Patents by Inventor Erkki Heinonen

Erkki Heinonen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100137789
    Abstract: A drug delivery presentation is disclosed herein. The drug delivery presentation includes a display for showing a concentration of at least two different types of drugs including a first drug and a second drug for a subject, and also for showing a coordinate system for a variable first drug concentration and a variable second drug concentration. The drug delivery presentation also includes an optimal therapy mixture area presented on a coordinate system comprising a first border section determining a minimum concentration mixture for the first drug and the second drug. The optimal therapy mixture area further comprising a second border section determining a maximum concentration mixture for the first drug and the second drug. An arrangement for a drug delivery presentation is also disclosed.
    Type: Application
    Filed: November 24, 2009
    Publication date: June 3, 2010
    Inventors: Erkki HEINONEN, Tom HAGGBLOM
  • Patent number: 7699789
    Abstract: A method for measuring lung collapse and for providing information regarding recruitment and successfulness of actions taken to recruit the lung is provided. Alveolar- and proximal pressures are determined at different lung pressures or volumes. Patient airway resistance is calculated combining these measurements with flow measurement. Plotting the resistance against the lung pressure or volume gives a within-breath distribution of the resistance. Increase of this resistance at end-expiration volume or pressure indicates lung collapse.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: April 20, 2010
    Assignee: The General Electric Company
    Inventors: Erkki Heinonen, Sören Söndergaard
  • Patent number: 7681574
    Abstract: The functional residual capacity (FRC) value of a subject's lungs determined for each breath is related a volume dilution factor kn and the final FRC value is determined at the point where the volume dilution factor kn reaches a predetermined volume dilution factor value. The determination of the final FRC value can be based on interpolation or extrapolation from a measured breath data series. The volume dilution factor may be normalized value. This is achieved by division of all volume dilution factors with the initially determined volume dilution factor. With normalization, the compartments in which gas concentration change is achieved slowly are referenced with the faster, more effective compartments, thus giving a ventilation profile of the lungs.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: March 23, 2010
    Assignee: General Electric Company
    Inventor: Erkki Heinonen
  • Publication number: 20090288659
    Abstract: An apparatus for administering an anesthetic agent for a subject breathing. The apparatus includes a liquid reservoir for an anesthetic agent and an anesthetic agent dosing unit in fluid connection with the liquid reservoir and which anesthetic agent dosing unit is connectable to an airway tube for delivering breathing gases to a subject, said dosing unit including a first member to produce anesthetic agent droplets having a diameter less than 100 ?m.
    Type: Application
    Filed: May 13, 2009
    Publication date: November 26, 2009
    Inventors: Heikki Haveri, Erkki Heinonen
  • Publication number: 20070144520
    Abstract: The functional residual capacity (FRC) value of a subject's lungs determined for each breath is related a volume dilution factor kn and the final FRC value is determined at the point where the volume dilution factor kn reaches a predetermined volume dilution factor value. The determination of the final FRC value can be based on interpolation or extrapolation from a measured breath data series. The volume dilution factor may be normalized value. This is achieved by division of all volume dilution factors with the initially determined volume dilution factor. With normalization, the compartments in which gas concentration change is achieved slowly are referenced with the faster, more effective compartments, thus giving a ventilation profile of the lungs.
    Type: Application
    Filed: December 22, 2005
    Publication date: June 28, 2007
    Inventor: Erkki Heinonen
  • Publication number: 20070125378
    Abstract: A method and apparatus for providing an average signal characteristic profile relating first and second physiological properties, the average signal characteristic profile being derived from signals obtained from different cycles of a cyclically recurring physiological phenomenon. A signal produced from a first cycle of the physiological phenomenon is sampled at a series of data points of a first physiological property to obtain second physiological property values of the first cycle signal at the data points. The signal produced from a second cycle of the physiological phenomenon is sampled at a series of data points corresponding to those of the first series of data points to obtain second physiological property values of the second cycle signal at the data points.
    Type: Application
    Filed: December 2, 2005
    Publication date: June 7, 2007
    Inventor: Erkki Heinonen
  • Publication number: 20070129646
    Abstract: A method and apparatus for determining the presence or absence of a pulmonary embolism (PE) in a patient. The breathing gas CO2 partial pressure (PCO2) during the expiration of breathing gases by the patient, the end tidal (EtCO2), CO2 partial pressure, and the CO2 partial pressure (PaCO2) of the blood are measured. The volume (V) of breathing gases expired during the expiration of breathing gases by the patient is also measured and a relationship between changes in breathing gas CO2 partial pressure (PCO2) and changes in breathing gas volume (V) in an alveolar expiration phase of patient expiration is determined. The difference between the blood CO2 partial pressure (PaCO2) and the end expiration CO2 partial pressure is divided by the relationship between PCO2 and V produce a quantity which is compared to a threshold value. If the quantity is below the threshold value, the absence of a pulmonary embolism is indicated.
    Type: Application
    Filed: December 2, 2005
    Publication date: June 7, 2007
    Inventors: Erkki Heinonen, Rene Coffeng, Franck Verschuren
  • Publication number: 20070125377
    Abstract: A ventilation system for intensified breathing that includes both a manual ventilation system and automatic ventilation system. The gas mixture from a gas supply system is supplied to a switching valve that is operable between a manual position and an automatic position. When the switching valve is in the manual position, the inhalation gas from the supply system is guided to a manual ventilation bag. When the ventilation bag is squeezed during manual inhalation, the gas flow from the manual bag is directed to the inhalation limb of the patient circuit. When the manual ventilation bag is released, the pressure within the ventilation bag falls below the exhalation pressure, thereby indicating the beginning of the exhalation phase and the re-inflation of the manual ventilation.
    Type: Application
    Filed: November 30, 2006
    Publication date: June 7, 2007
    Inventors: Erkki Heinonen, Leif Bromster
  • Publication number: 20070062528
    Abstract: A method for measuring lung collapse and for providing information regarding recruitment and successfulness of actions taken to recruit the lung is provided. Alveolar- and proximal pressures are determined at different lung pressures or volumes. Patient airway resistance is calculated combining these measurements with flow measurement. Plotting the resistance against the lung pressure or volume gives a within-breath distribution of the resistance. Increase of this resistance at end-expiration volume or pressure indicates lung collapse.
    Type: Application
    Filed: September 21, 2005
    Publication date: March 22, 2007
    Inventors: Erkki Heinonen, Soren Sondergaard
  • Patent number: 7070569
    Abstract: A method for non-invasively determining functional cardiac output (FCO) and/or venous blood CO2 partial pressure (PvCO2). The amount of CO2 (VCO2N) released from the blood and end capillary blood CO2 content (CcCO2N) are determined from measurements from exhaled breathing gases. The CO2 content of the breathing gases inhaled by the subject is increased and values for VCO2R and CcCO2R are obtained. A regression analysis is performed using the obtained VCO2N, VO2R, CcCO2N, and CcCO2R values. The regression line is extrapolated to obtain a value for CcCO2 when (VCO2) is zero so that CvCO2 becomes known. The CvCO2 thus determined can be inserted in a non-differential form in the Fick equation, along with VCO2 and CcCO2 values from normal breathing, to determine FCO. To determine PvCO2, CvCO2 is altered in accordance with the amount of oxygen in the venous blood, to correctly indicate PvCO2.
    Type: Grant
    Filed: March 4, 2002
    Date of Patent: July 4, 2006
    Assignee: Instrumentarium Corp.
    Inventors: Erkki Heinonen, Jan Ekstrom
  • Patent number: 6983750
    Abstract: A method of determining ventilation inhomogeneity in the lungs is provided. During the first step of the method, a lung volume series is calculated from a series of measured lung inert gas concentrations and lung inert gas volumetric change measured data series. As a second step, the series of lung volumes is completed with a series of value representing the total gas exchange efficiency in the lungs. A global inert gas dilution ratio may be used for this purpose. The gas exchange efficiency values are such that less ventilation is represented by lower numbers. As the third step, the gas exchange efficiency series is plotted as an ordinate and lung volume series as an abscissa to form a graph. From this graph both the lung volume and homogeneity of ventilation become directly apparent.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: January 10, 2006
    Assignee: Instrumentarium Corp.
    Inventor: Erkki Heinonen
  • Patent number: 6951216
    Abstract: Apparatus and method for providing breathing gases to a subject employs an exchanger taking up a quantity of a given component, such as CO2, from expiratory breathing gases passing through the exchanger and thereafter releasing the given component in inspiratory breathing gases subsequently passing through the exchanger. The exchanger may be selectively inserted in a flow path for the breathing gases for this purpose. Or, the breathing gases may be selectively passed through and bypassed around the exchanger. The apparatus and method may be used for non-invasive determination of the functional cardiac output of a patient using the differential form of the Fick equation.
    Type: Grant
    Filed: December 19, 2002
    Date of Patent: October 4, 2005
    Assignee: Instrumentarium Corp.
    Inventor: Erkki Heinonen
  • Patent number: 6892726
    Abstract: The invention relates to an arrangement in connection with equipment used in patient care, the arrangement comprising a controllable device (2a, 2b), a measuring device (5a, 5b) adapted to measure a measuring signal dependent on the controllable parameter, a measuring point of the measuring signal, a transmission link (21, 22) between the measuring point of the measuring signal and the measuring device, which transmission link requires a separate connection, whereby the measuring device (5a, 5b) is adapted to convert the measuring signal into measuring value which correlates with the operation of the controllable device, and the arrangement further comprising a user interface (20) and a control unit (7a, 7b) adapted to control the controllable device on the basis of the measuring value and the set values.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: May 17, 2005
    Assignee: Instrumentarium Corp.
    Inventors: Erkki Heinonen, Pekka Meriläinen, Antti Särelä, Mario Loncar
  • Patent number: 6868851
    Abstract: A liquid reservoir for a nebulizer is comprised of a pair of membranes formed of resilient material and sealed about their edges to form a closed chamber between them for containing a liquid to be nebulized. When the chamber is filled with liquid and thereby expanded, the resilient membranes are distended to apply pressure to the liquid in the chamber. A discharge valve controls the discharge of liquid from the reservoir to the nebulizer under the pressure applied by the membranes. The reservoir is mounted on the nebulizer so that one of the membranes abuts a surface of the nebulizer that concavely deforms the membrane to increase the pressure applied to the liquid in the chamber to reduce or eliminate any residual volume of liquid in the chamber at the end of the discharging operation.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: March 22, 2005
    Assignee: Instrumentarium Corp.
    Inventor: Erkki Heinonen
  • Publication number: 20050045180
    Abstract: A method of determining ventilation inhomogeneity in the lungs is provided. During the first step of the method, a lung volume series is calculated from a series of measured lung inert gas concentrations and lung inert gas volumetric change measured data series. As a second step, the series of lung volumes is completed with a series of value representing the total gas exchange efficiency in the lungs. A global inert gas dilution ratio may be used for this purpose. The gas exchange efficiency values are such that less ventilation is represented by lower numbers. As the third step, the gas exchange efficiency series is plotted as an ordinate and lung volume series as an abscissa to form a graph. From this graph both the lung volume and homogeneity of ventilation become directly apparent.
    Type: Application
    Filed: August 26, 2003
    Publication date: March 3, 2005
    Inventor: Erkki Heinonen
  • Publication number: 20040118402
    Abstract: Apparatus and method for providing breathing gases to a subject employs an exchanger taking up a quantity of a given component, such as CO2, from expiratory breathing gases passing through the exchanger and thereafter releasing the given component in inspiratory breathing gases subsequently passing through the exchanger. The exchanger may be selectively inserted in a flow path for the breathing gases for this purpose. Or, the breathing gases may be selectively passed through and bypassed around the exchanger. The apparatus and method may be used for non-invasive determination of the functional cardiac output of a patient using the differential form of the Fick equation.
    Type: Application
    Filed: December 19, 2002
    Publication date: June 24, 2004
    Inventor: Erkki Heinonen
  • Patent number: 6694969
    Abstract: A method for improving oxygenation in subjects having essentially healthy lungs, as evidenced by the absence of a diagnosis of lung disease or injury, but having reduced alveolar gas exchange area. This reduction may be caused by such acute circumstances as an unnatural body position, or may be, for example, chronic as caused by obesity. The method employs the administration of nitric oxide (NO) into the breathing gases of such subjects. NO provided to alveoli collapsing during expiration is small compared to those remaining open, thereby to provide net reduction in the shunt and thus an oxygenation improvement. This result may be gained either by precise control of the inspired NO concentration or by pulsed administration of the NO.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: February 24, 2004
    Assignee: Instrumentarium Corp.
    Inventors: Erkki Heinonen, Pekka Meriläinen, Görel Nyman, Marieann Högman
  • Patent number: 6681643
    Abstract: A method and apparatus for determining a state of zero gas flow in a conduit. A first gas flow signal has one polarity when gas flow is in one direction in the conduit and the opposite polarity when gas flow is in the opposite direction. A second gas flow signal has the same polarity for either direction of gas flow in the conduit. The derivatives of the first and second signals are taken at successive points in time to determine when the signs of the derivatives are present in a first predetermined combination of signs. A second point in time when the signs of the derivatives exhibit a second predetermined combination of signs different from the first combination is also determined. The combinations of signs are used to identify a state of zero gas flow in the conduit.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: January 27, 2004
    Assignee: Instrumentarium Corp.
    Inventor: Erkki Heinonen
  • Publication number: 20030140919
    Abstract: A liquid reservoir for a nebulizer is comprised of a pair of membranes formed of resilient material and sealed about their edges to form a closed chamber between them for containing a liquid to be nebulized. When the chamber is filled with liquid and thereby expanded, the resilient membranes are distended to apply pressure to the liquid in the chamber. A discharge valve controls the discharge of liquid from the reservoir to the nebulizer under the pressure applied by the membranes. The reservoir is mounted on the nebulizer so that one of the membranes abuts a surface of the nebulizer that concavely deforms the membrane to increase the pressure applied to the liquid in the chamber to reduce or eliminate any residual volume of liquid in the chamber at the end of the discharging operation.
    Type: Application
    Filed: January 31, 2002
    Publication date: July 31, 2003
    Inventor: Erkki Heinonen
  • Patent number: 6530370
    Abstract: A nebulizer apparatus to atomize liquid solutions or suspensions. The nebulizer is typically used in conjunction with a breathing circuit to deliver atomized medicine to a patient. A housing with an opening covered by a thin mesh plate is supplied with the liquid to be nebulized on an “on-demand” basis. The mesh plate or liquid is vibrated at ultrasonic frequencies to atomize the liquid as it passes through the plate into breathing gases flowing through the breathing tube.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: March 11, 2003
    Assignee: Instrumentation Corp.
    Inventor: Erkki Heinonen