Patents by Inventor Eric Lingueglia

Eric Lingueglia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides which have analgesic effects and which inhibit ASIC channels
    Patent number: 8987207
    Abstract: Novel isolated peptides which induce analgesia and which inhibit ASIC channels (Acid Sensing Ion Channels), to the polynucleotides encoding these peptides, and also to the pharmaceutical compositions, host cells, and vectors comprising these peptides and the polynucleotides encoding these peptides. In particular, these peptides are isolated from the venom of the snake Dendroaspis polylepis. The present invention also relates to the use of these peptides as a diagnostic tool or as a medicament, particularly as an analgesic, or for identifying analgesic molecules or molecules which inhibit ASIC channels.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: March 24, 2015
    Assignee: Centre National de la Recherche Scientifique—CNRS
    Inventors: Éric Lingueglia, Sylvie Diochot, Anne Baron-Forster, Miguel Salinas, Michel Lazdunski
  • NOVEL PEPTIDES WHICH HAVE ANALGESIC EFFECTS AND WHICH INHIBIT ASIC CHANNELS
    Publication number: 20130196923
    Abstract: The present invention relates to novel isolated peptides which induce analgesia and which inhibit ASIC channels (Acid Sensing Ion Channels), to the polynucleotides encoding said peptides, and also to the pharmaceutical compositions, host cells and vectors comprising same. In particular, said peptides are isolated from the venom of the snake Dendroaspis polylepis. The present invention also relates to the use thereof as a diagnostic tool or as medicament, and in particular as an analgesic, or for identifying analgesic molecules or molecules which inhibit ASIC channels.
    Type: Application
    Filed: July 26, 2011
    Publication date: August 1, 2013
    Applicant: CENTRE NATIONAL DE LA RESERCHE SCIENTIFIQUE-CNRS
    Inventors: Eric Lingueglia, Sylvie Diochot, Anne Baron-Forster, Miguel Salinas, Michel Lazdunski
  • Method of treating pain or itching with APETx2 peptide toxin
    Patent number: 8357659
    Abstract: The invention relates to the use of the peptide toxin APETx2 that blocks the ASIC3 cationic channels and that is derived from the Anthopleura elegantissima sea anemone, and to the use of the analogs and derivatives thereof as a drug, particularly as an analgesic pain associated with the activation of ASIC3 (Acid Sensing Ion Channel 3) channels, in particular pain occurring upon an inflammation and potentially upon any painful situation associated with tissue acidosis (ischemiae, fractures, hematoma, oedema, phlyctena, local infections, tissue lesions, ocular wounds, tumours, etc.).
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: January 22, 2013
    Assignees: Centre National de la Recherche Scientifique-CNRS, Universite Nice Sophia Antipolis
    Inventors: Emmanuel Deval, Sylvie Diochot, Michel Lazdunski, Eric Lingueglia, Jacques Noel
  • ANALGESIC EFFECTS OF PEPTIDE TOXIN APETX2
    Publication number: 20110152197
    Abstract: The invention relates to the use of the peptide toxin APETx2 that blocks the ASIC3 cationic channels and that is derived from the Anthopleura elegantissima sea anemone, and to the use of the analogs and derivatives thereof as a drug, particularly as an analgesic pain associated with the activation of ASIC3 (Acid Sensing Ion Channel 3) channels, in particular pain occurring upon an inflammation and potentially upon any painful situation associated with tissue acidosis (ischemiae, fractures, hematoma, oedema, phlyctena, local infections, tissue lesions, ocular wounds, tumours, etc.
    Type: Application
    Filed: June 4, 2009
    Publication date: June 23, 2011
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS-, UNIVERSITE NICE SOPHIA ANTIPOLIS
    Inventors: Emmanuel Deval, Sylvie Diochot, Michel Lazdunski, Eric Lingueglia, Jacques Noel