baggiolini, Milan R. Uskokovic
  • Preparation of biotin
    Patent number: 4189586
    Abstract: A novel procedure for the preparation of biotin employing cysteine as the starting material is disclosed. This synthesis involves the formation of the thiophane ring by a 1,3-dipolar addition. By virtue of this process pure d-biotin can be obtained, thus obviating the need for chemical resolution. Novel intermediates are also disclosed.
    Type: Grant
    Filed: September 28, 1978
    Date of Patent: February 19, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Enrico G. Baggiolini, Hsi L. Lee, Milan R. Uskokovic
  • Biotin intermediates
    Patent number: 4130713
    Abstract: A novel procedure for the preparation of biotin employing cysteine as the starting material is disclosed. This synthesis involves the formation of the thiophane ring by a 1,3-dipolar addition. By virtue of this process pure d-biotin can be obtained, thus obviating the need for chemical resolution. Novel intermediates are also disclosed.
    Type: Grant
    Filed: August 5, 1977
    Date of Patent: December 19, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Enrico G. Baggiolini, Hsi L. Lee, Milan R. Uskokovic