Patents by Inventor Fook Chiong Cheong

Fook Chiong Cheong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200319086
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Application
    Filed: April 24, 2020
    Publication date: October 8, 2020
    Applicant: NEW YORK UNIVERSITY
    Inventors: David G. GRIER, Fook Chiong CHEONG, Ke XIAO
  • Patent number: 10634604
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: April 28, 2020
    Assignee: NEW YORK UNIVERSITY
    Inventors: David G. Grier, Fook Chiong Cheong, Ke Xiao
  • Publication number: 20190234853
    Abstract: Holographic microscopy analysis system and methods for determining morphology of a particle in a sample. A bright-field reconstruction image is generated from a recorded hologram from a holographic microscopy system. Morphology of particles imaged by the system may be determined. Hu moments are calculated, either from the hologram or from the bright-field reconstruction, or both, to provide an indication of morphology.
    Type: Application
    Filed: August 24, 2017
    Publication date: August 1, 2019
    Inventors: David B. RUFFNER, Laura PHILIPS, Fook Chiong CHEONG
  • Patent number: 10234451
    Abstract: The disclosure relates to a method and device for detecting and quantifying biological molecules such as cell surface or intracellular ligands/receptors in a dynamic system with high sensitivity and specificity; the method of using such platform optionally in combination with an optical detection system and kits comprising the optical platform.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: March 19, 2019
    Assignee: National University of Singapore
    Inventors: Ramesh Ramji, Fook Chiong Cheong, Chwee Teck Lim
  • Patent number: 9989451
    Abstract: A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by providing a laser source to output a collimated beam, scattering the collimated beam off a particle and interacting with an unscattered beam to generate the interference pattern for analyzation to determine the refractive index of the particle and a medium disposed in the porosity of the particle to measure porosity and the medium.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: June 5, 2018
    Assignee: NEW YORK UNIVERSITY
    Inventors: Fook Chiong Cheong, Ke Xiao, David Pine, David G. Grier
  • Publication number: 20180011001
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Application
    Filed: July 31, 2017
    Publication date: January 11, 2018
    Inventors: David G. GRIER, Fook Chiong CHEONG, Ke XIAO
  • Patent number: 9719911
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: August 1, 2017
    Assignee: NEW YORK UNIVERSITY
    Inventors: David G. Grier, Fook Chiong Cheong, Ke Xiao
  • Publication number: 20170191920
    Abstract: A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by providing a laser source to output a collimated beam, scattering the collimated beam off a particle and interacting with an unscattered beam to generate the interference pattern for analyzation to determine the refractive index of the particle and a medium disposed in the porosity of the particle to measure porosity and the medium.
    Type: Application
    Filed: December 12, 2016
    Publication date: July 6, 2017
    Applicant: National Science Foundation
    Inventors: Fook Chiong Cheong, Ke Xiao, David Pine, David G. Grier
  • Patent number: 9519129
    Abstract: A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by providing a laser source to output a collimated beam, scattering the collimated beam off a particle and interacting with an unscattered beam to generate the interference pattern for analyzation to determine the refractive index of the particle and a medium disposed in the porosity of the particle to measure porosity and the medium.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: December 13, 2016
    Assignee: New York University
    Inventors: Fook Chiong Cheong, Ke Xiao, David Pine, David G. Grier
  • Publication number: 20160216195
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Application
    Filed: April 4, 2016
    Publication date: July 28, 2016
    Applicant: New York University
    Inventors: David G. GRIER, Fook Chiong CHEONG, Ke XIAO
  • Patent number: 9316578
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: April 19, 2016
    Assignee: New York University
    Inventors: David G. Grier, Fook Chiong Cheong, Ke Xiao
  • Publication number: 20160069874
    Abstract: The disclosure relates to a method and device for detecting and quantifying biological molecules such as cell surface or intracellular ligands/receptors in a dynamic system with high sensitivity and specificity; the method of using such platform optionally in combination with an optical detection system and kits comprising the optical platform.
    Type: Application
    Filed: September 4, 2015
    Publication date: March 10, 2016
    Applicant: National University of Singapore
    Inventors: Ramesh Ramji, Fook Chiong Cheong, Chwee Teck Lim
  • Publication number: 20130278743
    Abstract: A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by providing a laser source to output a collimated beam, scattering the collimated beam off a particle and interacting with an unscattered beam to generate the interference pattern for analyzation to determine the refractive index of the particle and a medium disposed in the porosity of the particle to measure porosity and the medium.
    Type: Application
    Filed: November 4, 2011
    Publication date: October 24, 2013
    Applicant: New York University
    Inventors: Fook Chiong Cheong, Ke Xiao, David Pine, David G. Grier
  • Patent number: 8331019
    Abstract: A method and system for performing three-dimensional holographic microscopy of an optically trapped one dimensional structure. The method and system use an inverted optical microscope, a laser source which generates a trapping laser beam wherein the laser beam is focused by an objective lens into a plurality of optical traps. The method and system also use a collimated laser at an imaging wavelength to illuminate the structure created by the optical traps. Imaging light scattered by the optically tapped structure forms normalized intensity holograms that are imaged by a video camera and analyzed by optical formalisms to determine light field to reconstruct 3-D images for analysis and evaluation.
    Type: Grant
    Filed: April 14, 2010
    Date of Patent: December 11, 2012
    Assignee: New York University
    Inventors: Fook Chiong Cheong, David G. Grier, Sang-Hyuk Lee
  • Publication number: 20120135535
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Application
    Filed: January 14, 2010
    Publication date: May 31, 2012
    Inventors: David G. Grier, Fook Chiong Cheong, Ke Xiao
  • Publication number: 20100253762
    Abstract: A method and system for performing three-dimensional holographic microscopy of an optically trapped one dimensional structure. The method and system use an inverted optical microscope, a laser source which generates a trapping laser beam wherein the laser beam is focused by an objective lens into a plurality of optical traps. The method and system also use a collimated laser at an imaging wavelength to illuminate the structure created by the optical traps. Imaging light scattered by the optically tapped structure forms normalized intensity holograms that are imaged by a video camera and analyzed by optical formalisms to determine light field to reconstruct 3-D images for analysis and evaluation.
    Type: Application
    Filed: April 14, 2010
    Publication date: October 7, 2010
    Inventors: Fook Chiong CHEONG, David G. Grier, Sang-Hyuk Lee