Patents by Inventor Ernesto Oppici

Ernesto Oppici has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4668821
    Abstract: The invention discloses a method for extracting phenylalanine from the broths obtained by enzymatic processes; this method consists in flocculating and filtering the broth, concentrating the filtrate followed by filtering off the resulting cinnamic acid, decolorating and concentrating the filtrate to obtain phenylalanine crystals at a very pure degree.
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: May 26, 1987
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Onorino G. Rosa, Carlo Varesio, Ernesto Oppici
  • Patent number: 4656304
    Abstract: A process for the preparation of the N-L-.alpha.-aspartyl-L-phenylalanine 1-methyl ester (aspartame) which is characterized by adding phosphoric acid and a lower alkyl alcohol to the reaction mixture containing N-formyl .alpha.-L-aspartyl- and .beta.-L-aspartyl-L-phenyl-alanine methyl ester and only one of the resultant deformylated isomers, i.e. aspartame phosphate precipitates.The .alpha.-isomer phosphate is collected by filtration and converted to free aspartame by treatment with a base.
    Type: Grant
    Filed: May 25, 1984
    Date of Patent: April 7, 1987
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Ernesto Oppici, Franco Dallatomasina, Pietro Giardino
  • Patent number: 4568740
    Abstract: Disclosed is a process for purifying Tylosin by selective adsorption of the fermentation broth previously brought to 7.5-10.0 pH on polymeric resins and by subsequent deadsorption of the purified product with a aqueous-alcoholic or aqueous-acetonic solution and further purification of the eluate by filtration through macroreticular weak anion resins.
    Type: Grant
    Filed: March 28, 1984
    Date of Patent: February 4, 1986
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Ernesto Oppici, Onorino G. Rosa, Carlo Varesio, Giovanni Lazzari, Danillo Fabris
  • Patent number: 4549987
    Abstract: A process for deformylation and separation of N-formyl-L- .alpha.-aspartyl-L-phenylalanine methyl ester from a mixture containing both .alpha. and .beta. isomers thereof, which comprises admixing with said isomeric mixture hydrogen peroxide and an organic acid.
    Type: Grant
    Filed: August 6, 1984
    Date of Patent: October 29, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Franco Dallatomasina, Roberto Ortica, Pietro Giardino, Ernesto Oppici
  • Patent number: 4021426
    Abstract: A process for preparing 6-APA and 7-ACA and derivatives therefore is disclosed wherein a penicillin or cephalosporin substrate is reacted with a molar excess of an oxalyl halide of the formula halCOCOhal whereby the COOM group of the substrate, wherein M represents hydrogen, metal or ammonium cations, is transformed into the group COOCOCOhal.
    Type: Grant
    Filed: July 17, 1975
    Date of Patent: May 3, 1977
    Assignee: Gruppo Lepetit S.p.A.
    Inventors: Ernesto Oppici, Anacleto Gianantonio
  • Patent number: 3983109
    Abstract: Cephalosporin C is recovered from its fermentation broth by in situ formation of N-(p-nitrobenzoyl)cephalosporin C which is extracted therefrom and converted to 7-amino-cephalosporanic acid.
    Type: Grant
    Filed: December 30, 1974
    Date of Patent: September 28, 1976
    Assignee: Gruppo Lepetit S.p.A.
    Inventors: Ernesto Oppici, Anacleto Gianantonio
  • Patent number: 3953513
    Abstract: Process for preparing an .alpha.-aminoalcohol of formula ##EQU1## wherein R represents hydrogen or alkyl of from 1 to 5 carbon atoms, which comprises contacting a compound of formula ##EQU2## wherein R has the same meaning as above, with an alcohol of formula R'-OH wherein R' represents benzyl or the group ##EQU3## in which R" and R"' are independently selected from hydrogen and alkyl of from 1 to 4 carbon atoms in an organic solvent, in the presence of a basic catalyst, at from about 140.degree. to about 170.degree.C., treating the obtained product of formula ##EQU4## wherein R and R' have the above meanings, with at least an equimolecular amount of a p-toluene-sulfonyl halide, at from about -5.degree. to about 20.degree.C. in the presence of a tertiary organic nitrogen-containing base and reacting in a closed system the resulting compound of formula ##EQU5## wherein R and R' are as above defined, with an excess of gaseous ammonia, in the presence of an inert organic solvent, at from about 95.degree.
    Type: Grant
    Filed: November 8, 1974
    Date of Patent: April 27, 1976
    Assignee: Gruppo Lepetit S.p.A.
    Inventor: Ernesto Oppici