Abstract: The present disclosure relates to STING (Stimulator of Interferon Genes) agonist compounds, methods of making the compounds and their methods of use.

Abstract: Table top sanitizer dispenser bottle bases are disclosed herein. An exemplary table top sanitizer dispenser bottle base includes a movable upper housing, the upper moveable housing has a floor with an aperture located therein and a peripheral wall. The top sanitizer dispenser bottle includes a lower stationary housing. The upper movable housing is connected to the lower stationary housing and is configured to move linearly upward and downward with respect to lower stationary. One or more biasing members bias the upper movable housing upward. A switch is included and the upper movable housing has an engagement member or surface for actuating the switch upon downward movement of the upper movable housing. At least one of a visual indicator and an audible indicator are also included. Control circuitry is provided for activating the one or more of a visual indicator and audible indicator when the engagement member actuates the switch.

Abstract: A vented pump includes a pump housing with a fluid retention cavity, a fluid inlet, and at least one vent opening therethrough. A pump dome is secured to the pump housing to form a dome cavity. Movement of the pump dome allows material from the fluid retention cavity to enter the dome cavity through the fluid inlet, and selectively allows ambient air to enter the fluid retention cavity through the at least one vent opening.

Abstract: Wipe dispensers are provided wherein particular wipe-gripping and wipe-ripping structures are provided to overcome problems encountered with the prior art. Particularly, gripping and ripping structures are provided to prevent the removal of more than one wipe at a time from a dispenser and to prevent a following wipe from falling back into the interior of a container when separated from a lead wipe being removed from the container. In particular embodiments, structures are provided to avoid pinching an individual's finger when feeding a wipe up through the gripping and ripping structures. In yet other particular embodiments, a boss is provided to prevent wipes from bunching up during the dispensing thereof.

Abstract: A vented pump includes a pump housing with a fluid retention cavity, a fluid inlet, and at least one vent opening therethrough. A pump dome is secured to the pump housing to form a dome cavity. Movement of the pump dome allows material from the fluid retention cavity to enter the dome cavity through the fluid inlet, and selectively allows ambient air to enter the fluid retention cavity through the at least one vent opening.

Abstract: Exemplary embodiments of collapsible containers are disclosed herein. Some exemplary embodiments include a container having a plurality of sides. The plurality of sides forms a substantially geometric shape, such as a rectangular shape. A plurality of predetermined fold lines extend substantially across each of the sides and the predetermined fold lines form a plurality of geometric shapes. A plurality of predetermined fold lines for inner folds on a first side are aligned with a plurality of predetermined fold lines for outer folds on a second side.

Abstract: A wipes dispenser includes a container having an interior holding a plurality of wipes. A grip orifice provides communication between the interior and the exterior of the container, and the grip orifice serves to prevent wipes from falling back into the interior. The dispenser also includes a rip fence, and a lead end of a lead wipe of the plurality of wet wipes within the container extends through the grip orifice and then through the rip fence such that pulling on the lead end to pull the lead wipe against the rip fence causes the remainder of the lead wipe to be removed from the container and become disassociated with the remaining wipes of the plurality of wipes. As the lead end is pulled against the rip fence, the following wipe of the plurality of wipes is pulled through the grip orifice to provide its lead end outside of the interior of the container, and the grip orifice prevents this lead end of the following wipe from falling back into the interior of the container.

Abstract: One embodiment for dispensers for dispensing wet wipes includes a container, a plurality of wet wipes contained within the container and a dispensing nozzle made of a resilient material secured to the container. The dispensing nozzle includes an outlet opening in the nozzle. A fluid retaining member is located at a point below the opening. Another embodiment includes a container for holding a plurality of wipes. A dispensing nozzle includes a resilient member having an outlet opening is secured to the container. A fluid retaining member is located below the outlet. In one embodiment, the fluid retaining member has a surface that is sloped. Embodiments of dispensing nozzles for wet wipes are also disclosed wherein the dispensing nozzle includes a resilient dome shaped member having an opening located therein. In addition, the dispensing nozzle includes an annular fluid retaining ring. The annular fluid retaining ring may have a sloped surface.

Abstract: A wipes dispenser includes a container having an interior holding a plurality of wipes. A grip orifice provides communication between the interior and the exterior of the container, and the grip orifice serves to prevent wipes from falling back into the interior. The dispenser also includes a rip fence, and a lead end of a lead wipe of the plurality of wet wipes within the container extends through the grip orifice and then through the rip fence such that pulling on the lead end to pull the lead wipe against the rip fence causes the remainder of the lead wipe to be removed from the container and become disassociated with the remaining wipes of the plurality of wipes. As the lead end is pulled against the rip fence, the following wipe of the plurality of wipes is pulled through the grip orifice to provide its lead end outside of the interior of the container, and the grip orifice prevents this lead end of the following wipe from falling back into the interior of the container.

Abstract: Exemplary methods and apparatuses for heating preforms are disclosed herein. An exemplary apparatus for heating a preform includes a gripping portion for gripping a preform.

Abstract: Liquid dispenser systems, pumps for use in liquid dispenser systems, and disposable/replaceable liquid container units for use in liquid dispenser systems are disclosed. A refill unit for refilling a liquid dispenser system comprises a container for holding a supply of liquid and a pump connected to the container. The pump comprises a fitment portion configured for attachment to a liquid container, and a pump portion which comprises an upper valve member and a lower valve member disposed along a common longitudinal axis, such that the fitment portion and the pump portion are formed as one integral piece.

Abstract: Exemplary dispensers having non-collapsible containers and venting pumps are disclosed herein. Some exemplary dispensers include a rigid container for holding a liquid and a pump secured to the container. The pump has a liquid pump portion and an air pump portion. The liquid pump portion has a one-way liquid inlet valve, a liquid pump chamber and a liquid outlet valve. Expansion of the liquid chamber causes liquid to flow from the container past the liquid inlet valve into the pump chamber. Compression of the liquid chamber causes liquid to flow from the pump chamber past the liquid outlet valve. In addition, the air pump portion includes an air pump chamber, a piston, a one-way air inlet valve and a filter. Compression of the air pump chamber causes air to flow through the filter and past the one-way air inlet valve into the container.

Abstract: Exemplary metered dose dispensers are disclosed herein. One exemplary embodiment includes a container and a one-dose dispenser secured to the container. The one-dose dispenser includes a dosing chamber; a shuttle member movable within the dosing chamber; an outlet valve located at an end of the dosing chamber and an outlet located downstream of the outlet valve. A liquid inlet is also included for allowing liquid to flow into the dosing chamber to an area between the shuttle member and the outlet valve. Pressurizing liquid in the container moves the shuttle member from a first position to a second position and dispenses the liquid in the dosing chamber; and when the shuttle member is in the second position, the shuttle member seals off the outlet valve.

Abstract: Exemplary embodiments of collapsible containers are disclosed herein. Some exemplary embodiments include a container having a plurality of sides. The plurality of sides forms a substantially geometric shape, such as a rectangular shape. A plurality of predetermined fold lines extend substantially across each of the sides and the predetermined fold lines form a plurality of geometric shapes. A plurality of predetermined fold lines for inner folds on a first side are aligned with a plurality of predetermined fold lines for outer folds on a second side.

Abstract: One embodiment for dispensers for dispensing wet wipes includes a container, a plurality of wet wipes contained within the container and a dispensing nozzle made of a resilient material secured to the container. The dispensing nozzle includes an outlet opening in the nozzle. A fluid retaining member is located at a point below the opening. Another embodiment includes a container for holding a plurality of wipes. A dispensing nozzle includes a resilient member having an outlet opening is secured to the container. A fluid retaining member is located below the outlet. In one embodiment, the fluid retaining member has a surface that is sloped. Embodiments of dispensing nozzles for wet wipes are also disclosed wherein the dispensing nozzle includes a resilient dome shaped member having an opening located therein. In addition, the dispensing nozzle includes an annular fluid retaining ring. The annular fluid retaining ring may have a sloped surface.

Abstract: A pump head for a displacement pump used in a bottle dispenser and configured to minimize misdirection of solution dispensed through an orifice thereof. The pump head is an integrally molded one piece structure, having an elliptical outlet orifice that lies in a substantially horizontal plane, and having a major axis substantially twice that of the minor axis. The configuration and the positioning of the orifice minimizes clogging or coagulation of certain solutions, obscures such coagulation from view, and minimizes the misdirection of any dispensing through the nozzle orifice that would otherwise result from clogging or coagulation. The pump head is particularly adapted for use with displacement pumps employed in bottle dispensers and the like.

Abstract: Embodiments of foam pumps and refill units for foam dispensers are disclosed herein. An exemplary embodiment of a foam pump includes a housing, a mixing chamber located within the housing, an inlet into the mixing chamber and an outlet valve located downstream of the mixing chamber. In addition, a sealing member movable in a first direction and a second direction is included and provided in the housing, the sealing member being movable in the first direction by pressurized air. The pressurized air causes the sealing member to move in the first direction and open a pathway for pressurized air to travel through the inlet and enter the mixing chamber. Upon a decrease in the air pressure, the sealing member moves in the second direction and closes off the inlet from pressurized air.

Abstract: Liquid dispenser systems, pumps for use in liquid dispenser systems, and disposable/replaceable liquid container units for use in liquid dispenser systems are disclosed. A refill unit for refilling a liquid dispenser system comprises a container for holding a supply of liquid and a pump connected to the container. The pump comprises a fitment portion configured for attachment to a liquid container, and a pump portion which comprises an upper valve member and a lower valve member disposed along a common longitudinal axis, such that the fitment portion and the pump portion are formed as one integral piece.

Abstract: A pump head for a displacement pump used in a bottle dispenser and configured to minimize misdirection of solution dispensed through an orifice thereof. The pump head is an integrally molded one piece structure, having an elliptical outlet orifice that lies in a substantially horizontal plane, and having a major axis substantially twice that of the minor axis. The configuration and the positioning of the orifice minimizes clogging or coagulation of certain solutions, obscures such coagulation from view, and minimizes the misdirection of any dispensing through the nozzle orifice that would otherwise result from clogging or coagulation. The pump head is particularly adapted for use with displacement pumps employed in bottle dispensers and the like.

Abstract: Embodiments of foam pumps and refill units for foam dispensers are disclosed herein. An exemplary embodiment of a foam pump includes a housing, a mixing chamber located within the housing, an inlet into the mixing chamber and an outlet valve located downstream of the mixing chamber. In addition, a sealing member movable in a first direction and a second direction is included and provided in the housing, the sealing member being movable in the first direction by pressurized air. The pressurized air causes the sealing member to move in the first direction and open a pathway for pressurized air to travel through the inlet and enter the mixing chamber. Upon a decrease in the air pressure, the sealing member moves in the second direction and closes off the inlet from pressurized air.