Patents by Inventor FLORIAN DAMIEN MEDINA

FLORIAN DAMIEN MEDINA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES AND INTERMEDIATES FOR PREPARING A BTK INHIBITOR
    Publication number: 20230107573
    Abstract: Disclosed is a process for the preparation of certain intermediates, e.g. the following compound: which intermediate and processes are useful in the preparation of a BTK inhibitor, such as ibrutinib.
    Type: Application
    Filed: April 13, 2022
    Publication date: April 6, 2023
    Inventors: Cyril Ben Haim, Thomas Joost Martti Michiels, Florian Damien Medina, Simon Albert Wagschal, Dominique Paul M. Depré
  • IMPROVED SYNTHETIC METHODS OF MAKING (2H-1, 2, 3-TRIAZOL-2-YL) PHENYL COMPOUNDS AS OREXIN RECEPTOR MODULATORS
    Publication number: 20220289754
    Abstract: Processes for preparing (((3aR,6aS)-5-(4,6-dimethylpyrimidin-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)methanone are described, which are useful for commercial manufacturing. Said compound is an orexin receptor modulator and may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia and depression.
    Type: Application
    Filed: August 6, 2020
    Publication date: September 15, 2022
    Applicant: JANSSEN PHARMACEUTICA NV
    Inventors: DOMINIQUE PAUL M DEPRE, KIRAN MATCHA, FLORIAN DAMIEN MEDINA, PIETER WESTERDUIN, CHENG YI CHEN