Abstract: A liquid level sensing and monitoring system for a medical fluid infusion system has an IV spike with a pressure sensor which contacts fluid in an infusion container such as an IV bag or bottle. When an adequate amount of fluid is in the container, the resulting pressure on the sensor is at a relatively high level; however, when the fluid reservoir is nearly depleted, the pressure on the sensor falls to a low level, thereby activating the sensor and associated control circuitry which operates an alarm or warning indicator. In lieu of the pressure sensor, the device may use a resistive or capacitive sensor. When the liquid level falls below the electrical sensor, its state changes, and the alarm circuitry is activated.