Patents by Inventor Fariba Nemati

Fariba Nemati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of predicting a response to an anti-tumor treatment
    Patent number: 10508310
    Abstract: The invention provides an in vitro method for determining the likelihood for a patient affected with a tumor to respond to a treatment with a pro-apoptotic peptide able to disrupt interaction between caspase 9 and PP2A, which method comprises determining expression level of at least each of VIM, MK167, TCF7L2, NEK2, BIRC5, MCL1, and PLK1 genes, in a biological sample of said patient.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: December 17, 2019
    Assignees: SORBONNE UNIVERSITE, INSTITUT CURIE
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin
  • Peptide inhibitors of TEAD/YAP-TAZ interaction
    Patent number: 10077294
    Abstract: The invention relates to an isolated peptide inhibitor of the interaction between the TEAD and YAP or TAZ proteins and a derived chimeric peptide linked to a cell-penetrating peptide. These peptides which have a cytotoxic activity are useful, in particular for the treatment of hyperproliferative disorders such as cancer.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: September 18, 2018
    Assignees: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), INSTITUT CURIE
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin
  • Cell-penetrating peptides
    Patent number: 9644001
    Abstract: A vector that includes a cell-penetrating peptide linked to a therapeutic agent. The therapeutic agent can be a cytotoxic agent, an anti-viral agent, an anti-bacterial agent, or an anti-parasitic agent.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: May 9, 2017
    Assignees: Universite Pierre Et Marie Curie (Paris 6), Institut Curie
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
  • PRO-APOPTOTIC RAS AND RAF PEPTIDES
    Publication number: 20170015718
    Abstract: The invention relates to pro-apoptotic peptides, useful in cancer treatment, and to chimeric peptides comprising a cell penetrating peptide linked to a pro-apoptotic peptide, wherein the pro-apoptotic peptide binds Ras or Raf proteins.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 19, 2017
    Inventors: ANGELITA REBOLLO GARCIA, FARIBA NEMATI, DIDIER DECAUDIN
  • A METHOD OF PREDICTING A RESPONSE TO AN ANTI-TUMOR TREATMENT
    Publication number: 20160312293
    Abstract: The invention provides an in vitro method for determining the likelihood for a patient affected with a tumor to respond to a treatment with a pro-apoptotic peptide able to disrupt interaction between caspase 9 and PP2A, which method comprises determining expression level of at least each of VIM, MK167, TCF7L2, NEK2, BIRC5, MCL1, and PLK1 genes, in a biological sample of said patient.
    Type: Application
    Filed: December 9, 2014
    Publication date: October 27, 2016
    Inventors: ANGELITA REBOLLO GARCIA, FARIBA NEMATI, DIDIER DECAUDIN
  • PEPTIDE INHIBITORS OF TEAD/YAP-TAZ INTERACTION
    Publication number: 20160264636
    Abstract: The invention relates to an isolated peptide inhibitor of the interaction between the TEAD and YAP or TAZ proteins and a derived chimeric peptide linked to a cell-penetrating peptide. These peptides which have a cytotoxic activity are useful, in particular for the treatment of hyperproliferative disorders such as cancer.
    Type: Application
    Filed: November 4, 2014
    Publication date: September 15, 2016
    Inventors: Angelita REBOLLO GARCIA, Fariba NEMATI, Didier DECAUDIN
  • CELL-PENETRATING PEPTIDES
    Publication number: 20160257713
    Abstract: The invention relates to a cell-penetrating peptide, optionally linked to a pro-apoptotic peptide, useful as pro-apoptotic agents, for inhibition of in vitro cell proliferation and for treatment of tumors.
    Type: Application
    Filed: May 26, 2016
    Publication date: September 8, 2016
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
  • Anti-tumor adjuvant therapy
    Patent number: 9364514
    Abstract: A chimeric peptide construct having a cell penetrating peptide linked to a pro-apoptotic peptide. The construct can be used for treating a tumor in combination with an anti-tumor agent. Also disclosed is a method for treating a tumor with the chimeric peptide construct and a chemotherapeutic agent.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: June 14, 2016
    Assignees: Institute Curie, Universite Pierre et Marie Curie (Paris 6)
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin
  • Cell-penetrating peptides
    Patent number: 9353155
    Abstract: A cell-penetrating peptide is described. Also described is a pro-apoptotic agent including the cell-penetrating peptide and a pro-apoptotic peptide linked thereto. The pro-apoptotic agent is useful for inhibition of in vitro cell proliferation and for treatment of tumors.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: May 31, 2016
    Assignees: Universite Pierre et Marie Curie (Paris 6), Institute Curie
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
  • ANTI-TUMOR ADJUVANT THERAPY
    Publication number: 20150030699
    Abstract: The invention relates to a chimeric peptide construct comprising a cell penetrating peptide linked to a pro-apoptotic peptide, for use in treating a tumor in combination with an anti-tumor agent, preferably a chemotherapeutic agent.
    Type: Application
    Filed: December 27, 2012
    Publication date: January 29, 2015
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin
  • CELL-PENETRATING PEPTIDES
    Publication number: 20140364376
    Abstract: The invention relates to a cell-penetrating peptide, optionally linked to a pro-apoptotic peptide, useful as pro-apoptotic agents, for inhibition of in vitro cell proliferation and for treatment of tumors.
    Type: Application
    Filed: December 27, 2012
    Publication date: December 11, 2014
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
  • CHIMERIC PEPTIDES INCLUDING A PENETRATING PEPTIDE AND A BINDING DOMAIN OF PP2A CATALYTIC SUBUNIT TO CASPASE-9
    Publication number: 20130303439
    Abstract: The invention related to chimeric peptides including a penetrating peptide and a binding domain of PP2A catalytic subunit to caspase-9 which have pro-apoptotic activity. These chimeric peptides may be used for the treatment of hyperproliferative disorders.
    Type: Application
    Filed: September 30, 2011
    Publication date: November 14, 2013
    Applicants: Institut National de la Sante et de la Recherche Medicale (INSERM), INSTITUT CURIE
    Inventors: Angelita Rebollo Garcia, Didier Decaudin, Fariba Nemati
  • Medicines for treating tumoral pathologies containing the ro5-4864 compound and an apoptosis-inducing agent
    Publication number: 20030166598
    Abstract: The invention concerns the use of Ro5-4864, and compounds derived therefrom, for preparing medicines for treating tumoral pathologies. The invention also concerns said compounds combined with an apoptosis-inducing agent, as combination products for simultaneous, separate or prolonged use, in cancer therapy.
    Type: Application
    Filed: April 8, 2003
    Publication date: September 4, 2003
    Inventors: Didier Decaudin, Guido Kroemer, Marie-France Poupon, Fariba Nemati, Arnaud Beurdeley-Thomas