Abstract: A novel hexapeptide having the following structure:Phe-Ala-Gly-Phe-Gly-Arg.The hexapeptide according to the present invention has a hepatoprotective effect.

Abstract: A novel hexapeptide having the following structure:Tyr-Ala-Gly-Phe-Leu-Arg.The hexapeptide according to the present invention possesses an antipancreonecrotic activity.

Abstract: Urokinase derivatives comprise urokinase covalently bonded with fibrinogen or urokinase covalently bonded with fibrinogen through an aliphatic diamine and correspond to the general formula: ##STR1## wherein P is fibrinogen, E is urokinase, R is absent or stands for ##STR2## wherein n is 1-12, with a molecular mass of from 360,000 to 440,000 D, a content of protein of 10 to 30% by mass, an esterase catalytic activity of 30-60%.These derivatives have an increased affinity to fibrin and feature a prolonged fibrinolytic effect.

Abstract: A pharmaceutical preparation for the treatment of diabetes mellitus comprising the following components, in percent by weight:______________________________________ crystalline insulin with a conventional 1 to 25.0 activity of 1 mg = 20 units additives inhibiting deactivation of insulin, 0.02 to 10.0 viz. 5-(para-[N--(3-methoxypyridazinyl-6)- sulphamido]-phenylazo)-salicylic acid, calcium gluconate or a mixture thereof preservatives 0.1 to 15.0 additives adjusting solubility of 0.01 to 10.0 insulin water-soluble polymeric base the balance.

Abstract: A method of preparing a polysaccharide derivative of fibrinolysin which comprises reacting fibrinolysin with dextran dialdehyde having a molecular mass of from 20,000 to 110,000 at a pH of from 8.0 to 9.5 and at a temperature within the range of from 5.degree. to 30.degree. C. with the formation of a covalent bond; the resulting fibrinolysin derivative is reduced with sodium borohydride and isolated.

Abstract: A heat-resistant water soluble derivative of urokinase is prepared which comprises urokinase covalently bonded to a copolymer of acrylamide and acrylic acid having a molecular weight of 10,000 to 200,000 and a content of acrylic acid of 1% to 2%. The derivative contains 15% to 35% urokinase and has an esterase and amidolytic activity of from 10% to 80%.

Abstract: A method for producing a visible image of an object is disclosed in which a fermental plate is illuminated with ultrasonic waves and a latent image of the object is therefore produced therein which is developed using a solution of chromogenic substrates, comprising, for example, hydrogen peroxide and a water-soluble aromatic amine. An apparatus to practice the disclosed method comprises an ultrasonic generator to generate ultrasonic waves illuminating the object, a fermental plate to receive and convert the ultrasonic waves passed through the object to a visible image, and a tray filled with a developer to develop the latent image of the object in the fermental plate.

Abstract: The extracorporeal circulation apparatus in accordance with the invention comprises a plurality of pneumatic diaphragm pumps incorporated in parallel relationship in a single fluid-flow system of extracorporeal blood perfusion.The electronic control system of the arrangement which processes the EKG signals is provided with a control signal distributor for sequential pump actuation such that the priming time of each pump is prolonged, frothing and haemolysis of the blood is prevented, and the stroke volume of the apparatus is maintained at a predetermined level.