Patents by Inventor Eric Mertz

Eric Mertz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8471027
    Abstract: The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein the variables are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. Disclosed are methods and formulations for inhibiting JNK and treating JNK-mediated disorders, and the like, with the compounds, and processes for making said compounds, and corresponding compositions, disclosed herein.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: June 25, 2013
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Adrian Wai-Hing Cheung, Kevin Richard Guertin, Nancy-Ellen Haynes, Eric Mertz, Lida Qi, Yimin Qian, Nathan Robert Scott
  • Publication number: 20130018043
    Abstract: The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein the variables are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. Disclosed are methods and formulations for inhibiting JNK and treating JNK-mediated disorders, and the like, with the compounds, and processes for making said compounds, and corresponding compositions, disclosed herein.
    Type: Application
    Filed: July 11, 2012
    Publication date: January 17, 2013
    Inventors: Joseph A. Bilotta, Adrian Wai-Hing Cheung, Fariborz Firooznia, Kevin Richard Guertin, Stuart Hayden, Nancy-Ellen Haynes, Christine M. Lukacs-Lesburg, Nicholas Marcopulos, Eric Mertz, Lida Qi, Yimin Qian, Sung-Sau So, Jenny Tan, Kshitij C. Thakkar
  • Patent number: 8346439
    Abstract: A system and method of activating a restraint system of a vehicle is described. The method includes generating a vehicle speed signal that represents a longitudinal speed of a vehicle, generating a lateral acceleration signal that represents a lateral acceleration of the vehicle, filtering the lateral acceleration signal to generate a filtered lateral acceleration signal, comparing the filtered lateral acceleration signal to a predetermined lateral acceleration enable threshold, estimating a lateral speed of the vehicle based on the vehicle speed signal when the filtered lateral acceleration exceeds the predetermined lateral acceleration enable threshold, and activating a restraint system of the vehicle based in part on the estimated lateral velocity.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: January 1, 2013
    Assignee: Continental Teves, Inc.
    Inventors: Robert Andres, Patrick Messi, Eric Mertz, Holger Faisst
  • Publication number: 20120258982
    Abstract: The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein the variables are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. Disclosed are methods and formulations for inhibiting JNK and treating JNK-mediated disorders, and the like, with the compounds, and processes for making said compounds, and corresponding compositions, disclosed herein.
    Type: Application
    Filed: April 3, 2012
    Publication date: October 11, 2012
    Inventors: Adrian Wai-Hing Cheung, Kevin Richard Guertin, Nancy-Ellen Haynes, Eric Mertz, Lida Qi, Yimin Qian, Nathan Robert Scott
  • Publication number: 20120209476
    Abstract: Disclosed is a method to determine a vehicle's lateral velocity during abnormal driving situations of a vehicle during controlled side-impact or rollover crash tests that involve the pulling of a vehicle sideways into an object. A high-resolution, low-range, lateral accelerometer is integrated to determine the lateral velocity. Furthermore, is a method to initiate the integration of the acceleration signal and a method to stop and reset the integration. The method recognizes special conditions associated with abnormal driving situations like controlled crash tests, and therefore will not be active during normal operating conditions. The method also includes a means to handle offset tolerances associated with accelerometers by finding the sensor's zero-g point while the vehicle is at rest.
    Type: Application
    Filed: July 16, 2010
    Publication date: August 16, 2012
    Inventors: Robert M. Andres, Holger Faisst, Eric Mertz, Helmut Steurer
  • Patent number: 8124629
    Abstract: The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
    Type: Grant
    Filed: November 9, 2009
    Date of Patent: February 28, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Fariborz Firooznia, Paul Gillespie, Tai-An Lin, Eric Mertz, Achyutharao Sidduri, Sung-Sau So, Jenny Tan, Kshitij Chhabilbhai Thakkar
  • Publication number: 20100137250
    Abstract: The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
    Type: Application
    Filed: November 9, 2009
    Publication date: June 3, 2010
    Inventors: Fariborz Firooznia, Paul Gillespie, Tai-An Lin, Eric Mertz, Achyutharao Sidduri, Sung-Sau So, Jenny Tan, Kshitij Chhabilbhai Thakkar
  • Publication number: 20100125058
    Abstract: The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein W, X, Y, and R1-R7 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
    Type: Application
    Filed: November 9, 2009
    Publication date: May 20, 2010
    Inventors: Li Chen, Fariborz Firooznia, Paul Gillespie, Yun He, Tai-An Lin, Eric Mertz, Sung-Sau So, Hong Ying Yun, Zhenshan Zhang
  • Publication number: 20070007066
    Abstract: A method of operating a load limiting restraint system including the steps of receiving an acceleration value and also receiving a signal indicative of an occupant size. The signal received of occupant size is combined with the acceleration value to predict a load on the occupant and the restraint system. If the predicted load exceeds a predicted load value then the load limiting device is actuated to gradually reduce and selectively release the seatbelt.
    Type: Application
    Filed: June 26, 2006
    Publication date: January 11, 2007
    Applicant: Siemens VDO Automotive Corporation
    Inventor: Eric Mertz
  • Publication number: 20050004729
    Abstract: A vehicle safety system (20) includes a controller (24) that verifies the plausibility of a roll angle indication obtained by processing a roll angular rate sensor (26) output. The controller (24) determines whether an acceleration value corresponding to the roll angle indication is within an expected range. In a disclosed example, the controller (24) utilizes a vertical acceleration value and a first expected range and a lateral acceleration value and a second expected range. When both of the acceleration values are outside of the respective expected range, the controller determines that the roll angle indication is invalid.
    Type: Application
    Filed: June 25, 2004
    Publication date: January 6, 2005
    Applicant: Siemens VDO Automotive Corporation
    Inventors: Jeffrey Gleacher, Ciprian Lucut, Robert Andres, Andreas Knueppel, Thomas Malbouef, Douglas McConnell, Eric Mertz, Scott Morell