Patents by Inventor Fabiola Cecchi

Fabiola Cecchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for use of vascular endothelial growth factor antagonists
    Patent number: 9550818
    Abstract: The present invention provides variant VEGF polypeptides which have been altered in their C-terminal heparin binding region to lower their heparin binding affinity. These variants have been found to act as receptor antagonists for VEGF receptors and antagonize angiogenesis. These variants are useful to treat diseases characterized by pathological angiogenesis.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: January 24, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Donald P. Bottaro, Fabiola Cecchi
  • VASCULAR ENDOTHELIAL GROWTH FACTOR ANTAGONISTS AND METHODS FOR THEIR USE
    Publication number: 20150126446
    Abstract: The present invention provides variant VEGF polypeptides which have been altered in their C-terminal heparin binding region to lower their heparin binding affinity. These variants have been found to act as receptor antagonists for VEGF receptors and antagonize angiogenesis. These variants are useful to treat diseases characterized by pathological angiogenesis.
    Type: Application
    Filed: April 26, 2013
    Publication date: May 7, 2015
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health & Human Services
    Inventors: Donald P. Bottaro, Fabiola Cecchi