Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a biasing member, and a priming indicator. The syringe body defines a syringe cavity, a syringe port, and an indicator window, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger comprises a first plunger shaft extending from the first plunger, the first plunger disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The biasing member couples to the first plunger shaft, wherein the biasing member urges the first plunger from an unprimed position to a primed position toward the syringe port. The priming indicator presents the first indicator portion through the indicator window in the unprimed position and presents the second indicator portion through the indicator window in the primed position.

Abstract: Check valve assemblies for fluid flow sets and devices are provided. The check valve assembly includes a housing having an inlet body and an outlet body. The inlet body includes a fluid inlet, a first seal bead having a first height, a second seal bead having a second height and a central channel. The outlet body includes a fluid outlet and a stem having a centering post, the centering post received by the central channel of the inlet body. A seal has an inner ring with a first thickness and an outer ring with a second thickness less than the first thickness. The inner ring is engaged with the first seal bead and the outer ring is engaged with the second seal bead in a fully sealed position of the check valve assembly. Fluid flow sets and methods for manufacturing check valve assemblies are also provided.

Abstract: An physiological measurement device provides a device body having a base, legs extending from the base and an optical housing disposed at ends of the legs opposite the base. An optical assembly is disposed in the housing. The device body is flexed so as to position the housing over a tissue site. The device body is unflexed so as to attach the housing to the tissue site and position the optical assembly to illuminate the tissue site. The optical assembly is configured to transmit optical radiation into tissue site tissue and receive the optical radiation after attenuation by pulsatile blood flow within the tissue.

Abstract: Check valve assemblies for fluid flow sets and devices are provided. The check valve assembly includes a housing having an inlet body and an outlet body. The inlet body includes a fluid inlet, a first seal bead having a first height, a second seal bead having a second height and a central channel. The outlet body includes a fluid outlet and a stem having a centering post, the centering post received by the central channel of the inlet body. A seal has an inner ring with a first thickness and an outer ring with a second thickness less than the first thickness. The inner ring is engaged with the first seal bead and the outer ring is engaged with the second seal bead in a fully sealed position of the check valve assembly. Fluid flow sets and methods for manufacturing check valve assemblies are also provided.

Abstract: An physiological measurement device provides a device body having a base, legs extending from the base and an optical housing disposed at ends of the legs opposite the base. An optical assembly is disposed in the housing. The device body is flexed so as to position the housing over a tissue site. The device body is unflexed so as to attach the housing to the tissue site and position the optical assembly to illuminate the tissue site. The optical assembly is configured to transmit optical radiation into tissue site tissue and receive the optical radiation after attenuation by pulsatile blood flow within the tissue.

Abstract: Check valve are disclosed having a primary seal and a secondary seal, where the primary and secondary seals resist movement of a fluid through the check valve, and the secondary seal can provide a backup seal in an instance where the check valve does not function as intended. The primary and secondary seals can be formed by first and second sealing ridges, respectively, and a valve body can be positioned within the check valve, between a valve support, the first sealing ridge, and a second sealing ridge. The valve body is configured to move relative to the first and second sealing ridges, and can have a position wherein a portion of the valve body is engaged against any of the first and second sealing ridges.

Abstract: Valve bodies are described herein. A valve body is disclosed to control fluid flow through a drip chamber defining a chamber volume and comprises a chamber body coupling, a valve inlet, a valve outlet, and a needle valve assembly. The chamber body coupling receives the drip chamber. The valve inlet or the valve outlet is configured to be in fluid communication with the chamber volume. The needle valve assembly comprises a fixed needle valve surface; and a movable needle valve surface, wherein the movable needle valve surface is axially movable relative to the fixed needle valve surface to control a flow rate between the valve inlet and the valve outlet.

Abstract: Syringe control assemblies are described herein. A syringe control assembly includes an assembly body, a first syringe, a second syringe, and a pump assembly. The first and second syringes are releasably coupled to a syringe mounting rack of the assembly body. The pump assembly includes a first pump unit and a second pump unit. Each pump unit is in fluid communication with each respective syringe. In a priming configuration, the first pump unit is configured to draw fluid flow from the first syringe cavity and the second pump unit is configured to pump fluid flow into the second syringe cavity.

Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.

Abstract: A method of manufacturing a check valve may include forming an upper housing as cylindrical body with (i) an internal surface including an upstream internal surface and a downstream internal surface having a projection and (ii) an external surface, forming a T-shaped filter member and mounting the T-shaped filter member in the internal surface of the upper housing. The method may further include forming a lower housing with a support portion at a central portion thereof, mounting a flexible valve member on the support portion, and coupling the upper housing with T-shaped filter member mounted therein onto the lower housing with flexible valve member mounted therein such that the T-shaped filter member is disposed upstream of the flexible valve member.

Abstract: A check valve may include an upper housing defining an inlet, a lower housing defining an outlet, and a cavity interposed between and defined by the upper and lower housings for fluidly connecting the inlet and the outlet. The check valve may further include a flexible valve member mounted in the cavity to selectively permit fluid flow in a first direction, and prevent fluid backflow in a second direction opposite to the first direction. A filter member may be mounted in the upper housing, upstream of the flexible valve member. The filter member may have an elongated portion configured to maximize surface area thereof exposed to the fluid flow, and restrict passage of undesirable matter in fluid flowing through the check valve.

Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a biasing member, and a priming indicator. The syringe body defines a syringe cavity, a syringe port, and an indicator window, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger comprises a first plunger shaft extending from the first plunger, the first plunger disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The biasing member couples to the first plunger shaft, wherein the biasing member urges the first plunger from an unprimed position to a primed position toward the syringe port. The priming indicator presents the first indicator portion through the indicator window in the unprimed position and presents the second indicator portion through the indicator window in the primed position.

Abstract: Valves and medication delivery systems including valves are described herein. A valve includes a valve body and a valve element. The valve body defines a first flow path, a second flow path, and a catheter flow path. The valve element is disposed within the valve body, wherein the valve element is configured to permit fluid communication between the first flow path and the second flow path in a priming position, and is configured to permit fluid communication between the first flow path and the catheter flow path in a dispensing position.

Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a biasing member, and a retention member. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger comprises a first plunger shaft extending from the first plunger, the first plunger disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The biasing member is coupled to the first plunger shaft, wherein the biasing member urges the first plunger to advance toward the syringe port. The retention mechanism prevents the biasing member from advancing the first plunger in an engaged position and permits the biasing member to advance the first plunger in a released position.

Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a second plunger, and an inner tube. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger is disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The second plunger is disposed within the syringe cavity, the first plunger and the second plunger cooperatively defining a second chamber in the syringe cavity. The inner tube comprises an inner tube lumen, wherein the inner tube and the first plunger shaft lumen define an annulus therebetween, the annulus in fluid communication with the first plunger channel and the annulus permits fluid communication between the syringe port and the first plunger channel.

Abstract: A check valve includes an upper housing having an inlet of the check valve, a lower housing axially coupled to the upper housing and having an outlet of the check valve, a valve portion cooperatively formed by the upper and lower housings, a passageway extending between the inlet and outlet, a first filter included in the upper housing to limit passage of undesirable matter in fluid flowing through the check valve, a second filter included in the lower housing to limit passage of undesirable matter in fluid flowing through the check valve, each of the first filter and the second filter including a plurality of vertical structures disposed in the valve portion and extending axially and radially in the valve portion, and a valve member positioned in the valve portion to selectively permit fluid to flow through the check valve.

Abstract: A check valve includes an upper housing defining an inlet of the check valve, a lower housing defining an outlet of the check valve, and a cavity interposed between and defined by the upper and lower housings for fluidly connecting the inlet and the outlet. The check valve further includes a valve member mounted in the cavity to selectively permit fluid flow in a first direction, and prevent fluid backflow in a second direction opposite to the first direction. The valve member includes a valve body and a valve stem portion extending axially through a central axis of the valve body. The valve member may further include a plurality of feet disposed about and extending longitudinally from an outer circumferential perimeter of the valve body.

Abstract: A check valve includes an upper housing having an inlet of the check valve, a lower housing axially coupled to the upper housing and having an outlet of the check valve, a valve portion cooperatively formed by the upper and lower housings, a passageway extending between the inlet and outlet, a first filter included in the upper housing to limit passage of undesirable matter in fluid flowing through the check valve, a second filter included in the lower housing to limit passage of undesirable matter in fluid flowing through the check valve, each of the first filter and the second filter including a plurality of vertical structures disposed in the valve portion and extending axially and radially in the valve portion, and a valve member positioned in the valve portion to selectively permit fluid to flow through the check valve.

Abstract: A check valve may include an upper housing defining an inlet, a lower housing defining an outlet, and a cavity interposed between and defined by the upper and lower housings for fluidly connecting the inlet and the outlet. The check valve may further include a flexible valve member mounted in the cavity to selectively permit fluid flow in a first direction, and prevent fluid backflow in a second direction opposite to the first direction. A filter member may be mounted in the upper housing, upstream of the flexible valve member. The filter member may have an elongated portion configured to maximize surface area thereof exposed to the fluid flow, and restrict passage of undesirable matter in fluid flowing through the check valve.

Abstract: An exemplary syringe adapter for coupling with a syringe may include a housing. A needle-free connector may be disposed in the housing. A communication member may be in slidable engagement with the housing. The communication member may be slidable, with respect to the housing, between an unactuated state and an actuated state of the syringe adapter. A cannula may extend from the communication. In the unactuated state, the cannula may be retracted within the needle-free connector. In the actuated state, the cannula may protrude through and axially beyond the needle-free connector.