Patents by Inventor Fangyi Zhu

Fangyi Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9416124
    Abstract: In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl -1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: August 16, 2016
    Assignees: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MMV MEDICINES FOR MALARIA VENTURE, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Rodney Kiplin Guy, Fangyi Zhu, Wendyam Armand Guiguemde, David Floyd, Spencer Knapp, Philip Stein, Steve Castro
  • Publication number: 20140235593
    Abstract: In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl-1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: August 24, 2012
    Publication date: August 21, 2014
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, MMV MEDICINES FOR MALARIA VENTURE
    Inventors: Rodney Kiplin Guy, Fangyi Zhu, Wendyam Armand Guiguemde, David Floyd, Spencer Knapp, Philip Stein, Steve Castro
  • Patent number: 8470785
    Abstract: Compositions and methods for treating ocular cancer are provided. The composition is a subconjunctival formulation of nutlin-3 and its analogs. The composition provides for methods of treating ocular cancer, including retinoblastoma. The formulation has high penetration into ocular tissue with low toxicity.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: June 25, 2013
    Assignees: St. Jude Children's Research Hospital, Leiden University Medical Center, VIB VZW and Universiteit Gent
    Inventors: Michael A. Dyer, Jean-Christophe Marine, Aart Gerrit Jochemsen, R. Kip Guy, Fangyi Zhu
  • Patent number: 8236929
    Abstract: Methods and systems for obtaining zein and/or xanthophylls in highly pure form. Zein is first extracted from corn using aqueous ethanol. Suspended corn solids are separated, and the resulting extract is purified in a single size-exclusion chromatography step to separate impurities and produce substantially purified zein. The chromatography step may simultaneously produce substantially purified xanthophylls.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: August 7, 2012
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Munir Cheryan, Aniket V. Kale, Fangyi Zhu, Philip L. Shane
  • Publication number: 20090215990
    Abstract: Methods and systems for obtaining zein and/or xanthophylls in highly pure form. Zein is first extracted from corn using aqueous ethanol. Suspended corn solids are separated, and the resulting extract is purified in a single size-exclusion chromatography step to separate impurities and produce substantially purified zein. The chromatography step may simultaneously produce substantially purified xanthophylls.
    Type: Application
    Filed: May 8, 2007
    Publication date: August 27, 2009
    Inventors: Munir Cheryan, Aniket V. Kale, Fangyi Zhu, Philip L. Shane