Patents by Inventor Enrico MALITO

Enrico MALITO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250009874
    Abstract: Described are mutant, human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
    Type: Application
    Filed: April 30, 2024
    Publication date: January 9, 2025
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Enrico MALITO, Sumana CHANDRAMOULI, Andrea CARFI, Matthew BOTTOMLEY
  • Publication number: 20240383949
    Abstract: Described are mutant human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
    Type: Application
    Filed: February 7, 2024
    Publication date: November 21, 2024
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Enrico MALITO, Matthew James BOTTOMLEY, Andrea CARFI, Sumana CHANDRAMOULI, Kate LUISI
  • Publication number: 20240218026
    Abstract: Modified meningococcal fHbp polypeptides with increased stability.
    Type: Application
    Filed: February 13, 2024
    Publication date: July 4, 2024
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Matthew BOTTOMLEY, Enrico MALITO, Manuele MARTINELLI, Maria SCARSELLI
  • Patent number: 11932671
    Abstract: Modified meningococcal fHbp polypeptides with increased stability.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: March 19, 2024
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Matthew Bottomley, Enrico Malito, Manuele Martinelli, Maria Scarselli
  • Patent number: 11932669
    Abstract: Described are mutant human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: March 19, 2024
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Enrico Malito, Matthew James Bottomley, Andrea Carfi, Sumana Chandramouli, Kate Luisi
  • Publication number: 20230248820
    Abstract: Described are mutant, human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
    Type: Application
    Filed: April 18, 2018
    Publication date: August 10, 2023
    Inventors: Enrico Malito, Sumana Chandramouli, Andrea Carfi, Matthew Bottomley
  • Publication number: 20230234992
    Abstract: Betacoronavirus Spike proteins, or fragments thereof, including substitution mutations designed to increase stability, decrease the risk of antibody dependent enhancement, or both; and that are useful in, for example, immunogenic compositions.
    Type: Application
    Filed: June 4, 2021
    Publication date: July 27, 2023
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Marco BIANCUCCI, Joel David KARPIAK, Jason Paul LALIBERTE, Anna Ulrika LOWEGARD, Enrico MALITO, Newton Muchugu WAHOME
  • Publication number: 20210277067
    Abstract: Described are mutant human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
    Type: Application
    Filed: April 6, 2021
    Publication date: September 9, 2021
    Inventors: Enrico MALITO, Matthew James BOTTOMLEY, Andrea CARFI, Sumana CHANDRAMOULI, Kate LUISI
  • Publication number: 20210253647
    Abstract: Modified meningococcal fHbp polypeptides with increased stability.
    Type: Application
    Filed: April 30, 2021
    Publication date: August 19, 2021
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Matthew BOTTOMLEY, Enrico MALITO, Manuele MARTINELLI, Maria Scarselli
  • Patent number: 11021522
    Abstract: Modified meningococcal fHbp polypeptides with increased stability.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: June 1, 2021
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Matthew Bottomley, Enrico Malito, Manuele Martinelli, Maria Scarselli
  • Publication number: 20190315812
    Abstract: Modified meningococcal fHbp polypeptides with increased stability.
    Type: Application
    Filed: July 1, 2019
    Publication date: October 17, 2019
    Inventors: Matthew BOTTOMLEY, Enrico MALITO, Manuele MARTINELLI
  • Patent number: 10392424
    Abstract: Modified meningococcal fHbp polypeptides with increased stability.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: August 27, 2019
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Matthew Bottomley, Enrico Malito, Manuele Martinelli, Maria Scarselli
  • Publication number: 20170008933
    Abstract: Modified meningococcal fHbp polypeptides with increased stability.
    Type: Application
    Filed: February 27, 2015
    Publication date: January 12, 2017
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Matthew BOTTOMLEY, Enrico MALITO, Manuele MARTINELLI, Maria SCARSELLI